scholarly journals In vivoelectrical application on titanium implants stimulating bone formation

2016 ◽  
Vol 52 (3) ◽  
pp. 479-484 ◽  
Author(s):  
L. M. Bins-Ely ◽  
E. B. Cordero ◽  
J. C. M. Souza ◽  
W. Teughels ◽  
C. A. M. Benfatti ◽  
...  
Keyword(s):  
Bone Formation ◽  
Titanium Implants

scholarly journals In Vivo Study for Clinical Application of Dental Stem Cell Therapy Incorporated with Dental Titanium Implants

Materials ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 381
Author(s):  
Hyunmin Choi ◽  
Kyu-Hyung Park ◽  
Narae Jung ◽  
June-Sung Shim ◽  
Hong-Seok Moon ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Formation ◽  
Alveolar Bone ◽  
Human Mesenchymal Stem Cells ◽  
Titanium Implants ◽  
Osteogenic Potential ◽  
Induction Medium ◽  
Radiographic Analysis ◽  
New Bone Formation

The aim of this study was to investigate the behavior of dental-derived human mesenchymal stem cells (d-hMSCs) in response to differently surface-treated implants and to evaluate the effect of d-hMSCs on local osteogenesis around an implant in vivo. d-hMSCs derived from alveolar bone were established and cultured on machined, sandblasted and acid-etched (SLA)-treated titanium discs with and without osteogenic induction medium. Their morphological and osteogenic potential was assessed by scanning electron microscopy (SEM) and real-time polymerase chain reaction (RT-PCR) via mixing of 5 × 106 of d-hMSCs with 1 mL of Metrigel and 20 μL of gel-cell mixture, which was dispensed into the defect followed by the placement of customized mini-implants (machined, SLA-treated implants) in New Zealand white rabbits. Following healing periods of 2 weeks and 12 weeks, the obtained samples in each group were analyzed radiographically, histomorphometrically and immunohistochemically. The quantitative change in osteogenic differentiation of d-hMSCs was identified according to the type of surface treatment. Radiographic analysis revealed that an increase in new bone formation was statistically significant in the d-hMSCs group. Histomorphometric analysis was in accordance with radiographic analysis, showing the significantly increased new bone formation in the d-hMSCs group regardless of time of sacrifice. Human nuclei A was identified near the area where d-hMSCs were implanted but the level of expression was found to be decreased as time passed. Within the limitations of the present study, in this animal model, the transplantation of d-hMSCs enhanced the new bone formation around an implant and the survival and function of the stem cells was experimentally proven up to 12 weeks post-sacrifice.

Effect of RGD peptide coating of titanium implants on periimplant bone formation in the alveolar crest

2002 ◽  
Vol 13 (3) ◽  
pp. 312-319 ◽  
Author(s):  
Henning Schliephake ◽  
Dieter Scharnweber ◽  
Michael Dard ◽  
Sophie Rößler ◽  
Andreas Sewing ◽  
...  
Keyword(s):  
Bone Formation ◽  
Rgd Peptide ◽  
Titanium Implants ◽  
Alveolar Crest ◽  
Peptide Coating

scholarly journals Application of Laser-Induced Bone Therapy by Carbon Dioxide Laser Irradiation in Implant Therapy

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Takahiro Naka ◽  
Satoshi Yokose
Keyword(s):  
Bone Formation ◽  
Laser Irradiation ◽  
Healing Process ◽  
Titanium Implants ◽  
Control Group ◽  
Sham Operation ◽  
Micro Ct ◽  
Rat Tibia ◽  
Implant Therapy ◽  
Laser Group

This study evaluated the application of laser-induced bone therapy (LIBT) to reduce implant healing time in rat tibia. Twenty 10-week-old female Sprague-Dawlay rats were used. The rats received laser irradiation (laser group) or sham operation (control group) on either side of the tibia. Five days after invasion, titanium implants were inserted in proximal tibia. Five, 10, and 20 days after implant placement, tibiae were collected. After taking micro-CT and performing a torque test, the tibiae were decalcified and 8-μm-thick sections were prepared. Specimens were stained with hematoxylin and eosin.Results. Micro-CT images, removal torque values, and histomorphometric analysis data demonstrated a significantly accelerated bone formation in the laser group earlier in the healing process.Conclusion. The use of laser irradiation was effective in promoting bone formation and acquiring osseointegration of titanium implants inserted in rat tibia. LIBT may be suitable for use in implant therapy.

Hydroxyapatite nanoparticles in poly-D,L-lactic acid coatings on porous titanium implants conducts bone formation

2010 ◽  
Vol 95A (3) ◽  
pp. 665-672 ◽  
Author(s):  
Thomas Jensen ◽  
Thomas Jakobsen ◽  
Jørgen Baas ◽  
Jens V. Nygaard ◽  
Alireza Dolatshahi-Pirouz ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Bone Formation ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Hydroxyapatite Nanoparticles

scholarly journals Bone formation enhanced by induction: Bone growth in titanium implants in rats

1985 ◽  
Vol 56 (1) ◽  
pp. 67-71 ◽  
Author(s):  
Helge Rønningen ◽  
Ludvig F. Solheim ◽  
Norvald Langeland
Keyword(s):  
Bone Formation ◽  
Bone Growth ◽  
Titanium Implants

Direct current influence on bone formation in titanium implants

Biomaterials ◽  
1984 ◽  
Vol 5 (6) ◽  
pp. 341-346 ◽  
Author(s):  
F. Buch ◽  
T. Albrektsson ◽  
E. Herbst
Keyword(s):  
Bone Formation ◽  
Direct Current ◽  
Titanium Implants

Bone formation at rhBMP-2-coated titanium implants in the rat ectopic model

2007 ◽  
Vol 34 (5) ◽  
pp. 444-451 ◽  
Author(s):  
Jan Hall ◽  
Rachel G. Sorensen ◽  
John M. Wozney ◽  
Ulf M.E. Wikesjö
Keyword(s):  
Bone Formation ◽  
Titanium Implants
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