Effects of particulate matter on healthy human skin: a panel study using a smartphone application measuring daily skin condition

2019 ◽  
Vol 33 (7) ◽  
pp. 1363-1368 ◽  
Author(s):  
J.H. Park ◽  
S.J. Oh ◽  
J.H. Lee
2020 ◽  
Author(s):  
Se Jin Oh ◽  
Dokyoung Yoon ◽  
Ji-Hye Park ◽  
Jong Hee Lee

Abstract Background The influence of airborne particulate matter (PM) on skin has primarily been studied in patients with skin diseases such as atopic dermatitis. Recently, the effect of PM on healthy human skin has gained attention. This study aimed to evaluate the relationship between PM concentration and objective skin changes in healthy subjects. Methods This prospective study enrolled 25 healthy volunteers without any skin disease. Data regarding daily meteorological parameters and air pollution were collected during a high-PM period and a low-PM period for 14 days. Environmental and lifestyle factors that might influence skin conditions of subjects were also collected during the study period. Biophysical parameters of the skin such as transepidermal water loss (TEWL), hydration, erythema index, and melanin index were measured. Pores, wrinkles, sebum, and skin tone were evaluated using a facial analysis system. Results Mean TEWL value during the high-PM period was significantly higher than that during the low-PM period (10.16 g/m2/h vs. 5.99 g/m2/h, p = 0.0005). Mean erythema index was significantly higher in the high-PM period than that in the low-PM period (4.3 vs. 3.42, p = 0.038). For facial analysis system indices, uniformity of skin tone was higher in the low-PM period than that in the high-PM period (p < 0.0001). In addition, with increasing PM10 and PM2.5, TEWL also showed increase when other environmental components were constant [regression coefficient (RC) = 0.1529, p < 0.0001 for PM10; RC = 0.2055, p = 0.0153 for PM2.5]. Conclusions Increased PM concentrations may contribute to disturbed barrier function, increased facial erythema, and uneven skin tone even in healthy human skin.


Physiology ◽  
2001 ◽  
Vol 16 (1) ◽  
pp. 33-37 ◽  
Author(s):  
M. Schmelz ◽  
L. J. Petersen

The combination of vasodilation and protein extravasation following activation of nociceptors has been termed “neurogenic inflammation.” In contrast to rodents, no neurogenic protein extravasation can be elicited in healthy human skin. Dermal microdialysis has considerably increased our knowledge about neurogenic inflammation in human skin, including the involvement of mast cells.


2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Richard S. Ahn ◽  
Keyon Taravati ◽  
Kevin Lai ◽  
Kristina M. Lee ◽  
Joanne Nititham ◽  
...  

2020 ◽  
Vol 27 (6) ◽  
Author(s):  
Inga Saknite ◽  
Zijun Zhao ◽  
J. Randall Patrinely ◽  
Michael Byrne ◽  
Madan Jagasia ◽  
...  

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