(Unsuccessful) Binary Modeling of Successful Aging in the Oldest-Old Adults: A Call for Continuum-Based Measures

2014 ◽  
Vol 62 (8) ◽  
pp. 1597-1598 ◽  
Author(s):  
Theodore D. Cosco ◽  
Blossom C. M. Stephan ◽  
Carol Brayne
Keyword(s):  
Successful Aging ◽  
Oldest Old ◽  
Old Adults

scholarly journals Successful Aging and Subjective Well-Being Among Oldest-Old Adults

2014 ◽  
Vol 55 (1) ◽  
pp. 132-143 ◽  
Author(s):  
Jinmyoung Cho ◽  
Peter Martin ◽  
Leonard W. Poon ◽  
Keyword(s):  
Successful Aging ◽  
Oldest Old ◽  
Well Being ◽  
Subjective Well Being ◽  
Old Adults

scholarly journals Social Factors and Healthy Aging: Findings from the Louisiana Healthy Aging Study (LHAS)

2016 ◽  
Vol 5 (1) ◽  
pp. 50-56 ◽  
Author(s):  
Katie E. Cherry ◽  
Jennifer Silva Brown ◽  
Sangkyu Kim ◽  
S. Michal Jazwinski
Keyword(s):  
Successful Aging ◽  
Healthy Aging ◽  
Oldest Old ◽  
Age Groups ◽  
Later Life ◽  
Sociodemographic Factors ◽  
Physical Activities ◽  
Old Adults ◽  
Objective Health ◽  
Aging Study

Social behaviors are associated with health outcomes in later life. The authors examined relationships among social and physical activities and health in a lifespan sample of adults (N = 771) drawn from the Louisiana Healthy Aging Study (LHAS). Four age groups were compared: younger (21–44 years), middle-aged (45–64 years), older (65–84 years), and oldest-old adults (85–101 years). Linear regression analyses indicated that physical activity, hours spent outside of the house, and social support were significantly associated with selfreported health, after controlling for sociodemographic factors. Number of clubs was significantly associated with objective health status, after controlling for sociodemographic factors. These data indicate that social and physical activities remain important determinants of self-perceived health into very late adulthood. Implications of these data for current views on successful aging are discussed.

scholarly journals The Older They Are, the Less Successful They Become? Findings from the Georgia Centenarian Study

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Jinmyoung Cho ◽  
Peter Martin ◽  
Leonard W. Poon
Keyword(s):  
Successful Aging ◽  
Alternative Model ◽  
Economic Status ◽  
Oldest Old ◽  
Subjective Health ◽  
Cognitive Capacity ◽  
Phase Iii ◽  
Old Adults ◽  
Aging Model ◽  
Three Components

This study examined whether oldest-old adults are successful agers. Three hundred and six octogenarians and centenarians of Phase III of the Georgia Centenarian Study participated in this study. A first model examined Rowe and Kahn’s successful aging model (Rowe and Khan (1997 and 1998)) including the probability of disease, physical or cognitive capacity, and engagement with life. All three components were applied to assess how many oldest-old adults satisfied all three criteria. The result showed about 15% of octogenarians (15.1%), and none of centenarians satisfied all three components of successful aging. Consequently, a second alternative model focused on psychosocial aspects including three different components: subjective health, perceived economic status, and happiness. Different from Rowe and Kahn’s successful aging model, a total of 62.3% of octogenarians and 47.5% of centenarians satisfied all three components of the alternative model of successful aging. The results suggest that additional criteria of successful aging should be considered thereby expanding the concepts and multidimensional aspects of successful aging among oldest-old adults.

scholarly journals SUCCESSFUL AGING IN OLDEST-OLD ADULTS: ROLE OF PHYSICAL AND SOCIAL FACTORS

2017 ◽  
Vol 1 (suppl_1) ◽  
pp. 1183-1183
Author(s):  
K.E. Stanko ◽  
K.E. Cherry ◽  
S. Kim ◽  
S. Jazwinski
Keyword(s):  
Social Factors ◽  
Successful Aging ◽  
Oldest Old ◽  
Old Adults

scholarly journals Attitudes towards oldest‐old adults (age ≥80 years): A survey and international comparison between Swedish and Austrian nursing students

2021 ◽  
Author(s):  
Birgit Heckemann ◽  
Gerhilde Schüttengruber ◽  
Axel Wolf ◽  
Franziska Großschädl ◽  
Christopher Holmberg
Keyword(s):  
Nursing Students ◽  
International Comparison ◽  
Oldest Old ◽  
Old Adults

scholarly journals The Gut Microbiome, Aging, and Longevity: A Systematic Review

Nutrients ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3759
Author(s):  
Varsha D. Badal ◽  
Eleonora D. Vaccariello ◽  
Emily R. Murray ◽  
Kasey E. Yu ◽  
Rob Knight ◽  
...  
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Gut Microbiota ◽  
Gut Microbiome ◽  
Oldest Old ◽  
Amino Acid Synthesis ◽  
Old Adults ◽  
Age Related ◽  
Functional Features ◽  
Functional Pathways

Aging is determined by complex interactions among genetic and environmental factors. Increasing evidence suggests that the gut microbiome lies at the core of many age-associated changes, including immune system dysregulation and susceptibility to diseases. The gut microbiota undergoes extensive changes across the lifespan, and age-related processes may influence the gut microbiota and its related metabolic alterations. The aim of this systematic review was to summarize the current literature on aging-associated alterations in diversity, composition, and functional features of the gut microbiota. We identified 27 empirical human studies of normal and successful aging suitable for inclusion. Alpha diversity of microbial taxa, functional pathways, and metabolites was higher in older adults, particularly among the oldest-old adults, compared to younger individuals. Beta diversity distances significantly differed across various developmental stages and were different even between oldest-old and younger-old adults. Differences in taxonomic composition and functional potential varied across studies, but Akkermansia was most consistently reported to be relatively more abundant with aging, whereas Faecalibacterium, Bacteroidaceae, and Lachnospiraceae were relatively reduced. Older adults have reduced pathways related to carbohydrate metabolism and amino acid synthesis; however, oldest-old adults exhibited functional differences that distinguished their microbiota from that of young-old adults, such as greater potential for short-chain fatty acid production and increased butyrate derivatives. Although a definitive interpretation is limited by the cross-sectional design of published reports, we integrated findings of microbial composition and downstream functional pathways and metabolites, offering possible explanations regarding age-related processes.

scholarly journals Genes related to maintenance of autophagy and successful aging

2018 ◽  
Vol 76 (12) ◽  
pp. 831-839
Author(s):  
Carolina Fioroto Chaves ◽  
Diego Robles Mazzotti ◽  
Maysa Seabra Cendoroglo ◽  
Luiz Roberto Ramos ◽  
Sergio Tufik ◽  
...  
Keyword(s):  
Cell Survival ◽  
Differentially Expressed Genes ◽  
Expression Profile ◽  
Peripheral Blood ◽  
Successful Aging ◽  
Oldest Old ◽  
Enrichment Analysis ◽  
Differentially Expressed ◽  
Expression Of Genes ◽  
Transcriptional Process

ABSTRACT Considering aging as a phenomenon in which there is a decline in essential processes for cell survival, we investigated the autophagic and proteasome pathways in three different groups: young, older and oldest old male adults. The expression profile of autophagic pathway-related genes was carried out in peripheral blood, and the proteasome quantification was performed in plasma. No significant changes were found in plasma proteasome concentrations or in correlations between proteasome concentrations and ages. However, some autophagy- and/or apoptosis-related genes were differentially expressed. In addition, the network and enrichment analysis showed an interaction between four of the five differentially expressed genes and an association of these genes with the transcriptional process. Considering that the oldest old individuals maintained both the expression of genes linked to the autophagic machinery, and the proteasome levels, when compared with the older group, we concluded that these factors could be considered crucial for successful aging.

Sign in / Sign up

Export Citation Format

Share Document