scholarly journals Untargeted metabolomic profiling of serum from dogs with chronic hepatic disease

2019 ◽  
Vol 33 (3) ◽  
pp. 1344-1352 ◽  
Author(s):  
Yuri A. Lawrence ◽  
Micah A. Bishop ◽  
Julia B. Honneffer ◽  
Audrey K. Cook ◽  
Aline Rodrigues‐Hoffmann ◽  
...  
Keyword(s):  
Hepatic Disease ◽  
Metabolomic Profiling ◽  
Chronic Hepatic Disease

scholarly journals Untargeted metabolomic profiling of urine from healthy dogs and dogs with chronic hepatic disease

PLoS ONE ◽  
2019 ◽  
Vol 14 (5) ◽  
pp. e0217797 ◽  
Author(s):  
Yuri A. Lawrence ◽  
Blake C. Guard ◽  
Jörg M. Steiner ◽  
Jan S. Suchodolski ◽  
Jonathan A. Lidbury
Keyword(s):  
Hepatic Disease ◽  
Metabolomic Profiling ◽  
Chronic Hepatic Disease ◽  
Healthy Dogs

Sonography of subcutaneous tissue cannot determine causes of lower limb edema

VASA ◽  
2015 ◽  
Vol 44 (2) ◽  
pp. 122-128 ◽  
Author(s):  
Mandy Becker ◽  
Tom Schilling ◽  
Olga von Beckerath ◽  
Knut Kröger
Keyword(s):  
Clinical Diagnosis ◽  
Lower Limb ◽  
Subcutaneous Tissue ◽  
Hepatic Disease ◽  
Clinical Use ◽  
Single Image ◽  
Heart Insufficiency ◽  
Chronic Hepatic Disease ◽  
Limb Edema ◽  
Venous Disorders

Background: To clarify the clinical use of sonography for differentiation of edema we tried to answer the question whether a group of doctors can differentiate lymphedema from cardiac, hepatic or venous edema just by analysing sonographic images of the edema. Patients and methods: 38 (70 ± 12 years, 22 (58 %) females) patients with lower limb edema were recruited according the clinical diagnosis: 10 (26 %) lymphedema, 16 (42 %) heart insufficiency, 6 (16 %) venous disorders, 6 (16 %) chronic hepatic disease. Edema was depicted sonographically at the most affected leg in a standardised way at distal and proximal calf. 38 sets of images were anonymised and send to 5 experienced doctors. They were asked whether they can see criteria for lymphedema: 1. anechoic gaps, 2. horizontal gaps and 3. echoic rims. Results: Accepting an edema as lymphedema if only one doctor sees at least one of the three criteria for lymphatic edema on each single image all edema would be classified as lymphatic. Accepting lymphedema only if all doctors see at least one of the three criteria on the distal image of the same patient 80 % of the patients supposed to have lymphedema are classified as such, but also the majority of cardiac, venous and hepatic edema. Accepting lymphedema only if all doctors see all three criteria on the distal image of the same patients no edema would be classified as lymphatic. In addition we separated patients by Stemmers’ sign in those with positive and negative sign. The interpretation of the images was not different between both groups. Conclusions: Our analysis shows that it is not possible to differentiate lymphedema from other lower limb edema sonographically.

scholarly journals Target Therapies for NASH/NAFLD: From the Molecular Aspect to the Pharmacological and Surgical Alternatives

2021 ◽  
Vol 11 (6) ◽  
pp. 499
Author(s):  
Michele Finotti ◽  
Maurizio Romano ◽  
Pasquale Auricchio ◽  
Michele Scopelliti ◽  
Marco Brizzolari ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Fatty Liver Disease ◽  
Hepatic Disease ◽  
Lifestyle Modifications ◽  
Alcoholic Fatty Liver ◽  
Target Therapies ◽  
Chronic Hepatic Disease ◽  
The Impact ◽  
Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease represents an increasing cause of chronic hepatic disease in recent years. This condition usually arises in patients with multiple comorbidities, the so-called metabolic syndrome. The therapeutic options are multiple, ranging from lifestyle modifications, pharmacological options, to liver transplantation in selected cases. The choice of the most beneficial one and their interactions can be challenging. It is mandatory to stratify the patients according to the severity of their disease to tailor the available treatments. In our contribution, we review the most recent pharmacological target therapies, the role of bariatric surgery, and the impact of liver transplantation on the NAFLD outcome.

scholarly journals Arrhythmia Risk in Patients with ChronicHepatic Disease

2018 ◽  
Vol 69 (11) ◽  
pp. 3337-3340 ◽  
Author(s):  
Veronica Calborean ◽  
Victor Gheorman ◽  
Sorin Nicolae Dinescu ◽  
Diana Stanca ◽  
Oana Galceava ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Liver Cirrhosis ◽  
Risk Factor ◽  
Causes Of Death ◽  
Hepatic Disease ◽  
Cardiac Symptoms ◽  
Ventricular Extrasystoles ◽  
The World ◽  
Chronic Hepatic Disease ◽  
Somatic Status

Cardiac affectation is one of the leading causes of death in the world. Rhythmic disorders such as ventricular extrasystoles, atrial extrasysoles, atrial fibrillation, atrial flutter represent a major risk factor with a gloomy progression and prognosis. Our goal was to analyze the existing arrhythmia risk in patients with chronic hepatic disease. Being known the alteration of the somatic status of the patient with liver cirrhosis or other chronic liver disease in the presence of comorbid cardiac symptoms, we consider vital to prevent arrhythmia risk in hepatic pathology.

scholarly journals Pharmacological pain management in patients with chronic hepatic disease

2019 ◽  
Vol 10 (10.2) ◽  
pp. 119-123
Author(s):  
László Irsay ◽  
Alexandra Checiches ◽  
Dănuț Perja ◽  
Ileana Monica Borda ◽  
Gabriela Dogaru ◽  
...  
Keyword(s):  
Renal Function ◽  
Pain Management ◽  
Impaired Renal Function ◽  
Hepatic Dysfunction ◽  
Pain Medication ◽  
Hepatic Disease ◽  
Frequent Monitoring ◽  
Chronic Hepatic Disease ◽  
Treatment Administration ◽  
Health Organization

Abstract The liver has a central role in the pharmacokinetics (absorption, distribution, elimination, etc.) of drugs. With hepatic insufficiency, the metabolism of drugs decreases, which accumulates metabolically or toxic active products. Some medicines can aggravate a pre-existing liver disease. Medicines used in this group of patients (especially diuretics and centrally acting preparations) can often cause impaired renal function or hepatic encephalopathy. The general principles of assessment, pain management and analgesia should be prescribed taking into account the Word Health Organization (WHO) recommendations for these patients, with careful and frequent monitoring of patient progress during treatment administration. Key words: hepatotoxicity, hepatic dysfunction, cirrhosis, pain medication,

scholarly journals Examining the Frequency of Insulin Resistance in Children with Chronic Hepatic Disease

2019 ◽  
Vol 6 (2) ◽  
pp. 1-4
Author(s):  
Fatemeh Sadat Mirrashidi ◽  
Homa Ilkhanipoor ◽  
Seyed Mohsen Dehghani ◽  
Hossein Moravej
Keyword(s):  
Insulin Resistance ◽  
Hepatic Disease ◽  
Chronic Hepatic Disease

Fatty Liver Following Aureomycin and Terramycin Therapy in Chronic Hepatic Disease

1951 ◽  
Vol 18 (4) ◽  
pp. 598-605 ◽  
Author(s):  
Victor M. Sborov ◽  
Donald A. Sutherland
Keyword(s):  
Fatty Liver ◽  
Hepatic Disease ◽  
Chronic Hepatic Disease

Roentgen Examination of the Inferior Vena Cava in Chronic Hepatic Disease

1961 ◽  
Vol Original Series, Volume 55 (2) ◽  
pp. 97-102
Author(s):  
O. Petersen ◽  
N. Tygstrup ◽  
K. Winkler
Keyword(s):  
Inferior Vena Cava ◽  
Inferior Vena ◽  
Vena Cava ◽  
Hepatic Disease ◽  
Roentgen Examination ◽  
Chronic Hepatic Disease
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