Mediator of DNA damage checkpoint protein 1 (MDC1) as a prognostic marker for patients with oral squamous cell carcinoma

2017 ◽  
Vol 46 (4) ◽  
pp. 253-258 ◽  
Author(s):  
Jigna Harshadbhai Dave ◽  
Hemangini Hasit Vora ◽  
Nandita Radhabinod Ghosh ◽  
Trupti Indravadan Trivedi
Keyword(s):  
Dna Damage ◽  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Prognostic Marker ◽  
Squamous Cell ◽  
Dna Damage Checkpoint ◽  
Checkpoint Protein

scholarly journals Association between the C-reactive protein/albumin ratio and prognosis in patients with oral squamous cell carcinoma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kenji Yamagata ◽  
Satoshi Fukuzawa ◽  
Naomi Ishibashi-Kanno ◽  
Fumihiko Uchida ◽  
Hiroki Bukawa
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Prognostic Marker ◽  
Squamous Cell ◽  
Inflammatory Markers ◽  
Outcome Variable ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Significant Difference

AbstractThe systemic inflammatory response is known to be associated with poor outcomes in patients with various types of cancer. The C-reactive protein (CRP)/albumin (Alb) ratio (CAR) has been reported as a novel inflammation-based prognostic marker. We have evaluated the prognostic value of inflammatory markers for patients with oral squamous cell carcinoma (OSCC). The study population included 205 patients treated with OSCC between 2013 and 2018. The primary predictor variable was the inflammatory markers. The primary outcome variable was overall survival (OS). Univariate and multivariate analyses were performed using a Cox proportional hazards model to identify independent prognostic factors. The CAR had the highest area under the curve (AUC) values compared with other markers in the receiver operating characteristic (ROC) curve analysis. The cutoff value for CAR was 0.032 (AUC 0.693, P < 0.001). There was a significant difference in OS when patients were stratified according to CAR, with 79.1% for CAR < 0.032 and 35% for CAR ≥ 0.032 (P < 0.001). Cox multivariate analysis identified independent predictive factors for OS: age (hazard ratio [HR] 2.155, 95% confidence interval [CI] 1.262–3.682; P = 0.005), stage (HR 3.031, 95% CI 1.576–5.827; P = 0.001), and CAR (HR 2.859, 95% CI 1.667–4.904; P < 0.001). CAR (≥ 0.032 vs. < 0.032) is a good prognostic marker in patients with OSCC in terms of age and stage.

scholarly journals Correction: Tissue and serum expression of TGM-3 may be prognostic marker in patients of oral squamous cell carcinoma undergoing chemo-radiotherapy

PLoS ONE ◽  
2018 ◽  
Vol 13 (8) ◽  
pp. e0202432
Author(s):  
Seema Nayak ◽  
M. L. B. Bhatt ◽  
Madhu Mati Goel ◽  
Seema Gupta ◽  
Abbas Ali Mahdi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Prognostic Marker ◽  
Squamous Cell

Cortactin is a prognostic marker for oral squamous cell carcinoma and its overexpression is involved in oral carcinogenesis

2016 ◽  
Vol 32 (3) ◽  
pp. 799-812 ◽  
Author(s):  
Yu-Ching Liu ◽  
Heng-Chien Ho ◽  
Miau-Rong Lee ◽  
Chung-Min Yeh ◽  
Hsien-Chang Tseng ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Prognostic Marker ◽  
Squamous Cell ◽  
Oral Carcinogenesis

Expression status of Zic family member 2 as a prognostic marker for oral squamous cell carcinoma

2009 ◽  
Vol 136 (4) ◽  
pp. 553-559 ◽  
Author(s):  
Kentaro Sakuma ◽  
Atsushi Kasamatsu ◽  
Masanobu Yamatoji ◽  
Yukio Yamano ◽  
Kazuaki Fushimi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Family Member ◽  
Prognostic Marker ◽  
Squamous Cell ◽  
Expression Status

Decreased GRP78 Protein Expression is a Potential Prognostic Marker of Oral Squamous Cell Carcinoma in Taiwan

2010 ◽  
Vol 109 (5) ◽  
pp. 326-337 ◽  
Author(s):  
Tze-Ta Huang ◽  
Jeff Yi-Fu Chen ◽  
Chih-En Tseng ◽  
Yu-Chieh Su ◽  
Hsu-Chueh Ho ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Protein Expression ◽  
Cell Carcinoma ◽  
Prognostic Marker ◽  
Squamous Cell
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