Antioxidant and hepatoprotective potential of Plantago major growing in Egypt and its major phenylethanoid glycoside, acteoside

2018 ◽  
Vol 42 (5) ◽  
pp. e12567 ◽  
Author(s):  
Ahmed H. Eldesoky ◽  
Rehab F. Abdel-Rahman ◽  
Osama K. Ahmed ◽  
Gamal A. Soliman ◽  
Abdulaziz S. Saeedan ◽  
...  
Keyword(s):  
Plantago Major ◽  
Phenylethanoid Glycoside

Антиаритмическое действие флавоноидной фракции экстракта Plantago major L.

2019 ◽  
Vol 52 (12) ◽  
pp. 30-33
Author(s):  
Шункор Садуллаевич Хушматов ◽  
Рустам Расулджанович Махмудов
Keyword(s):  
Plantago Major

Изучено антиаритмическое действие флавоноидной фракции экстракта Plantago major L. (0,05 мг/мл). Установлено, что исследованные фракции подавляют частоту сокращений папиллярной мышцы сердца крысы на фоне аритмии, вызванной аконитином (1 мкМ) в условиях in vitro. Анализируя литературные и полученные данные, можно предположить, что антиаритмический эффект изученных флавоноидных фракций может быть связан с модуляцией функциональной активности Na+- и Са2+-каналов в кардиомиоцитах.

Efficacy of Aloe vera/ Plantago Major Gel in Diabetic Foot Ulcer: A Randomized Double-Blind Clinical Trial

2019 ◽  
Vol 16 (2) ◽  
pp. 223-231 ◽  
Author(s):  
Younes Najafian ◽  
Zahra M. Khorasani ◽  
Mona N. Najafi ◽  
Shokouh S. Hamedi ◽  
Marjan Mahjour ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Diabetic Foot ◽  
Intervention Group ◽  
Aloe Vera ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Control Group ◽  
Plantago Major ◽  
Double Blind ◽  
Significant Difference

Background:Diabetic foot ulcer (DFU) is one of the most common complications of diabetic patients. Mostly, non-healing DFU leads to infection, gangrene, amputation and even death. High costs and poor healing of the wounds need a new treatment such as alternative medicine. So, the aim of this study was to evaluate the efficacy of Aloe vera/ Plantago major gel (Plantavera gel) in healing of DFUMethods:Forty patients with DFU enrolled in a double-blind randomized clinical trial. The patients who were randomly assigned into the intervention group (n = 20), received topical Plantavera gel in addition to the routine cares, whereas the patients in the control group (n = 20), received topical Placebo gel in addition to the routine cares. Intervention was done twice a day for 4 weeks in the both groups. Photography and an evaluation of DFU healing were conducted by a checklist and then were scored at baseline and at the end of each week. The collected data was analyzed by SPSS software.Results:At the end of the study, there was a significant difference between the two groups in terms of total ulcer score (P<0.001) and Plantavera gel significantly reduced the ulcer surface comparing with the control group (P=0.039). However, there was not a significant difference between the two groups (P=0.263) in terms of the ulcer depth. During this study, no side effect was observed for Plantavera gel in the intervention group.Conclusion:Topical Plantavera gel seems to be an effective, cheap and safe treatment. Of course, further studies are required to confirm the properties of the wound healing of this gel.

Ảnh hưởng của điều kiện ánh sáng và thời gian sinh trưởng lên hàm lượng một số hợp chất trong cây mã đề (Plantago major)

2019 ◽  
Vol 55(5) ◽  
pp. 66
Author(s):  
Nguyễn Văn Ây ◽  
Trần Thanh Mến ◽  
Đỗ Tấn Khang ◽  
Nguyễn Thị Quới Trâm
Keyword(s):  
Plantago Major

scholarly journals Protective Antifungal Activity of Plantago major Extract Against the Phytopathogenic Fungi Phytophthora cinnamomi, Diplodia corticola and Colletotrichum Species

Proceedings ◽  
2020 ◽  
Vol 70 (1) ◽  
pp. 94
Author(s):  
Cláudia Ferreira ◽  
Rui Oliveira
Keyword(s):  
Antifungal Activity ◽  
Secondary Metabolites ◽  
Plant Extracts ◽  
Phytophthora Cinnamomi ◽  
Fungal Infections ◽  
Petri Dish ◽  
Phytopathogenic Fungi ◽  
Colletotrichum Acutatum ◽  
Lower Probability ◽  
Plantago Major

Synthetic fungicides for crops protection raise environmental and human concerns due to accumulation in edible vegetables, showing significant toxicity to humans, and in soil, groundwater and rivers, affecting ecological balance. In addition, they are prone to the development of resistant strains because of the single target-based mechanism of action. Plant extracts provide attractive alternatives, as they constitute a rich source of biodegradable secondary metabolites, such as phenols, flavonoids and saponins, which have multiple modes of antifungal action and a lower probability of the development of resistant fungi. This work has the objective of identifying plant extracts with antifungal activity, aiming to contribute to food safety and sustainable agricultural practices. We selected a saponin-containing plant, Plantago major, and extracted secondary metabolites with 50% (v/v) ethanol, dried by evaporation, and dissolved in water. For antifungal activity, the phytopathogenic fungi Colletotrichum acutatum, Colletotrichum gloeosporioides, Colletotrichum godetiae, Colletotrichum nymphaeae, Diplodia corticola and Phytophthora cinnamomi were selected because they affect fruits and vegetables, such as strawberry, almond, apple, avocado, blueberry and chestnut trees. The aqueous extract was incorporated into PDA medium at different concentrations and mycelial discs were placed in the center of each Petri dish. Growth was measured as the radial mycelial growth at 3, 6, and 9 days incubation at 25 °C in the dark. The maximum growth inhibition (32.2%) was obtained against P. cinnamomi with 2000 µg/mL extract followed by C. gloeosporioides (25.7%) on the sixth day and by C. godetiae and C. nymphaeae (21.1%) on the ninth day. Results show that P. major presents antifungal activity in all phytopathogenic fungi tested and the extract can be used to protect important crops, by inhibiting the development of fungal infections and promoting food security and a sustainable agriculture.

The response of the accumulator plants Noccaea caerulescens, Noccaea goesingense and Plantago major towards the uranium

2021 ◽  
Vol 229-230 ◽  
pp. 106544
Author(s):  
Anna Burger ◽  
Marieluise Weidinger ◽  
Nils Baumann ◽  
Andreas Vesely ◽  
Irene Lichtscheidl
Keyword(s):  
Plantago Major ◽  
Noccaea Caerulescens
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