Microencapsulation of Lactobacillus casei Shirota by spray drying using different combinations of wall materials and application for probiotic dairy dessert

2017 ◽  
Vol 41 (5) ◽  
pp. e13198 ◽  
Author(s):  
Osman Gul
Keyword(s):  
Spray Drying ◽  
Lactobacillus Casei ◽  
Lactobacillus Casei Shirota ◽  
Wall Materials

The probiotic Lactobacillus casei Shirota attenuates symptoms of vestibular migraine: a randomised placebo-controlled double-blind clinical trial

2020 ◽  
Vol 11 (5) ◽  
pp. 469-476
Author(s):  
X. Qi ◽  
G. Fan ◽  
H. Jia
Keyword(s):  
Depressive Symptoms ◽  
Lactobacillus Casei ◽  
Daily Basis ◽  
Vestibular Migraine ◽  
Double Blind ◽  
Beneficial Effects ◽  
Lactobacillus Casei Shirota ◽  
Probiotic Lactobacillus ◽  
Vestibular Symptoms

Vestibular migraine (VM) has emerged as one of the major vestibular syndromes. Although probiotics have exhibited beneficial effects on migraine headache, its effect on VM is not clear. This trial aimed to investigate the treatment efficacy of the probiotic Lactobacillus casei Shirota (LcS) on symptoms of VM. 247 VM patients were enrolled, of which 204 eligible patients receiving either LcS or placebo on a daily basis completed the 4 month study. They were re-visited at 2 and 4 months after study initiation to assess treatment outcomes. The primary endpoints were vestibular symptoms, evaluated by the number of vertiginous attacks during the past week, the Vertigo Severity Score (VSS), and Dizziness Handicap Inventory (DHI) scores. The secondary endpoints were anxiety and depressive symptoms, evaluated using Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) scores. Efficacy of LcS over placebo was not obvious at 2 month follow-up. At 4 month follow-up, while both LcS and placebo groups of VM patients displayed alleviated symptoms, the extents of the improvements were significantly better in LcS group than those of placebo group, with regard to vestibular symptoms using DHI and VSS, as well as anxiety and depressive symptoms using BAI and BDI. Although placebo effect cannot be ignored in intervention for VM patients, the probiotic LcS still exhibits considerable efficacy against VM symptoms over a 4 month study period, supporting further clinical study of a larger and more diverse cohort.

scholarly journals Oral administration of Lactobacillus casei Shirota can ameliorate the adverse effect of an acute aflatoxin exposure in Sprague Dawley rats

2018 ◽  
Vol 88 (3-4) ◽  
pp. 199-208
Author(s):  
Elham Nikbakht ◽  
Rosita Jamaluddin ◽  
S. Mohd Redzwan ◽  
Saman Khalesi
Keyword(s):  
Adverse Effect ◽  
Lactobacillus Casei ◽  
Health Effect ◽  
Acute Exposure ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Lactobacillus Casei Shirota ◽  
Probiotic Treatment ◽  
Significant Difference ◽  
Aflatoxin B

Abstract. Aflatoxin B1 (AFB1) is a toxic compound commonly found in some crops with an adverse health effect on human and animals. Some beneficial microorganisms (or probiotics) such as lactic acid bacteria have shown the ability to reduce the bioavailability of aflatoxins and its intestinal absorption. However, the dose and duration of aflatoxins exposure and probiotic treatment can influence the ability of probiotics to remove aflatoxins. Therefore, this research aimed to investigate the efficacy of oral probiotic Lactobacillus casei Shirota strain (LcS) induction in an acute exposure to AFB1 in rats. Experimentally, Sprague Dawley rats were divided into three groups: AFB1 only (n = 9); AFB1 treated with LcS (n = 9); and control (no AFB1 exposure) (n = 6) groups. The blood AFB1 level of rats treated with LcS was slightly lower than the untreated AFB1 induced rats (11.12 ± 0.71 vs 10.93 ± 0.69 ng g–1). Also, LcS treatment slightly moderated the liver and kidney biomarkers in AFB1 induced rats. However, a trend for a significant difference was only observed in ALT of AFB1 induced rats treated with LcS compared to their counterparts (126.11 ± 36.90 vs 157.36 ± 15.46, p = 0.06). Rats’ body weight decreased in all animals force-fed with AFB1 with no significant difference between LcS treatment compared to the counterpart. In conclusion, this experiment indicated that probiotic LsC was able to slightly ameliorate the adverse effect of an acute exposure to AFB1 in rats. However, future studies with longer probiotics treatment or higher probiotics dose is required to confirm these findings.

scholarly journals Impact of Wall Materials on Physicochemical Properties of Microencapsulated Fish Oil by Spray Drying

2014 ◽  
Vol 7 (8) ◽  
pp. 2354-2365 ◽  
Author(s):  
Parastoo Pourashouri ◽  
Bahare Shabanpour ◽  
Seid Hadi Razavi ◽  
Seid Mahdi Jafari ◽  
Ali Shabani ◽  
...  
Keyword(s):  
Physicochemical Properties ◽  
Fish Oil ◽  
Spray Drying ◽  
Wall Materials ◽  
Microencapsulated Fish Oil

The effect of probiotic treatment on elderly patients with distal radius fracture: a prospective double-blind, placebo-controlled randomised clinical trial

2016 ◽  
Vol 7 (5) ◽  
pp. 631-637 ◽  
Author(s):  
M. Lei ◽  
L-M. Hua ◽  
D-W. Wang
Keyword(s):  
Clinical Trial ◽  
Elderly Patients ◽  
Distal Radius Fracture ◽  
Distal Radius ◽  
Lactobacillus Casei ◽  
Radius Fracture ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Lactobacillus Casei Shirota ◽  
Probiotic Treatment

Probiotic treatment has been shown to improve bone formation, increase bone mass density and prevent bone loss. We aimed to assess the effect of probiotic treatment on functional recovery in elderly patients with a distal radius fracture. A total of 417 elderly patients with an acute distal radius fracture were enrolled in this double-blind placebo-controlled clinical trial. They were randomised to receive skimmed milk containing either a commercial probiotic (Lactobacillus casei Shirota) or placebo daily for a period of 6 months after the fracture. Treatment outcomes were the DASH (disabilities of the arm, shoulder and hand) score, pain, complex regional pain syndrome (CRPS) score, active range of motion and grip strength, all of which were measured on a monthly basis. Throughout the duration of the study, DASH score, pain, CRPS score, wrist flexion and grip strength of patients receiving probiotics exhibited a significantly faster pace of improvement than those on placebo, with treatment outcomes of patients receiving Lactobacillus casei Shirota at month 4 at comparable levels with those of patients receiving placebo at month 6. In elderly patients with a fracture of the distal radius, administration of the probiotic could greatly accelerating the healing process.

ÁCIDOS LÁTICO E ACÉTICO OBTIDOS A PARTIR DA FERMENTAÇÃO DO LEITE COM Euterpe oleracea Mart. (AÇAÍ) POR Lactobacillus casei Shirota

2020 ◽  
pp. 36-43
Author(s):  
Adriele Torquato Rodrigues ◽  
Adriellen Oliveira Branco ◽  
Rithely de Aquino dos Santos ◽  
Victória Cristiane Moura Coelho ◽  
Edailson de Alcântara Corrêa
Keyword(s):  
Lactobacillus Casei ◽  
Euterpe Oleracea ◽  
Lactobacillus Casei Shirota ◽  
Euterpe Oleracea Mart
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