Ablative fractional laser intensifies treatment outcome of scalp actinic keratoses with ingenol mebutate: a case report

2015 ◽  
Vol 30 (5) ◽  
pp. 854-855 ◽  
Author(s):  
K.E. Karmisholt ◽  
M. Haedersdal
Keyword(s):  
Treatment Outcome ◽  
Case Report ◽  
Ingenol Mebutate ◽  
Fractional Laser ◽  
Actinic Keratoses ◽  
Ablative Fractional Laser

scholarly journals Ablative fractional laser improves treatment of actinic keratoses with Ingenol Mebutate

2016 ◽  
Vol 14 (3) ◽  
pp. 200-205 ◽  
Author(s):  
Steven Nisticò ◽  
Mario Sannino ◽  
Ester Del Duca ◽  
Federica Tamburi ◽  
Ugo Bottoni ◽  
...  
Keyword(s):  
Open Study ◽  
Skin Diseases ◽  
Therapeutic Option ◽  
Ingenol Mebutate ◽  
Fractional Laser ◽  
Treatment Area ◽  
Actinic Keratoses ◽  
Ablative Fractional Laser ◽  
Efficacy Profile

Actinic keratoses (AK) are pre-neoplastic lesions related to an excessive ultraviolet exposure that represent an emerging issue in the area of skin diseases which undergo high risk for developing squamous cell carcinoma (SCC). In this open study, we tested the safety efficacy profile of sequential ablative laser and Ingenol Mebutate gel (IngMeb). Thirteen patients with a total of 99 lesions were selected for this open study. When multiple lesions on the same area were found, the treatment area was split in half. In one group, fractional CO2 laser microablative treatment was performed the day before three daily applications of IngMeb 150 lg/g; the other group received IngMeb without previous laser ablation. Fifty-six lesions were treated with laser and IngMeb and a total of 43 lesions in the second group were treated with IngMeb alone. Results at the 12-week follow-up visit showed that a clearance rate of 50/56 (89.2%) had been achieved. On the side that was not pre-treated with laser, 31 out of 43 lesions were cleared (72.1%). In our opinion, ablative fractional laser treatment could improve topical treatment of AKs, or provide a further therapeutic option for resistant patients.

scholarly journals Multidisciplinary treatment of a massive head and neck keloid scar: A case report

2020 ◽  
Vol 8 ◽  
pp. 2050313X2093603
Author(s):  
Maninder S Longowal ◽  
Barbara Humphreys RN ◽  
Todd K Remington
Keyword(s):  
Case Report ◽  
Topical Corticosteroid ◽  
Head And Neck ◽  
Multidisciplinary Treatment ◽  
Fractional Laser ◽  
Recurrence Rates ◽  
Keloid Scar ◽  
Patient Morbidity ◽  
Keloid Scars ◽  
Ablative Fractional Laser

Keloid scars can lead to significant patient morbidity and disfigurement, especially when located on the head and neck. Massive keloid scars are particularly difficult to manage due to ulceration, infection, pain, and high recurrence rates following excision. We report the successful treatment of a massive head and neck keloid scar with excision and grafting, post-excisional radiotherapy, and ablative fractional laser-assisted topical corticosteroid delivery.

Ablative fractional laser alters biodistribution of ingenol mebutate in the skin

2015 ◽  
Vol 307 (6) ◽  
pp. 515-522 ◽  
Author(s):  
A. M. Erlendsson ◽  
E. H. Taudorf ◽  
A. H. Eriksson ◽  
C. S. Haak ◽  
J. R. Zibert ◽  
...  
Keyword(s):  
Ingenol Mebutate ◽  
Fractional Laser ◽  
Ablative Fractional Laser

scholarly journals Ablative fractional laser‐assisted photodynamic therapy for lentigo maligna: a prospective pilot study

2019 ◽  
Vol 34 (3) ◽  
pp. 510-517
Author(s):  
J.E. Räsänen ◽  
N. Neittaanmäki ◽  
L. Jeskanen ◽  
I. Pölönen ◽  
E. Snellman ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Pilot Study ◽  
Fractional Laser ◽  
Lentigo Maligna ◽  
Prospective Pilot Study ◽  
Ablative Fractional Laser
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