scholarly journals Addiction‐related neuroadaptations following chronic nicotine exposure

2021 ◽  
Author(s):  
Lauren Wills ◽  
Paul J. Kenny
Keyword(s):  
Nicotine Exposure ◽  
Chronic Nicotine

scholarly journals Systematic Review of Nicotine Exposure’s Effects on Neural Stem and Progenitor Cells

2021 ◽  
Vol 11 (2) ◽  
pp. 172
Author(s):  
Arrin C. Brooks ◽  
Brandon J. Henderson
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Inverse Correlation ◽  
Hippocampal Neurogenesis ◽  
Nicotine Exposure ◽  
Negative Consequences ◽  
Postnatal Neurogenesis ◽  
Cognitive Behaviors ◽  
Chronic Nicotine ◽  
Stem And Progenitor Cells

While various modalities of chronic nicotine use have been associated with numerous negative consequences to human health, one possible benefit of nicotine exposure has been uncovered. The discovery of an inverse correlation between smoking and Parkinson’s disease, and later Alzheimer’s disease as well, motivated investigation of nicotine as a neuroprotective agent. Some studies have demonstrated that nicotine elicits improvements in cognitive function. The hippocampus, along with the subventricular zone (SVZ), is a distinct brain region that allow for ongoing postnatal neurogenesis throughout adulthood and plays a major role in certain cognitive behaviors like learning and memory. Therefore, one hypothesis underlying nicotine-induced neuroprotection is possible effects on neural stem cells and neural precursor cells. On the other hand, nicotine withdrawal frequently leads to cognitive impairments, particularly in hippocampal-dependent behaviors, possibly suggesting an impairment of hippocampal neurogenesis with nicotine exposure. This review discusses the current body of evidence on nicotine’s effects on neural stem cells and neural progenitors. Changes in neural stem cell proliferation, survival, intracellular dynamics, and differentiation following acute and chronic nicotine exposure are examined.

scholarly journals Chronic Nicotine Exposure Abolishes Maternal Systemic and Renal Adaptations to Pregnancy in Rats

PLoS ONE ◽  
2016 ◽  
Vol 11 (2) ◽  
pp. e0150096 ◽  
Author(s):  
Vanessa Meira Ferreira ◽  
Clevia Santos Passos ◽  
Edgar Maquigussa ◽  
Roberto Braz Pontes ◽  
Cassia Toledo Bergamaschi ◽  
...  
Keyword(s):  
Nicotine Exposure ◽  
Chronic Nicotine

scholarly journals Sex differences in anxiety-like behavior and locomotor activity following chronic nicotine exposure in mice

2008 ◽  
Vol 439 (2) ◽  
pp. 187-191 ◽  
Author(s):  
Barbara J. Caldarone ◽  
Sarah L. King ◽  
Marina R. Picciotto
Keyword(s):  
Sex Differences ◽  
Locomotor Activity ◽  
Nicotine Exposure ◽  
Chronic Nicotine

scholarly journals B-PO04-010 THE EFFECT OF CHRONIC NICOTINE EXPOSURE ON CARDIAC ELECTROPHYSIOLOGY IN THE RABBIT HEART

Heart Rhythm ◽  
2021 ◽  
Vol 18 (8) ◽  
pp. S283-S284
Author(s):  
Amanda Guevara ◽  
Zhen Wang ◽  
Jessica L. Caldwell ◽  
Srinu Tapa ◽  
Lena Ngo ◽  
...  
Keyword(s):  
Cardiac Electrophysiology ◽  
Rabbit Heart ◽  
Nicotine Exposure ◽  
Chronic Nicotine

Chronic nicotine exposure in rat: A behavioural and biochemical study of tolerance

1981 ◽  
Vol 8 (1) ◽  
pp. 51-60 ◽  
Author(s):  
Ylva Falkeborn ◽  
Christer Larsson ◽  
Agneta Nordberg
Keyword(s):  
Biochemical Study ◽  
Nicotine Exposure ◽  
Chronic Nicotine

Chronic nicotine exposure enhances cutaneous axon reflexes in the rat

Neuroreport ◽  
1991 ◽  
Vol 2 (8) ◽  
pp. 421-424 ◽  
Author(s):  
Jennifer A. Grunfeld ◽  
Garry J. Tiedemann ◽  
Roderick A. Westerman
Keyword(s):  
Nicotine Exposure ◽  
Chronic Nicotine
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