Evaluation of the evidence level for the use of radiofrequency in aesthetic treatments: A systematic review and meta‐analysis

2021 ◽  
Author(s):  
André Oliveira Paggiaro ◽  
Rafael Pinheiro ◽  
Kaolanna Soares ◽  
Viviane Fernandes Carvalho ◽  
Rolf Gemperli
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Evidence Level

scholarly journals Biomarkers for Diagnosis and Post-Kasai Portoenterostomy Prognosis of Biliary Atresia: Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Lin He ◽  
Dennis Kai Ming Ip ◽  
Greta Tam ◽  
Vincent Chi Hang Lui ◽  
Paul Kwong Hang Tam ◽  
...  
Keyword(s):  
Systematic Review ◽  
Liver Fibrosis ◽  
Biliary Atresia ◽  
Sensitivity And Specificity ◽  
Meta Analysis ◽  
Good Evidence ◽  
Kasai Portoenterostomy ◽  
Evidence Level ◽  
Sensitivity Specificity ◽  
Significant Liver Fibrosis

Abstract Objectives To evaluate the accuracy of biomarkers for the early diagnosis of biliary atresia (BA) and prognostic stratification after Kasai portoenterostomy (KPE). Methods We conducted a systematic review of PubMed, Web of Science, Embase, Scopus and OVID for English literatures reporting BA biomarkers published before August, 2020. Biomarkers selected for study was based on a good evidence-level (better than Grade B, level 2b). Screening, data extraction, and quality assessment were done in duplicate. Results A total of 51 eligible studies were involved for systematic review, and data from 12 of them (4182 subjects) were extracted for meta-analysis in the following 2 domains: (1) serum matrix metallopeptidase-7 (MMP-7), interleukin33 (IL-33) and γ-glutamyl transferase (GGT) to differentiate BA from non-BA; and (2) aspartate aminotransferase to platelet ratio index (APRi) to predict post-KPE liver fibrosis/cirrhosis. Summary sensitivity, specificity and the area under the curve (AUC) of MMP-7 for diagnosing BA were 96%, 91% and 0.9847, respectively. Summary sensitivity and specificity of IL-33 for diagnosing BA were 77% and 85%, respectively. Summary sensitivity, specificity and AUC of GGT for diagnosing BA were 80%, 79% and 0.9645, respectively. Summary sensitivity and specificity of APRi for predicting post-KPE liver fibrosis were 61% and 80%, respectively. Summary sensitivity, specificity and AUC of APRi for predicting post-KPE cirrhosis were 78%, 83% and 0.8729, respectively. Moreover, good evidence-level was shown in the investigations of serum IL-18 and IL-33 in distinguishing BA from healthy control, serum IL-18 for prognosing post-KPE persistent jaundice, and serum hyaluronic acid and MMP-7 for prognosing post-KPE significant liver fibrosis. Conclusions MMP-7, IL-33 and GGT are useful biomarker to assist the diagnosis of BA. APRi could be used to predict post-KPE significant liver fibrosis and cirrhosis. These non-invasive biomarkers could be integrated into the management protocol of BA.

scholarly journals Effectiveness of isometric exercise in the management of tendinopathy: a systematic review and meta-analysis of randomised trials

2020 ◽  
Vol 6 (1) ◽  
pp. e000760
Author(s):  
Christopher Clifford ◽  
Dimitris Challoumas ◽  
Lorna Paul ◽  
Grant Syme ◽  
Neal L Millar
Keyword(s):  
Systematic Review ◽  
Rotator Cuff ◽  
Meta Analysis ◽  
Isometric Exercise ◽  
Limited Evidence ◽  
Short Term ◽  
Level Of Evidence ◽  
Isotonic Exercise ◽  
Evidence Level ◽  
Level 3

ObjectiveTo systematically review and critically appraise the literature on the effectiveness of isometric exercise in comparison with other treatment strategies or no treatment in tendinopathy.DesignA systematic review and meta-analysis of randomised controlled trials.Data sourcesElectronic searches of Medline, Cumulative Index to Nursing and Allied Health Literature, EMBASE and Cochrane were undertaken from inception to May 2020.MethodsOverall quality of each study was determined based on a combined assessment of internal validity, external validity and precision. For each outcome measure, level of evidence was rated based on the system by van Tulder et al.ResultsTen studies were identified and included in the review, including participants with patellar (n=4), rotator cuff (n=2), lateral elbow (n=2), Achilles (n=1) and gluteal (n=1) tendinopathies. Three were of good and seven were of poor overall quality. Based on limited evidence (level 3), isometric exercise was not superior to isotonic exercise for chronic tendinopathy either immediately following treatment or in the short term (≤12 weeks) for any of the investigated outcome measures. Additionally, for acute rotator cuff tendinopathy, isometric exercise appears to be no more effective than ice therapy in the short term (limited evidence; level 3).SummaryIsometric exercise does not appear to be superior to isotonic exercise in the management of chronic tendinopathy. The response to isometric exercise is variable both within and across tendinopathy populations. Isometric exercise can be used as part of a progressive loading programme as it may be beneficial for selected individuals.PROSPERO registration numberCRD42019147179.

The effects of low-ratio n-6/n-3 PUFA on biomarkers of inflammation: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Yali Wei ◽  
Yan Meng ◽  
Na Li ◽  
Qian Wang ◽  
Liyong Chen
Keyword(s):  
Systematic Review ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Meta Analysis ◽  
Chain Polyunsaturated Fatty Acid ◽  
Inflammation Markers ◽  
Pufa Supplementation ◽  
Long Chain

The purpose of the systematic review and meta-analysis was to determine if low-ratio n-6/n-3 long-chain polyunsaturated fatty acid (PUFA) supplementation affects serum inflammation markers based on current studies.

The association between dietary inflammatory index and risk of central obesity in adults: An updated systematic review and meta-analysis

2020 ◽  
Vol 90 (5-6) ◽  
pp. 535-552 ◽  
Author(s):  
Mahdieh Abbasalizad Farhangi ◽  
Mahdi Vajdi
Keyword(s):  
Systematic Review ◽  
Observational Studies ◽  
Central Obesity ◽  
Assessment Tool ◽  
Weighted Mean Difference ◽  
Meta Analysis ◽  
Dietary Factors ◽  
Cross Sectional ◽  
Inflammatory Status ◽  
Obesity Indices

Abstract. Backgrounds: Central obesity, as a pivotal component of metabolic syndrome is associated with numerous co-morbidities. Dietary factors influence central obesity by increased inflammatory status. However, recent studies didn’t evaluate the association between central obesity and dietary inflammation index (DII®) that give score to dietary factors according to their inflammatory potential. In the current systematic review and meta-analysis, we summarized the studies that investigated the association between DII® with central obesity indices in the general populations. Methods: In a systematic search from PubMed, SCOPUS, Web of Sciences and Cochrane electronic databases, we collected relevant studies written in English and published until 30 October 2019. The population of included studies were apparently healthy subjects or individuals with obesity or obesity-related diseases. Observational studies that evaluated the association between DII® and indices of central obesity including WC or WHR were included. Results: Totally thirty-two studies were included; thirty studies were cross-sectional and two were cohort studies with 103071 participants. Meta-analysis of observational studies showed that higher DII® scores were associated with 1.81 cm increase in WC (Pooled weighted mean difference (WMD) = 1.813; CI: 0.785–2.841; p = 0.001). Also, a non-significant increase in the odds of having higher WC (OR = 1.162; CI: 0.95–1.43; p = 0.154) in the highest DII category was also observed. In subgroup analysis, the continent, dietary assessment tool and gender were the heterogeneity sources. Conclusion: The findings proposed that adherence to diets with high DII® scores was associated with increased WC. Further studies with interventional designs are necessary to elucidate the causality inference between DII® and central obesity indices.

Fear of pain and pain intensity: Meta-analysis and systematic review.

2020 ◽  
Vol 146 (5) ◽  
pp. 411-450 ◽  
Author(s):  
Tobias Markfelder ◽  
Paul Pauli
Keyword(s):  
Systematic Review ◽  
Pain Intensity ◽  
Meta Analysis ◽  
Fear Of Pain
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