scholarly journals Addressing challenges associated with long‐term topical treatment and benefits of proactive management in patients with psoriasis

2021 ◽  
Vol 35 (S1) ◽  
pp. 35-41 ◽  
Author(s):  
M. Lebwohl ◽  
D. Thaçi ◽  
R.B. Warren
Keyword(s):  
Topical Treatment ◽  
Proactive Management

Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin

2008 ◽  
Vol 17 (11) ◽  
pp. 946-952 ◽  
Author(s):  
Marek Haftek ◽  
Sophie Mac-Mary ◽  
Marie-Aude Le Bitoux ◽  
Pierre Creidi ◽  
Sophie Seité ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Human Skin ◽  
Topical Treatment ◽  
Long Term Effects ◽  
Structural Evaluation

scholarly journals Strategic stakeholder management: theoretical concept and features of application

2021 ◽  
Author(s):  
Zoia Halushka
Keyword(s):  
Strategic Management ◽  
Stakeholder Management ◽  
Theoretical Concept ◽  
Business Strategies ◽  
Modern Concept ◽  
Main Task ◽  
Theoretical Approaches ◽  
Proactive Management ◽  
Unstable Environment

The article examines the development of the theoretical concept of stakeholders, a comparative analysis of approaches to the definition and grouping of stakeholders depending on their impact on the functioning of the organisation. The objective nature of the emergence of strategic stakeholder management as a modern concept of organisation management, operating in an unstable environment, is substantiated. Based on the analysis of theoretical approaches to substantiation of the essence of the concept of stakeholder management, the necessity and peculiarities of its application in strategic management of organisations in modern business conditions are shown. The main task of stakeholder management is identified, which is not just to maintain mutually beneficial interaction between all stakeholders, but to find mechanisms to improve the effectiveness of joint activities as a holistic system that includes the interests of all stakeholders. Based on the generalisation of all tools and mechanisms of strategic stakeholder management, two main approaches are identified - resource and relationship. It is noted that the relational approach means the formation of social capital, which in itself is a strategic resource, as it ensures the reputation of the business and promotes competitive advantage. It was found that in strategic management there are already certain principles of stakeholder management: systematic relationships, strategic orientation of all stakeholders to develop business strategies that take into account the interests, values and long-term goals of the organisation; mutual benefit of relations with stakeholders; the need to balance the interests of stakeholders; proactive management; focus on sustainable development and long-term relationships; transparency and accountability in non-financial relationships. It is substantiated that the result of effective stakeholder management is the value of the organisation. It is created by the joint efforts of all stakeholders on the basis of their interaction and depends on the availability, sufficiency and effectiveness of management of all resources and types of capital.

Efficacy and tolerability of a 5% lidocaine medicated plaster for the topical treatment of post-herpetic neuralgia: results of a long-term study

2009 ◽  
Vol 25 (5) ◽  
pp. 1295-1305 ◽  
Author(s):  
Guy Hans ◽  
Rainer Sabatowski ◽  
Andreas Binder ◽  
Irmgard Boesl ◽  
Peter Rogers ◽  
...  
Keyword(s):  
Topical Treatment ◽  
Post Herpetic Neuralgia ◽  
Term Study ◽  
Long Term Study

scholarly journals Intracranial Atherosclerosis in Stroke Patients, Which Risk Factors Are Important? A Study From Mixed Ethnic Population in Singapore.

2021 ◽  
Author(s):  
shrikant Pande ◽  
May Thiri Lwin ◽  
Aye Aye Khine ◽  
May Win Myat ◽  
Lorecar Lolong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multivariable Analysis ◽  
Large Artery ◽  
Intracranial Atherosclerosis ◽  
Stroke Patients ◽  
Term Survival ◽  
Significant Stenosis ◽  
Proactive Management ◽  
History Of

Abstract Intracranial atherosclerosis (ICAD) although more common in Asians, has not been studied from Singapore population. The aim of this study is to identify prevalence ICAD in stroke subjects, its association with comorbidities, stroke subtypes and long-term survival. We performed retrospective analysis of 681 stroke patients, 327(48%) had ICAD) with 232 (71%) having one or more intracranial artery with significant stenosis. ICAD was associated with older age, ischaemic strokes, total anterior circulation syndrome (TACS), large artery strokes (p<0.001), peripheral vascular disease (PVD, p=0.018), diabetes mellitus (DM), and with history of hyperlipidemia. In addition, higher serum potassium (p=0.046) and glucose (p<0.001), lower haemoglobin (p=0.040) and aortic valve sclerosis were significantly associated with ICAD (p<0.001). Multivariable analysis showed a significant independent association of ICAD with advancing age, history of hyperlipidemia and DM.In ischemic strokes (489), 311(64%) had ICAD of which 229(72%) had significant stenosis. Of the 192 hemorrhagic strokes, 16 (8%) had ICAD.Conclusion: The prevalence of ICAD, especially in ischemic strokes, from our study is high. As modifiable risk factors such as hyperlipidemia and DM appear to be associated with ICAD, then proactive management of these conditions may improve long term associated complications. Prospective studies may help to validate our findings.

scholarly journals LONG-TERM CONTROL OF SKIN ALLERGIC INFLAMMATION IN ATOPIC DERMATITIS PATIENTS

2014 ◽  
Vol 11 (3) ◽  
pp. 30-36
Author(s):  
O G ELISYUTINA ◽  
E S FEDENKO
Keyword(s):  
Atopic Dermatitis ◽  
Topical Treatment ◽  
Allergic Inflammation ◽  
Calcineurin Inhibitors ◽  
Intermittent Treatment ◽  
Topical Corticosteroids ◽  
Topical Calcineurin Inhibitors ◽  
Proactive Therapy

Modern approaches to topical treatment of atopic dermatitis (ad) are presented in the review. the application of different proactive therapy patterns like topical corticosteroids intermittent treatment and topical calcineurin inhibitors as antirecurrent therapy of ad patients are discussed.

scholarly journals Clinical Course and Nutritional Management of Propionic and Methylmalonic Acidemias

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Amira Mobarak ◽  
Heba Dawoud ◽  
Hanaa Nofal ◽  
Amr Zoair
Keyword(s):  
Protein Intake ◽  
Clinical Course ◽  
Age Of Onset ◽  
Length Of Hospital Stay ◽  
Ammonia Level ◽  
Strong Negative Correlation ◽  
Natural Protein ◽  
Proactive Management ◽  
Increased Risk

Propionic and methylmalonic acidemias result in multiple health problems including increased risk for neurological and intellectual disabilities. Knowledge regarding factors that correlate to poor prognosis and long-term outcomes is still limited. In this study, we aim to provide insight concerning clinical course and long-term complications by identifying possible correlating factors to complications. Results. This is a retrospective review of 20 Egyptian patients diagnosed with PA (n = 10) and MMA (n = 10) in the years 2014–2018. PA patients had lower DQ/IQ and were more liable to hypotonia and developmental delay. The DQ/IQ had a strong negative correlation with length of hospital stay, frequency of PICU admissions, time delay until diagnosis, and the mode ammonia level. However, DQ/IQ did not correlate with age of onset of symptoms or the peak ammonia level at presentation. Both the growth percentiles and albumin levels had a positive correlation with natural protein intake and did not correlate with the total protein intake. Additionally, patients on higher amounts of medical formula did not necessarily show an improvement in the frequency of decompensation episodes. Conclusion. Our findings indicate that implementation of NBS, vigilant and proactive management of decompensation episodes, and pursuing normal ammonia levels during monitoring can help patients achieve a better neurological prognosis. Furthermore, patients can have a better outcome on mainly natural protein; medical formula should only be used in cases where patients do not meet 100–120% of their DRI from natural protein.

scholarly journals Topical Treatment of Psoriasis Vulgaris: The Swiss Treatment Pathway

Dermatology ◽  
2021 ◽  
pp. 1-13
Author(s):  
Julia-Tatjana Maul ◽  
Florian Anzengruber ◽  
Curdin Conrad ◽  
Antonio Cozzio ◽  
Peter Häusermann ◽  
...  
Keyword(s):  
Topical Treatment ◽  
Systemic Treatment ◽  
Severe Disease ◽  
Treatment Options ◽  
Maintenance Phase ◽  
Current Treatment ◽  
Induction Phase ◽  
Individual Choice ◽  
Proactive Management ◽  
The Individual

Topical treatment is crucial for the successful management of plaque psoriasis. Topicals are used either as a stand-alone therapy for mild psoriasis or else in combination with UV or systemic treatment for moderate-to-severe disease. For the choice of a suitable topical treatment, the formulation matters and not just the active substances. This expert opinion paper was developed via a non-structured consensus process by Swiss dermatologists in hospitals and private practices to illustrate the current treatment options to general practitioners and dermatologists in Switzerland. Defining treatment goals together with the patient is crucial and increases treatment adherence. Patients’ personal preferences and pre-existing experiences should be considered and their satisfaction with treatment and outcome regularly assessed. During the induction phase of “classical” mild-to-moderate psoriasis, the fixed combination of topical calcipotriol (Cal) 50 μg/g and betamethasone dipropionate (BD) 0.5 mg/g once daily is frequently used for 4–8 weeks. During the maintenance phase, a twice weekly (proactive) management has proved to reduce the risk of relapse. Of the fixed combinations, Cal/BD aerosol foam is the most effective formulation. However, the individual choice of formulation should be based on a patient’s preference and the location of the psoriatic plaques. Tailored recommendations are given for the topical management of specific areas (scalp, facial, intertriginous/genital, or palmoplantar lesions), certain symptoms (hyperkeratotic or hyperinflammatory forms) as well as during pregnancy or a period of breastfeeding. As concomitant basic therapy, several emollients are recommended. If topical treatment alone does not appear to be sufficient, the regimen should be escalated according to the Swiss S1-guideline for the systemic treatment of psoriasis.

Sign in / Sign up

Export Citation Format

Share Document