Incidence of allergen‐specific and total immunoglobulin E positivity in children undergoing adenotonsillectomy

2021 ◽  
Author(s):  
Matthew E Lam ◽  
Leon Kitipornchai ◽  
Natelle Ball ◽  
Lernik Sarkissian ◽  
Terry Sands ◽  
...  
Keyword(s):  
Immunoglobulin E ◽  
Total Immunoglobulin

scholarly journals The Relationship of Serum Antigen-Specific and Total Immunoglobulin E with Adult Cardiovascular Diseases

2018 ◽  
Vol 15 (11) ◽  
pp. 1098-1104 ◽  
Author(s):  
Zhiyan Xu ◽  
Tao Wang ◽  
Xiaoxiao Guo ◽  
Yao Li ◽  
Yi Hu ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Immunoglobulin E ◽  
Serum Antigen ◽  
Relationship Of ◽  
The Relationship ◽  
Total Immunoglobulin

Correlation between Total Serum Immunoglobulin E (IgE) and Absolute Eosinophil Count (AEC) in Allergic Diseases In Children

2020 ◽  
Vol 7 (1) ◽  
pp. 5-9
Author(s):  
Dr. Mayank Surana ◽  
Dr. Vineeta Pande ◽  
Dr. Sharad Agarkhedkar ◽  
Dr. Ajit Teegala
Keyword(s):  
Atopic Dermatitis ◽  
Bronchial Asthma ◽  
Eosinophil Count ◽  
Immunoglobulin E ◽  
Allergic Diseases ◽  
Total Ige ◽  
Serum Ige ◽  
Absolute Eosinophil Count ◽  
Serum Total Ige ◽  
Total Immunoglobulin

Allergy, is a clinical expression of soluble factors like IgE, histamine or eosinophils found in serum or plasma of such patients. The products that are responsible for allergy are called as Allergens. Allergens normally induce IgE production which leads to type 1 hypersensitivity response on subsequent exposure to the same allergen. The target organs are mostly nose, lung, skin and gastrointestinal tract. Atopy is also considered as a triad of Atopic dermatitis, allergic rhinitis and bronchial asthma. Raised serum IgE and AEC are proven indicators of allergic phenomenon. Various studies show relationship between serum Immunoglobulin E level and total eosinophil count in population suffering from allergic diseases. Serum total Immunoglobulin E, total eosinophil count and specific IgE are all helpful for the diagnosis and treatment of allergic diseases. Objectives: 1.To Evaluate Serum Total IgE level in Children with allergic diseases.2. To Evaluate Absolute Eosinophil Count (AEC) in children with allergic diseases.3. To Correlate Serum Total Immunoglobulin E Level and Absolute Eosinophil Count (AEC) with allergic diseases. Methodology: Cross sectional study with 100 children in the age group 2-12 years with nasopharyngeal allergies (like bronchial asthma and atopic rhinitis) and skin allergies (like atopic dermatitis, urticaria) ,eye allergies were enrolled and serum IgE levels and AEC levels was done. Results: In present study Absolute eosinophil count was raised in 58% of cases Serum IgE was raised in 54% of cases. In present study, of 58% cases with raised Absolute eosinophil count 81% (47 cases) showed raised serum IgE levels. Conclusion: Absolute eosinophil count and serum Total IgE has been considered as a significant marker of allergic state and can be used as a marker of allergic response in atopic individuals. Raised serum IgE and AEC are more in nasobronchial allergy as compare to other systemic allergies. The elevated level of serum Total IgE and Absolute Eosinophil Count both shows Significant Correlation thus can be considered as a dependable laboratory investigation in diagnosing and categorizing allergic diseases.

scholarly journals DNA methylation and serum total immunoglobulin E (IgE) levels: a methylome-wide association study in adults with asthma

2018 ◽  
Author(s):  
Sebastien Chanoine ◽  
Anaïs Malpertuis ◽  
Laura Beaumier ◽  
Dylan Aïssi ◽  
Emmanuelle Bouzigon ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Association Study ◽  
Immunoglobulin E ◽  
Total Immunoglobulin
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