scholarly journals Form and function in regenerative medicine: introduction

2015 ◽  
Vol 227 (6) ◽  
pp. 705-706 ◽  
Author(s):  
Fergal J. O'Brien ◽  
Garry P. Duffy
Keyword(s):  
Regenerative Medicine ◽  
Form And Function ◽  
And Function

scholarly journals From Hydra Regeneration to Human Brain Structural Plasticity: A Long Trip through Narrowing Roads

2011 ◽  
Vol 11 ◽  
pp. 1270-1299 ◽  
Author(s):  
Luca Bonfanti
Keyword(s):  
Stem Cells ◽  
Regenerative Medicine ◽  
Animal Species ◽  
Mammalian Brain ◽  
Regenerative Processes ◽  
Basic Principles ◽  
Form And Function ◽  
Heavy Burden ◽  
And Function ◽  
Human Nervous System

Regeneration is a strategy to maintain form and function throughout life. Studies carried out on animal models throughout the phylogenetic tree have flourished in the last decades in search of mechanisms underlying the regenerative processes. The development of such studies is strictly linked with stem cell research and both are viewed as one of the most promising outcomes for regenerative medicine; yet, regeneration, stem cells, and tissue repair do not seem to follow a logical path through the different animal species and tissues. As a result, some mammalian organs, e.g., kidney and brain, have lost most of their regenerative capacity. The human nervous system, although harboring neural stem cells, is placed at the extreme of “perennial” tissues. In addition, it is affected by neurodegenerative diseases, whose heavy burden is heightened by enhanced life spans. This review, starting from the basic principles of tissue regeneration viewed in a comparative context, tries to answer this question: To which extent can regenerative medicine be figured out in a mammalian brain equipped with many anatomical/evolutionary constraints?

Scanning tunneling microscopy (STM) of DNA and RNA

1989 ◽  
Vol 47 ◽  
pp. 34-35
Author(s):  
Patricia G. Arscott ◽  
Gil Lee ◽  
Victor A. Bloomfield ◽  
D. Fennell Evans
Keyword(s):  
Molecular Structures ◽  
Inorganic Materials ◽  
Resolving Power ◽  
Scanning Tunneling ◽  
Tunneling Microscopy ◽  
Form And Function ◽  
Dna And Rna ◽  
Calf Thymus ◽  
And Function ◽  
The Relationship

STM is one of the most promising techniques available for visualizing the fine details of biomolecular structure. It has been used to map the surface topography of inorganic materials in atomic dimensions, and thus has the resolving power not only to determine the conformation of small molecules but to distinguish site-specific features within a molecule. That level of detail is of critical importance in understanding the relationship between form and function in biological systems. The size, shape, and accessibility of molecular structures can be determined much more accurately by STM than by electron microscopy since no staining, shadowing or labeling with heavy metals is required, and there is no exposure to damaging radiation by electrons. Crystallography and most other physical techniques do not give information about individual molecules.We have obtained striking images of DNA and RNA, using calf thymus DNA and two synthetic polynucleotides, poly(dG-me5dC)·poly(dG-me5dC) and poly(rA)·poly(rU).

Re-examining the form and function of superstition

2011 ◽  
Author(s):  
Scott Fluke ◽  
Russell J. Webster ◽  
Donald A. Saucier
Keyword(s):  
Form And Function ◽  
And Function

A New Form and Function for Personality

2013 ◽  
Author(s):  
Joshua Wilt ◽  
William Revelle
Keyword(s):  
Form And Function ◽  
New Form ◽  
And Function

Ausnahmesegment

2018 ◽  
Vol 48 (191) ◽  
Author(s):  
Barbara Schönig
Keyword(s):  
Welfare State ◽  
Social Housing ◽  
Integrated Approach ◽  
New Paradigm ◽  
Development Models ◽  
Form And Function ◽  
Institutional Organization ◽  
National Welfare ◽  
And Function ◽  
The Welfare State

Going along with the end of the “golden age” of the welfare state, the fordist paradigm of social housing has been considerably transformed. From the 1980s onwards, a new paradigm of social housing has been shaped in Germany in terms of provision, institutional organization and design. This transformation can be interpreted as a result of the interplay between the transformation of national welfare state and housing policies, the implementation of entrepreneurial urban policies and a shift in architectural and urban development models. Using an integrated approach to understand form and function of social housing, the paper characterizes the new paradigm established and nevertheless interprets it within the continuity of the specific German welfare resp. housing regime, the “German social housing market economy”.

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