Optimizing citric acid protocol to control implant‐related infections: An in vitro and in situ study

Author(s):  
Jairo M. Cordeiro ◽  
Júlia M. Pires ◽  
João G. S. Souza ◽  
Carolina V. Lima ◽  
Martinna M. Bertolini ◽  
...  
Keyword(s):  
2017 ◽  
Vol 51 (2) ◽  
pp. 141-148 ◽  
Author(s):  
C.V. da Silva ◽  
T.M. Ramos-Oliveira ◽  
T.F. Mantilla ◽  
P.M. de Freitas

Although several studies have demonstrated the efficacy of AmF/NaF/SnCl2 solution in inhibiting dental erosion progression, measures for further improvement in its effectiveness are paramount. Thus, this in situ study evaluated whether the protective effect promoted by the AmF/NaF/SnCl2 solution would be enhanced by increasing its frequency of use. The study was conducted with 12 volunteers, a 4-phase (5 days each) randomized, crossover model. Extraoral erosive challenges (0.5% citric acid, pH 2.6, 6 × 2 min/day) and rinsing protocol (1 or 2 × 2 min/day) were performed. Before the in situ phase, human enamel samples were subjected to an in vitro surface softening (1% citric acid, pH 4.0, for 3 min). Four treatment protocols were tested using samples in replicas (n = 12): group G1 - deionized water (negative control); G2 - NaF solution (positive control, 500 ppm F-, pH 4.5); G3 - AmF/NaF/SnCl2 solution (500 ppm F-, 800 ppm Sn2+, pH 4.5) once a day; G4 - AmF/NaF/SnCl2 solution twice a day. Tissue loss and morphological changes were determined by optical profilometry (n = 12) and scanning electron microscopy (n = 3) analysis, respectively. Data were statistically analyzed by ANOVA with subsequent pairwise comparison of treatments. Tissue loss means (±SD in µm) for each treatment protocol and statistical differences were found as follows: G1 4.55 ± 2.75, G2 4.59 ± 2.13, G3 2.64 ± 1.55, and G4 1.34 ± 1.16. Although there was no difference between the 2 AmF/NaF/SnCl2 solution application regimens (once or twice a day), application of the product twice a day was the only treatment that was able to control erosion progression, differing from the control groups.


2008 ◽  
Vol 33 (1) ◽  
pp. 35-37 ◽  
Author(s):  
Esber Çaglar ◽  
Sule Kavaloglu Cildir ◽  
Nuket Sandalli

Objectives: Whereas the potential effect of acidic drinks in the etiology of dental erosion is well recognized the role of malt drinks is unclear. The primary aim of the present study was to compare the in vitro erosive effect on enamel produced by different aromated malt drinks. A secondary objective was to compare their erosive effects in situ with those determined in vitro. Materials and methods: To select the malt drink for the study in situ, six commercially available malt drinks were examined for erosive potential in vitro. The study in situ was a single centre, 2-period, 2-treatment crossover study to compare the erosive effect of a commercially available malt drink (Test), with that of natural spring water (Control), over 10 day periods on 10 healthy volunteers. Subjects wore upper removable appliances containing two human enamel specimens from 9 a.m. to 4 p.m. The regimen of intake of the drinks was 250 ml at midday. Measurements of enamel loss were made on samples after 5 and 10 days by profilometry. Results: The in situ study showed a statistically significant difference in erosive potential between the test and control beverages. No specimen exposed to the control beverage displayed appreciable erosion. Erosion occurred with the test drink, but to a variable degree between subjects. Conclusions: Malt drinks should be considered as potentially erosive as the results for enamel specimens exposed to the test beverage in the clinical study showed a degree of erosion that varied greatly between different participants. It is likely that under these conditions an increase in the degree of erosion would be observed in children and young people who consume malt drinks.


2021 ◽  
Vol 35 ◽  
Author(s):  
Maria Denise Rodrigues DE MORAES ◽  
Vanara Florêncio PASSOS ◽  
Gislaine Cristina PADOVANI ◽  
Lady Clarissa Brito da Rocha BEZERRA ◽  
Ilka Maria VASCONCELOS ◽  
...  

2017 ◽  
Vol 28 (3) ◽  
pp. 337-345
Author(s):  
Taís Fonseca Mantilla ◽  
Cecilia Pedroso Turssi ◽  
Thayanne Monteiro Ramos-Oliveira ◽  
Camila Vieira da Silva ◽  
Luis Cláudio Suzuki ◽  
...  

Abstract Erosion incidence is increasing and its control is still a challenge in clinical practice. This study evaluated 4% TiF4-gel effects on eroded human dentin subjected to in situ erosive/abrasive episodes. Seventy-two previously eroded dentin slabs (0.05 M citric acid, pH 2.3, 20 min) were allocated to 6 groups (n=12) according to the treatment to be performed during the in situ phase and number of erosive/abrasive cycles, as follows: 4% TiF4-gel applied once (TiF41), twice (TiF42) or three times (TiF43) followed by 1, 2 and 3 erosive/abrasive cycles, respectively. Gel was applied before the beginning of the next cycle. Control groups were subjected to 1 (C1), 2 (C2) and 3 (C3) erosive/abrasive cycles only. A seventh group (n=12) comprised in vitro uneroded samples (UN) subjected to 3 erosive/abrasive cycles. Each cycle corresponded to 2 days of erosive (citric acid 0.5%, pH 2.6, 6x/day) and abrasive (electric toothbrush, 10 s/sample, 1 x/day) challenges. Samples were evaluated under profilometry and environmental scanning electron microscopy (ESEM). Atomic force microscopy images (AFM) were also made (n=3). Repeated measures 2-way ANOVA and Tukey test (p<0.001) showed that TiF42, which did not differ from TiF41 and TiF43, revealed a significant reduction in surface loss compared to all control groups. TiF41 and TiF43 showed no significant difference from C1, but both groups demonstrated significantly smaller surface loss than C2 and C3. ESEM and AFM micrographs suggested alterations on treated surfaces compared to samples from control groups, showing reduced diameters of dentinal tubules lumens. Therefore, TiF4 was able to reduce the progression of erosive/abrasive lesions.


2015 ◽  
Vol 43 (9) ◽  
pp. 1154-1161 ◽  
Author(s):  
Marília Zeczkowski ◽  
Livia Maria Andaló Tenuta ◽  
Gláucia Maria Bovi Ambrosano ◽  
Flávio Henrique Baggio Aguiar ◽  
Débora Alves Nunes Leite Lima

2009 ◽  
Vol 43 (4) ◽  
pp. 302-307 ◽  
Author(s):  
M.H. Spiguel ◽  
M.F. Tovo ◽  
P.F. Kramer ◽  
K.S. Franco ◽  
K.M.R.P. Alves ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document