Dietary linseed oil in the maternal diet affects immunoglobulins, tissue fatty acid composition and expression of lipid metabolism-related genes in piglets

2016 ◽  
Vol 101 (5) ◽  
pp. e257-e265 ◽  
Author(s):  
X. L. Chen ◽  
N. Wang ◽  
M. L. Tian ◽  
L. Wang ◽  
T. Liu ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Lipid Metabolism ◽  
Acid Composition ◽  
Linseed Oil ◽  
Maternal Diet ◽  
Tissue Fatty Acid Composition ◽  
Tissue Fatty Acid

Adipose tissue fatty acid composition and cognitive impairment

Nutrition ◽  
2018 ◽  
Vol 54 ◽  
pp. 153-157 ◽  
Author(s):  
Frej Stilling ◽  
Alicja Wolk ◽  
Dorota Religa ◽  
Jerzy Leppert ◽  
Leif Bergkvist ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Fatty Acid Composition ◽  
Cognitive Impairment ◽  
Fatty Acid ◽  
Acid Composition ◽  
Tissue Fatty Acid Composition ◽  
Adipose Tissue Fatty Acid ◽  
Tissue Fatty Acid

scholarly journals Effects of dietary n -6: n -3 PUFA ratio on the growth performance, serum lipid and adipokine profiles, tissue fatty acid composition and gene expression of lipid metabolism of finishing pigs

2020 ◽  
Author(s):  
Jing Chen ◽  
Jiantao Li ◽  
Xianjun Liu ◽  
Hongze Cui ◽  
Liyan Wang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Lipid Metabolism ◽  
Growth Performance ◽  
Acid Composition ◽  
Blood Lipid ◽  
Finishing Pigs ◽  
Pufa Ratio ◽  
Tissue Fatty Acid Composition

Abstract Background The health benefits of n-3 polyunsaturated fatty acids (PUFA), such as cardioprotective, anti-inflammatory and hypo-triglyceridemic properties, have been well documented. However, current dietary modification can easily lead to excessive concentrations of n-6 PUFA and an imbalance in the n-6:n-3 PUFA ratio, resulting in the pathogenesis of obesity and related diseases. This study investigated the effects of various dietary n-6:n-3 PUFA ratios on the growth performance, blood lipid and cytokine profiles, tissue fatty acid composition, and gene expression involved in lipid metabolism in finishing pigs. Seventy-two crossbred [(Duroc × Landrace) × Yorkshire] finishing pigs (68.5 ± 1·8 kg) were fed one of four isoenergetic diets with n-6:n-3 PUFA ratios of 2:1, 3:1, 5:1 and 8:1. Results Pigs fed diets with n-6:n-3 PUFA ratios of 3:1 and 5:1 had a higher average daily gain (ADG) and average daily feed intake (ADFI) (P < 0.05) and a lower feed conversion ratio (FCR) (P < 0.05). The concentrations of triglyceride (TG) and total cholesterol (TC) of pigs fed diets with n-6:n-3 PUFA ratios of 1:1 to 5:1 decreased (P < 0·05), whereas the ratio of concentrations of high-density to low-density lipoprotein cholesterol (HDL-C:LDL-C) in pigs fed a diet with an n-6:n-3 PUFA ratio of 2:1 increased (P < 0·05) compared with those fed a diet with an n-6:n-3 PUFA ratio of 8:1. Pigs fed a diet with n-6:n-3 PUFA ratios of 2:1 and 3:1 had lower concentrations of leptin (LEP) and interleukin 6 (IL-6) (P < 0·05), and higher concentrations of adiponectin (APN) (P < 0·05) than those fed diets with n-6:n-3 PUFA ratios of 5:1 and 8:1. Diets with n-6:n-3 PUFA ratios of 2:1 and 3:1 markedly down-regulated the expression levels of peroxisome proliferator-activated receptor-γ (PPARγ) and lipoprotein lipase (LPL) in both the longissimus dorsi muscle (LM) and subcutaneous adipose tissue (SCAT), but up-regulated the expression level of adipocyte fatty acid binding protein (aP2) in the LM. The expression levels of aP2 and hormone- sensitive lipase were similar to those of PPARγ in the SCAT. Conclusions This study demonstrated that dietary n-6:n-3 PUFA ratios between 3:1 and 5:1 beneficially affected growth performance, optimize blood lipid and adipocytokine levels, enhanced absorption and deposition of n-3 PUFA and regulated lipid metabolism-related genes.

Prostate cancer vs hyperplasia: relationships with prostatic and adipose tissue fatty acid composition

2002 ◽  
Vol 66 (5-6) ◽  
pp. 467-477 ◽  
Author(s):  
G. Mamalakis ◽  
A. Kafatos ◽  
N. Kalogeropoulos ◽  
N. Andrikopoulos ◽  
G. Daskalopulos ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Adipose Tissue ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Tissue Fatty Acid Composition ◽  
Adipose Tissue Fatty Acid ◽  
Tissue Fatty Acid
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