Psychological effects of fetal diagnoses of non-lethal congenital anomalies on the experience of pregnant women during the remainder of their pregnancy

2014 ◽  
Vol 41 (1) ◽  
pp. 77-83 ◽  
Author(s):  
Vitaya Titapant ◽  
Prakong Chuenwattana
Keyword(s):  
Pregnant Women ◽  
Congenital Anomalies ◽  
Psychological Effects

scholarly journals Exposure to misoprostol and hormones during pregnancy and risk of congenital anomalies

2008 ◽  
Vol 24 (6) ◽  
pp. 1447-1453 ◽  
Author(s):  
Tatiane da Silva Dal Pizzol ◽  
Maria Teresa Vieira Sanseverino ◽  
Sotero Serrate Mengue
Keyword(s):  
Logistic Regression ◽  
Health System ◽  
Pregnant Women ◽  
Sex Hormones ◽  
National Health ◽  
Congenital Anomalies ◽  
National Health System ◽  
Positive Association ◽  
Brazilian State ◽  
Study Center

This study evaluated the association between use of misoprostol and other drugs to induce menstruation, and congenital anomalies. A sample of 4,856 pregnant women 20 years and older were enrolled consecutively in prenatal services in the Unified National Health System, in six Brazilian State capitals. Data on socio-demographics and use of medicines were obtained using an interview from the 21st to 28th week of pregnancy. Other data, including information on delivery and diagnosis of congenital anomalies by the attending neonatal physician were obtained from patient charts. Potential confounders were adjusted by logistic regression. Use of drugs to induce menstruation was reported by 707 women (14.6%), of whom 120 (17%) reported use of misoprostol. After adjusting for the study center, a positive association was observed between misoprostol and congenital anomalies (OR = 2.64; 95%CI: 1.03-6.75); a positive association was also observed for sex hormones (OR = 2.24; 95%CI: 1.06-4.74). The results suggest that the use of misoprostol or sex hormones during pregnancy increases the risk of congenital anomalies.

scholarly journals Trends in resource use and effectiveness of ultrasound detection of fetal structural anomalies in France: a multiple registry-based study

BMJ Open ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. e025482 ◽  
Author(s):  
Clément Ferrier ◽  
Ferdinand Dhombres ◽  
Babak Khoshnood ◽  
Hanitra Randrianaivo ◽  
Isabelle Perthus ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Pregnant Women ◽  
Outcome Measures ◽  
Resource Use ◽  
Congenital Anomalies ◽  
Ultrasound Screening ◽  
Healthcare Database ◽  
Prenatal Detection ◽  
Two Samples ◽  
Over Time

ObjectiveTo analyse trends in the number of ultrasound examinations in relation to the effectiveness of prenatal detection of birth defects using population-based data in France.DesignA multiple registry-based study of time trends in resource use (number of ultrasounds) and effectiveness (proportion of cases prenatally diagnosed).SettingThree registries of congenital anomalies and claims data on ultrasounds for all pregnant women in France.ParticipantsThere were two samples of pregnant women. Effectiveness was assessed using data from three French birth defect registries. Resource use for ultrasound screening was based on the French national healthcare database.Main outcome measuresThe main outcome measures were prenatal diagnosis (effectiveness) and the average number of ultrasounds (resource use). Statistical analyses included linear and logistic regression models to assess trends in resource use and effectiveness of prenatal testing, respectively.ResultsThe average number of ultrasound examinations per pregnancy significantly increased over the study period, from 2.47 in 2006 to 2.98 in 2014 (p=0.005). However, there was no significant increase in the odds of prenatal diagnosis. The probability of prenatal diagnosis was substantially higher for cases associated with a chromosomal anomaly (91.2%) than those without (51.8%). However, there was no evidence of an increase in prenatal detection of either over time.ConclusionsThe average number of ultrasound examinations per pregnancy increased over time, whereas the probability of prenatal diagnosis of congenital anomalies did not. Hence, there is a need to implement policies such as high-quality training programmes which can improve the efficiency of ultrasound examinations for prenatal detection of congenital anomalies.

Exposure to metals and congenital anomalies: a biomonitoring pilot study in pregnant women in Southern Israel

2013 ◽  
Vol 2013 (1) ◽  
pp. 3826
Author(s):  
Isabella Karakis ◽  
Daniella Landau ◽  
Maayan Yitshak-Sade ◽  
Doron Dukler ◽  
Reli Hershkovitz ◽  
...  
Keyword(s):  
Pilot Study ◽  
Pregnant Women ◽  
Congenital Anomalies

scholarly journals Risk factors for congenital anomalies in high risk pregnant women: A large study from South India

2017 ◽  
Vol 18 (1) ◽  
pp. 79-85 ◽  
Author(s):  
Tella Sunitha ◽  
Kattekola Rebekah Prasoona ◽  
Tiruvatturu Muni Kumari ◽  
Buragadda Srinadh ◽  
Madireddy Laxmi Naga Deepika ◽  
...  
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Pregnant Women ◽  
Congenital Anomalies ◽  
Large Study ◽  
South India

scholarly journals Level of folic acid awareness for the prevention of neural tube defects and associated factors among pregnant women in Adama, South East Ethiopia

2019 ◽  
Author(s):  
MESELECH AMBAW DESSIE ◽  
Ayanaw Worku Berihun
Keyword(s):  
Folic Acid ◽  
Pregnant Women ◽  
Neural Tube ◽  
Neural Tube Defects ◽  
Congenital Anomalies ◽  
Associated Factors ◽  
Healthcare Providers ◽  
P Value ◽  
Antenatal Visit ◽  
Cross Sectional

Abstract Abstract Background: Neural tube defects are congenital anomalies of the brain, spinal cord, and their surrounding structures. Folic acid intake before and during the early weeks of pregnancy could reduce neural tube and other birth defects. Folic acid usage in the protective period of pregnancy against the neural tube defects is related to high level of awareness. This study aimed at evaluating the level of folic acid awareness for the prevention of neural tube defects and associated factors among pregnant women in Adama, South East Ethiopia. Method: A descriptive cross-sectional study design was used. 398 consented pregnant women attending antenatal care in Adama were the participants of the study. The women were selected by using a systematic random sampling method. A structured pre-tested interviewer-administered questionnaire was used to collect the data. The questionnaire was concerned with participants’ demographic information, and their awareness about folic acid, roles of folic acid, and the recommended time of intake. Data were analyzed using SPSS version 20 statical software. Simple and multiple binary logistic regression analyses were conducted. 95% confidence interval and p-value were used to evaluate the association between dependent and independent variables. Results: Of the interviewed women, 20.9% reported having heard or read something about folic acid supplements. But only 1.01% and 6.03% were aware of the recommended time of intake and the role of folic acid in preventing neural tube defects and other congenital anomalies respectively. The healthcare providers were the primary source of information about folic acid, which account 78.3%. Folic acid awareness was associated with age, educational status, household monthly income, week of pregnancy at the first antenatal visit, any complication during current pregnancy, and use of folic acid during current pregnancy. Conclusions: Most of the pregnant women were not aware of folic acid, its importance and the recommended time of intake for preventing neural tube defects. Further effort is required from policymakers, healthcare providers, the media, and community to increase women's awareness about folic acid. Keywords: Folic acid, Awareness, Neural tube defects

scholarly journals Congenital anomalies of the central nervous system: prevalence in a fetal medicine service in the Brazilian Midwest

2021 ◽  
Author(s):  
Carolina Leão de Moraes ◽  
Fernanda Sardinha de Abreu Tacon ◽  
Andréa de Faria Rezende Matos ◽  
Natália Cruz e Melo ◽  
Michelle Hermínia Mesquita de Castro ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Prenatal Care ◽  
Pregnant Women ◽  
Congenital Anomalies ◽  
Fetal Medicine ◽  
Medicine Service ◽  
The Central Nervous System ◽  
Prospective Longitudinal ◽  
Cns Anomalies

Introduction: Approximately 21% of congenital anomalies (CA) involve the Central Nervous System (CNS), constituting one of the most common birth defects, affecting 1 to 10: 1,000 of live births. Objective: To analyze the prevalence of CNS anomalies diagnosed by obstetric ultrasound. Methods: Prospective longitudinal cohort study carried out in a public fetal medicine service in Goiânia with pregnant women who were attended in high-risk prenatal care. The patients were followed up during the ultrasound exams from March 2018 to March 2019. Results: 225 cases of pregnant women with ultrasound diagnoses of CA were surveyed during the investigated period. CNS anomalies were the most prevalent, being present in 34.22% (77/225) of the cases. The mean maternal age of pregnant women was 25.55 years and mean gestational age was 28.84 weeks. Hydrocephalus was identified in 23 pregnant women (29.87%), being the most prevalent CNS anomalie. Anencephaly was present in 24.68% (19/77) and holoprosencephaly in 18.18% (14/77). Other CA were also diagnosed (21/77), such as meningocele, spina bifida, acrania, among others. However, they showed a lower prevalence in relation to hydrocephalus, anencephaly and holoprosencephaly. Conclusion: The findings are essential for the planning and allocation of hospital resources and investment in health. Besides that, to adequate and specific prenatal care, is indispensable in the search for reducing the incidence of these malformations, morbidity and improving survival rates of the affected population.

scholarly journals Clinical Study to Evaluate Prevalence of Congenital Anomalies in Polyhydramnios

2021 ◽  
Vol 69 (1) ◽  
Author(s):  
Dr. Girdhar Gopal Nagar ◽  
Dr. Sanjana Jourwal ◽  
Dr. Nishu Goyal
Keyword(s):  
Congenital Anomaly ◽  
Amniotic Fluid ◽  
Pregnant Women ◽  
Gestational Age ◽  
Congenital Anomalies ◽  
Amniotic Fluid Index ◽  
Medical College ◽  
Obstetrics And Gynaecology ◽  
Increased Risk ◽  
Excessive Accumulation

Polyhydramnios is defined as excessive accumulation of amniotic fluid in relation to gestational age usually more than 2000 ml. More recently when Amniotic Fluid Index is more than 95th and 97th percentile for the gestational age condition is called as polyhydramnios. It is frequently associated with congenital anomalies of the fetus. The aim of our study was to observe prevalence of congenital anomalies in polyhydramnios. The present study was carried out in the department of Obstetrics and Gynaecology Umaid Hospital attached to Dr. S. N. Medical College, Jodhpur. In this study patients of polyhydramnios with gestational age between 20 to 42 weeks with amniotic fluid index more than 24 were enrolled after taking informed written consent. Degree of polyhydramnios was graded as mild, moderate and severe. Detail study of fetus was done for possible congenital anomalies. Congenital anomalies were confirmed with post-natal findings. There were 196 pregnant women with amniotic fluid index (AFI) > 24 cm. Prevalence of polyhydramnios was 1.66%. Congenital anomalies were present in 16.84% out of total 196 cases of polyhydroamnios. In pregnant women with severe polyhydramnios 51.51 % and in moderate 45.45% had congenital anomalies. Most common congenital anomaly was anencephaly (3.57%) followed by Hydrops (3.57%), Central nervous system, gastrointestinal and skeletal anomalies. Polyhydramnios is associated with increased risk of congenital anomalies hence Intrauterine condition of fetus should be monitored by using various diagnostic facilities like USG, Doppler, Echo-cardiography, amniocentesis and cordocentesis for possible congenital anomalies.

scholarly journals Incidence of congenital anomalies in newborns born to mothers with heart disease

2021 ◽  
Vol 8 (2) ◽  
pp. 346
Author(s):  
Kalpana R. Y. ◽  
Patil S. J.
Keyword(s):  
Heart Disease ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Congenital Anomalies ◽  
Heart Diseases ◽  
Small Sample Size ◽  
Small Sample ◽  
Medical Disorders ◽  
Study Population

Background: Heart disease is seen in 1% pregnancies. Prior studies have either looked at only the prevalence of congenital heart diseases (CHD) in newborns or the congenital anomalies (CA) in babies born to those with chronic medical disorders as a whole. There is only sparse literature looking specifically at their prevalence in mothers with heart disease.Methods: We aimed to study incidence of CAs in newborns born to mothers with heart disease and to study other relevant outcomes like prematurity, low birth weight and intrauterine growth retardation which have significant associations with CAs. The present study was a descriptive study consisting of retrospective and prospective data and consisted of pregnant women with heart disease from 2006 to 2010 and their newborns.Results: 55 pregnant women with their 55 newborns were selected. Among the 55 newborns, 15% babies had congenital anomalies including CHD, 13% had only CHDs. 21% babies with CHDs were born to CHD mothers and none of the mother baby diagnosis was completely concordant. No statistically significant outcome of CA in newborns born to mothers with heart disease was found. No statistically significant associations among low birth weight, prematurity and CAs was found.Conclusions: 15% had congenital anomalies including CHD. No statistically significant outcome of CA in newborns born to mothers with heart disease was found. Since the study population comprised of a small sample size, significant derivations could not be made. Further studies are required in this direction to see if associations are significant.

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