Selenium-enrichedSaccharomyces cerevisiaeimproves growth, antioxidant status and selenoprotein gene expression in Arbor Acres broilers

2016 ◽  
Vol 101 (2) ◽  
pp. 259-266 ◽  
Author(s):  
F. Chen ◽  
L. Zhu ◽  
H. Qiu ◽  
S. Qin
Keyword(s):  
Gene Expression ◽  
Antioxidant Status ◽  
Selenoprotein Gene

Effect of benzoyl peroxide on antioxidant status, NF-κB activity and interleukin-1α gene expression in human keratinocytes

Toxicology ◽  
2001 ◽  
Vol 165 (2-3) ◽  
pp. 225-234 ◽  
Author(s):  
Giuseppe Valacchi ◽  
Gerald Rimbach ◽  
Claude Saliou ◽  
Stefan U Weber ◽  
Lester Packer
Keyword(s):  
Gene Expression ◽  
Benzoyl Peroxide ◽  
Antioxidant Status ◽  
Human Keratinocytes ◽  
Interleukin 1Α

scholarly journals Gene Expression Profile of Colon Mucosa after Cytotoxic Insult in wt and Apc-Mutated Pirc Rats: Possible Relation to Resistance to Apoptosis during Carcinogenesis

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Angelo Pietro Femia ◽  
Cristina Luceri ◽  
Maura Lodovici ◽  
Stefania Crucitta ◽  
Giovanna Caderni
Keyword(s):  
Gene Expression ◽  
Gene Expression Profile ◽  
Expression Profile ◽  
Antioxidant Status ◽  
Genotoxic Stress ◽  
Rt Pcr ◽  
Induced Genes ◽  
Stress Related Genes ◽  
Microarray Technique ◽  
Unsupervised Cluster Analysis

Apc-mutated Pirc rats, spontaneously developing intestinal tumours, are resistant to 1,2-dimethylhydrazine- (DMH-) induced colon apoptosis. To understand this phenomenon, we analyzed the expression of genotoxic stress-related genes Mgmt, Gsta1, and Gstp1 in the colon of wt and Pirc rats in basal conditions and 24 h after DMH; plasmatic oxidant/antioxidant status was also evaluated. After DMH, Mgmt expression was increased in both genotypes but significantly only in wt rats; Gsta1 expression was significantly increased in both genotypes. Gstp1 expression did not vary after DMH but was lower in Pirc rats. Moreover, for each genotype, we studied by microarray technique whole gene expression profile after DMH. By unsupervised cluster analysis, 28 genes were differentially modulated between the two genotypes. Among them were interferon-induced genes Irf7, Oas1a, Oasl2, and Isg15 and the transcription factor Taf6l, overexpressed in DMH-treated wt rats and unchanged in Pirc rats. RT-PCR confirmed their overexpression in DMH-treated wt rats and showed a slighter variation in DMH-treated Pirc rats. Taken together, despite a blunted induction of Irf7, Oas1a, and Mgmt, defective apoptosis in Pirc rats 24 h after DMH is not mirrored by major differences in gene expression compared with wt rats.

Selenoprotein gene expression during selenium-repletion of selenium-deficient rats

1996 ◽  
Vol 51 (3) ◽  
pp. 211-223 ◽  
Author(s):  
Giovanna Bermano ◽  
Fergus Nicol ◽  
John A. Dyer ◽  
Roger A. Sunde ◽  
Geoffrey J. Beckett ◽  
...  
Keyword(s):  
Gene Expression ◽  
Selenoprotein Gene
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