scholarly journals Ethylene vinyl alcohol copolymer to treat an intracranial arteriovenous malformation in a dog

2021 ◽  
Author(s):  
William T. N. Culp ◽  
Ann Gratzek ◽  
Merrianne Burtch ◽  
Brian C. Dahlin ◽  
Paul R. Dong ◽  
...  
Keyword(s):  
Arteriovenous Malformation ◽  
Vinyl Alcohol ◽  
Intracranial Arteriovenous Malformation ◽  
Ethylene Vinyl Alcohol ◽  
Ethylene Vinyl Alcohol Copolymer

Surgical handling characteristics of an ethylene vinyl alcohol copolymer compared with N-butyl cyanoacrylate used for embolization of vessels in an arteriovenous malformation resection model in swine

2003 ◽  
Vol 98 (2) ◽  
pp. 366-370 ◽  
Author(s):  
Eric D. Akin ◽  
Eddie Perkins ◽  
Ian B. Ross
Keyword(s):  
Blood Loss ◽  
Arteriovenous Malformation ◽  
Vinyl Alcohol ◽  
Treated Group ◽  
Content Type ◽  
Ethylene Vinyl Alcohol ◽  
Ethylene Vinyl Alcohol Copolymer ◽  
Rete Mirabile ◽  
Handling Characteristics ◽  
Fine Print

Object. There have been significant improvements in neurovascular technology and implants over the past decade. One such material, N-butyl cyanoacrylate (NBCA), is now commercially available for cerebral arteriovenous malformation (AVM) embolization in the US. An ethylene vinyl alcohol copolymer preparation, Onyx, which is currently being evaluated, is approved for use outside North America. Although reports indicate that Onyx may be superior to NBCA from an endovascular perspective, little information exists about its surgical handling characteristics. The purpose of this study was to compare the surgical handling characteristics of Onyx-treated vessels with those of NBCA-embolized vessels in an AVM resection model. Methods. Fourteen pigs (two groups of seven) were anesthetized. A femoral artery was cannulated, followed by selective catheterization of the ascending pharyngeal arteries. Nidal rete mirabile (RM) embolizations were performed using either 6% Onyx or 20% NBCA. After angiographically confirmed obliteration of flow in the right RM, microsurgical resection of this structure was performed. Surgical handling characteristics of the embolized RM were rated on a scale of 1 to 5 and blood loss was recorded. Different surgeons performed the embolizations and resections. The surgeon who performed resections was blinded to the embolization agent used, and the data analysis was also performed in a blinded fashion. The surgical handling scores were superior (p < 0.05) in the Onyx-treated group. Although there was also less blood loss in this group, the difference was not significant. Subjectively, the surgeon who performed the resections believed that Onyx was softer and handled better than NBCA. Conclusions. Onyx, which may offer endovascular advantages, also seems to provide benefits for the surgeon.

Pancreatic Arteriovenous Malformation Involving the Duodenum Embolized with Ethylene-Vinyl Alcohol Copolymer (Onyx)

2011 ◽  
Vol 35 (4) ◽  
pp. 958-962 ◽  
Author(s):  
Rosario Francesco Grasso ◽  
Roberto Luigi Cazzato ◽  
Giacomo Luppi ◽  
Eliodoro Faiella ◽  
Riccardo Del Vescovo ◽  
...  
Keyword(s):  
Arteriovenous Malformation ◽  
Vinyl Alcohol ◽  
Ethylene Vinyl Alcohol ◽  
Pancreatic Arteriovenous Malformation ◽  
Ethylene Vinyl Alcohol Copolymer
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