Successful use of fetoscopic laser surgery as treatment for a monochorionic‐triamniotic triplet pregnancy complicated by twin‐reversed arterial perfusion sequence and severe selective fetal growth restriction: A case report

2019 ◽  
Vol 45 (8) ◽  
pp. 1584-1587
Author(s):  
Mayumi Takano ◽  
Masahiko Nakata ◽  
Takayuki Rikitake ◽  
Sumito Nagasaki ◽  
Eijiro Hayata ◽  
...  
Keyword(s):  
Case Report ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Laser Surgery ◽  
Growth Restriction ◽  
Triplet Pregnancy ◽  
Arterial Perfusion ◽  
Twin Reversed Arterial Perfusion

scholarly journals Potential effects of transdermal nitric oxide donor on fetal growth restriction and oligohydramnios: A case report

2020 ◽  
Vol 8 (12) ◽  
pp. 3288-3293
Author(s):  
Tsuyoshi Murata ◽  
Toma Fukuda ◽  
Tetsu Sato ◽  
Aya Kanno ◽  
Hyo Kyozuka ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Case Report ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Growth Restriction ◽  
Nitric Oxide Donor

Advanced tubal pregnancy associated with severe fetal growth restriction: a case report

2003 ◽  
Vol 13 (6) ◽  
pp. 422-425 ◽  
Author(s):  
T. Radaelli ◽  
G. Bulfamante ◽  
I. Cetin ◽  
A. M. Marconi ◽  
G. Pardi
Keyword(s):  
Case Report ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Tubal Pregnancy ◽  
Growth Restriction

scholarly journals Maternal sirolimus therapy and fetal growth restriction

2021 ◽  
Vol 8 (2) ◽  
pp. 19-24
Author(s):  
Sangay Tshering ◽  
Namkha Dorji ◽  
Youden Sonam
Keyword(s):  
Case Report ◽  
Signaling Pathway ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Mtor Signaling ◽  
Growth Restriction ◽  
Mtor Signaling Pathway ◽  
Epigenetic Modulation ◽  
In Pregnancy

Fetal growth restriction associated with continued maternal sirolimus therapy in pregnancy has not been reported. We hereby present a case of maternal sirolimus therapy resulting in fetal growth restriction and propose a multi-hit model. This hypothetic model is based on inhibition of mTOR signaling pathway and epigenetic modulation. This case report adds to the paucity of literature on continued monotherapeutic maternal sirolimus in pregnancy and its adverse fetal effects.

scholarly journals Twin-Twin Transfusion Syndrome with and without Selective Fetal Growth Restriction Prior to Fetoscopic Laser Surgery: Short and Long-Term Outcome

2019 ◽  
Vol 8 (7) ◽  
pp. 969 ◽  
Author(s):  
Groene ◽  
Tollenaar ◽  
van Klink ◽  
Haak ◽  
Klumper ◽  
...  
Keyword(s):  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Laser Surgery ◽  
Growth Restriction ◽  
Separate Analysis ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Short And Long Term ◽  
Perinatal Survival

As twin-twin transfusion syndrome (TTTS) and selective fetal growth restriction (sFGR) are both prevalent complications of monochorionic (MC) twin pregnancies, its coexistence is not uncommon. The aim of this study is to evaluate the short and long-term outcome in TTTS with and without sFGR prior to fetoscopic laser coagulation. All TTTS cases treated with laser surgery at our center between 2001–2019 were retrospectively reviewed for the presence of sFGR, defined as an estimated fetal weight (EFW) <10th centile. We compared two groups: TTTS-only and TTTS + sFGR. Primary outcomes were perinatal survival and long-term severe neurodevelopmental impairment (NDI). Of the 527 pregnancies eligible for analysis, 40.8% (n = 215) were categorized as TTTS-only and 59.2% (n = 312) as TTTS + sFGR. Quintero stage at presentation was higher in the TTTS + sFGR group compared to the TTTS-only group (57% compared to 44% stage III). Separate analysis of donors showed significantly lower perinatal survival for donors in the TTTS + sFGR group (72% (224/311) compared to 81% (173/215), p = 0.027). Severe NDI at follow-up in long-term survivors in the TTTS-only and TTTS + sFGR group was present in 7% (13/198) and 9% (27/299), respectively (p = 0.385). Both sFGR (OR 1.5;95% CI 1.1–2.0, p = 0.013) and lower gestational age at laser (OR 1.1;95% CI 1.0–1.1, p = 0.001) were independently associated with decreased perinatal survival. Thus, sFGR prior to laser surgery is associated with a more severe initial presentation and decreased donor perinatal survival. The long-term outcome was not affected.

scholarly journals Case report: Klippel-Trenaunay-Weber syndrome associated with fetal growth restriction

1996 ◽  
Vol 11 (11) ◽  
pp. 2544-2545 ◽  
Author(s):  
G. Fait ◽  
Y. Daniel ◽  
M.J. Kupfenninc ◽  
I. Gull ◽  
M.R. Peyser ◽  
...  
Keyword(s):  
Case Report ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Growth Restriction ◽  
Weber Syndrome

scholarly journals Endoscopic Placental Laser Coagulation in Monochorionic Diamniotic Twins with Type II Selective Fetal Growth Restriction

2015 ◽  
Vol 38 (2) ◽  
pp. 86-93 ◽  
Author(s):  
Gergana Peeva ◽  
Sarah Bower ◽  
Laszlo Orosz ◽  
Petya Chaveeva ◽  
Ranjit Akolekar ◽  
...  
Keyword(s):  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Laser Surgery ◽  
Cervical Length ◽  
Growth Restriction ◽  
Ductus Venosus ◽  
Laser Coagulation ◽  
Multivariable Logistic Regression Analysis ◽  
Type Ii ◽  
Discharge From Hospital

Objective: To determine predictors of survival in monochorionic diamniotic twins with selective fetal growth restriction type II (sFGR-II), with or without twin-to-twin transfusion syndrome (TTTS), treated by endoscopic placental laser coagulation. Methods: Laser surgery was performed at 20 (15-27) weeks' gestation in 405 cases of sFGR-II with and 142 without coexisting TTTS. Multivariable logistic regression analysis was performed to determine significant predictors of survival to discharge from hospital. Results: There was survival of the small twin in 216 (39.5%) and of the large twin in 379 (69.3%) cases. Significant predictors of survival of both the small and larger twin were ductus venosus Doppler findings in the small twin, gestational age at laser and cervical length, but not the presence of TTTS or Doppler findings in the large twin. Conclusions: In sFGR-II, survival after laser surgery is primarily dependent on the condition of the small twin.

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