scholarly journals Ion concentrations in cerebrospinal fluid in wakefulness, sleep and sleep deprivation in healthy humans

2021 ◽  
Author(s):  
My Forsberg ◽  
Martin Olsson ◽  
Henrik Seth ◽  
Pontus Wasling ◽  
Henrik Zetterberg ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Sleep Deprivation ◽  
Ion Concentrations ◽  
Healthy Humans

scholarly journals Profiling of Cerebrospinal Fluid Lipids and Their Relationship with Plasma Lipids in Healthy Humans

Metabolites ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 268
Author(s):  
Kosuke Saito ◽  
Kotaro Hattori ◽  
Shinsuke Hidese ◽  
Daimei Sasayama ◽  
Tomoko Miyakawa ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Total Protein ◽  
Plasma Lipids ◽  
Plasma Lipid ◽  
Lipid Profiles ◽  
Brain Diseases ◽  
Lipid Homeostasis ◽  
Total Protein Content ◽  
Lipid Profiling ◽  
Healthy Humans

Lipidomics provides an overview of lipid profiles in biological systems. Although blood is commonly used for lipid profiling, cerebrospinal fluid (CSF) is more suitable for exploring lipid homeostasis in brain diseases. However, whether an individual’s background affects the CSF lipid profile remains unclear, and the association between CSF and plasma lipid profiles in heathy individuals has not yet been defined. Herein, lipidomics approaches were employed to analyze CSF and plasma samples obtained from 114 healthy Japanese subjects. Results showed that the global lipid profiles differed significantly between CSF and plasma, with only 13 of 114 lipids found to be significantly correlated between the two matrices. Additionally, the CSF total protein content was the primary factor associated with CSF lipids. In the CSF, the levels of major lipids, namely, phosphatidylcholines, sphingomyelins, and cholesterolesters, correlated with CSF total protein levels. These findings indicate that CSF lipidomics can be applied to explore changes in lipid homeostasis in patients with brain diseases.

scholarly journals Increased Cerebrospinal Fluid Amyloid-β During Sleep Deprivation in Healthy Middle-Aged Adults Is Not Due to Stress or Circadian Disruption

2020 ◽  
Vol 75 (2) ◽  
pp. 471-482 ◽  
Author(s):  
Margaret S. Blattner ◽  
Sunil K. Panigrahi ◽  
Cristina D. Toedebusch ◽  
Terry J. Hicks ◽  
Jennifer S. McLeland ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Sleep Deprivation ◽  
Amyloid Β ◽  
Circadian Disruption ◽  
Middle Aged ◽  
Middle Aged Adults

scholarly journals Cerebrospinal Fluid Corticotropin-Releasing Hormone in Healthy Humans: Effects of Yohimbine and Naloxone1

2000 ◽  
Vol 85 (11) ◽  
pp. 4138-4145
Author(s):  
Meena Vythilingam ◽  
George M. Anderson ◽  
Michael J. Owens ◽  
Thomas M. Halaszynski ◽  
J. Douglas Bremner ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Healthy Humans

scholarly journals Acute changes in Cerebrospinal Fluid 5-HIAA following Oral Paroxetine Challenge in Healthy Humans

2003 ◽  
Vol 28 (2) ◽  
pp. 339-347 ◽  
Author(s):  
Linda L Carpenter ◽  
George M Anderson ◽  
Jason M Siniscalchi ◽  
Phillip B Chappell ◽  
Lawrence H Price
Keyword(s):  
Cerebrospinal Fluid ◽  
Healthy Humans ◽  
Acute Changes

scholarly journals Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid

2009 ◽  
Vol 116 (3) ◽  
pp. 301-305 ◽  
Author(s):  
Dagmar Koethe ◽  
Daniela Schreiber ◽  
Andrea Giuffrida ◽  
Christian Mauss ◽  
Johannes Faulhaber ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Sleep Deprivation ◽  
Human Cerebrospinal Fluid

scholarly journals Increased cortical excitability after selective REM sleep deprivation in healthy humans: A transcranial magnetic stimulation study

2013 ◽  
Vol 14 (3) ◽  
pp. 288-292 ◽  
Author(s):  
Fabio Placidi ◽  
Silvana Zannino ◽  
Maria Albanese ◽  
Andrea Romigi ◽  
Francesca Izzi ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Sleep Deprivation ◽  
Rem Sleep ◽  
Magnetic Stimulation ◽  
Cortical Excitability ◽  
Rem Sleep Deprivation ◽  
Healthy Humans
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