scholarly journals Current management strategies and long-term clinical outcomes of upper extremity venous thrombosis

2016 ◽  
Vol 14 (5) ◽  
pp. 973-981 ◽  
Author(s):  
S. M. Bleker ◽  
N. van Es ◽  
A. Kleinjan ◽  
H. R. Büller ◽  
P. W. Kamphuisen ◽  
...  
Blood ◽  
2004 ◽  
Vol 104 (11) ◽  
pp. 4082-4082
Author(s):  
Lee Lin ◽  
Stanley Walker

Abstract Context Upper extremity deep venous thrombosis (DVT) represents 8–10% of total DVT of the limb. Long term central venous catheters represent a major cause of upper extremity DVT, especially in cancer patients. This study looks specifically at the risk posed by peripherally inserted central catheters (PICC). Purpose of the Study: To assess the risk of DVT and sepsis due to PICC lines in cancer patients as compared to non-cancer patients. Furthermore, to assess the risk of PICC line related DVT and sepsis among different cancer types. Design, Setting, and Patients: Retrospective chart review of all 190 patients (representing n=244 procedures) who had undergone a PICC line procedure in Union Memorial Hospital (Baltimore, MD) from August 2003 to December 2003. Based on their medical records, it was determined whether or not the patient had experienced PICC line related sepsis or thrombosis. Cancer as a potential risk factor was included in the information collected. 33 of 190 patients were cancer patients. Average patient age 56.7 years. Results: Preliminary results show that from August 1, 2003 to December 5, 2003, among the non-cancer patients 6 (3.8%) patients with DVT and 6 (3.8%) patients with sepsis were identified. Among the cancer patients, 3 (9.1%) patients with DVT and 3 (9.1%) patients with sepsis were identified. Though cancer patients made up only 17.4% of the patient population, they represented 33.3% of the cases of DVT and sepsis. Conclusion: Cancer patients are at a greater risk of thromboses and sepsis due to PICC lines as compared to non-cancer patients. Cancer patients, therefore, represent a unique population of PICC line patients who may require a different protocol of prophylaxis and complication prevention. While different types of cancers may pose different levels of risk (Sorensen et al), this could not be determined with confidence with the preliminary findings due to the small population evaluated so far. Non-cancer patients Cancer patients DVT 6 3.8% Sepsis 6 3.8% DVT 3 9.1% Sepsis 3 9.1%


Neurosurgery ◽  
2012 ◽  
Vol 72 (3) ◽  
pp. 407-414 ◽  
Author(s):  
Jin Wook Kim ◽  
Dong Gyu Kim ◽  
In Kyeong Kim ◽  
Yong Hwy Kim ◽  
Seung Hong Choi ◽  
...  

Abstract BACKGROUND: A thorough investigation of the long-term outcomes of central neurocytoma (CN) after different treatments is required to establish optimal management strategies. OBJECTIVE We retrospectively reviewed the long-term clinical outcomes of patients with CN according to various treatments and suggest treatment strategies based on 30 years of experience in a single institution. METHODS: Fifty-eight consecutive patients with CN were treated at our institution between 1982 and 2008. Patient demographics, overall survival, local control rates according to multimodal treatments, and functional outcomes were evaluated. The mean clinical and radiological follow-up periods were 119 months (range, 18-304 months) and 98 months (range, 13-245 months), respectively. RESULTS: The initial treatment modality was classified into 4 subgroups: operation only (34 patients), operation followed by radiation therapy (7 patients) or radiosurgery (7 patients), and radiosurgery alone (10 patients). The actuarial overall survival was 91% at 5 years and 88% at 10 years. The actuarial overall survival and local tumor control rate did not differ significantly according to the various treatments and the initial extent of the surgical resection. However, functional outcomes, such as the postoperative seizure outcome at the last follow-up, differed according to the surgical approach. CONCLUSION: The long-term clinical outcomes of CN after multimodal treatment seem to be excellent. Our study suggests that treatment strategies for CN should focus on the patient's quality of life, as well as on tumor control, because of the benign nature of CN.


2020 ◽  
Vol 11 ◽  
pp. 298
Author(s):  
Saleh Salah Safi ◽  
Khaled Murshed ◽  
Arshad Ali ◽  
Surjith Vattoth ◽  
Abdulrazzaq Haider ◽  
...  

Background: Rosai-Dorfman disease (RDD) is an idiopathic nonneoplastic lymphadenopathy disorder which is characterized by lymph node enlargement, but it may also presents primarily involving a variety of extranodal sites, including central nerves system and craniospinal axis. This study reports five cases of craniospinal RDD, with review of epidemiology, clinical presentation, imaging, and histopathological features with current management strategies. Case Description: Five cases of RDD are diagnosed at Hamad General Hospital, Qatar, during 2013–2018. Two cases had dural-based cranial lesions with overlying cranial involvement while three cases were having extradural thoracic spine lesions. All cases underwent surgical intervention and confirmed by histopathology. Conclusion: Craniospinal RDD is a rare clinical presentation and poses significant diagnostic challenges preoperatively due to its similarity with other neoplastic or inflammatory diseases. Surgical option to remove compressive neural pathology provides a good clinical outcome with no recurrence in long-term follow-up.


2020 ◽  
Vol 12 (20) ◽  
pp. 8482 ◽  
Author(s):  
Linas Balčiauskas ◽  
Yukichika Kawata ◽  
Laima Balčiauskienė

Moose (Alces alces) management strategies in Lithuania, East Europe, were analyzed. The study was intended to show the (un)sustainability of the current management approach in relation to changes in hunting rules, hunting organization and development of the responsible administrative bodies. Moose population and bag dynamics were analyzed using I index in connected scatterplots and compound annual growth rates (CAGR). In 1962–2020, the CAGR of the moose population was 3.84%, resulting in a population size increase of nearly 10 times. The seesaw principle in moose management was confirmed, showing three periods of population decrease (1973–1977, 1989–1995, 2000–2005), and two periods of hunting bag decrease (1976–1978 and 1990–1993). All decline phases were related to legal and administrative issues in the country. Since 2006, population growth has not been controlled. Lithuania has no long-term strategy of the moose population management at any administrative level. The current management approach is not sustainable, as it has not ensured long-term stability of the moose population. The current continuous growth of population, followed by only a moderate increase in the hunting bag, is related to the possibility for owners to adopt long-term planning of the hunting plot units.


2014 ◽  
Vol 13 (1) ◽  
pp. 68-71 ◽  
Author(s):  
Imad S. Khan ◽  
Travis R. Ladner ◽  
Komal F. Satti ◽  
Moneeb Ehtesham ◽  
Lori C. Jordan ◽  
...  

Cerebral sinus venous thrombosis (CSVT) is a relatively rare but potentially devastating disease. Medical management of CSVT with systemic anticoagulation has been the mainstay treatment strategy with these patients. However, some patients may not respond to this treatment or may present with very severe symptoms indicating more aggressive management strategies. The authors present the case of a pediatric patient who presented with severe CSVT, who underwent successful recanalization with endovascular tissue plasminogen activator (tPA) and abciximab. To the authors' knowledge there are no cases of endovascular thrombolysis for CSVT described in the literature in which abciximab has been used in conjunction with tPA. The authors also review the literature regarding the agents used and outcome in pediatric patients with CSVT after endovascular thrombolysis. The use of abciximab in conjunction with tPA may be considered in patients whose blood is hypercoagulable and in whom the treatment strategy is to obtain acute recanalization and long-term venous patency. However, the use of adjunctive agents increases the risk of hemorrhagic complications and must be done judiciously.


2018 ◽  
Author(s):  
Ruth E Brennan

The North Norfolk coast is a naturally eroding coastline that has been subject to various management strategies over time, many of which have impeded its natural evolution. The Kelling to Lowestoft-Ness Shoreline Management Plan underpins management of the North Norfolk coast, advocating policies of managed realignment and no active intervention for much of this coastline. Implementation of these policies would give rise to significant loss of housing in North Norfolk during the course of this century. This has caused intense conflict between local communities and coastal planners, with the former feeling abandoned to the vagaries of natural coastal processes. Coastal planners need to work closely with local communities to implement a long-term vision for a sustainable coast. The issues of conflicting land-use planning policies and compensation for affected communities must be addressed. The wider implications of current management strategies are not fully understood and may, in some cases, be unsustainable.


Author(s):  
Vimala Colaco ◽  
Harsha Sundaramurthy ◽  
Shasthara Paneyala ◽  
Nemichandra S. C.

Cerebral venous thrombosis (CVT) is an uncommon cause of stroke and is mainly a disease of the young. The aims of the study were to summarize the change in the clinical profile of CVT and provide an update regarding the current management of the same. A literature search was conducted using Pubmed and Google scholar using the desired terms. Studies were analysed and review was formulated. The median age of CVT in most studies was 32 years. There has been a shift from female pre-ponderence to equal gender predilection. Several studies are confirming the efficacy of D-dimer as a diagnostic marker of CVT. Newer oral anticoagulants have been found to be as efficient as warfarin. There have been several cases of CVT reported in association with COVID-19. This review confirmed the traditional understanding of age and risk factors of CVT. It also noted a change from the female pre-ponderence. NOACS are emerging as the preferred drug for the long-term management of CVT.


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