Changes in nuclear morphology and chromatin texture of basal keratinocytes in melasma

2014 ◽  
Vol 29 (4) ◽  
pp. 809-812 ◽  
Author(s):  
G. Brianezi ◽  
A.C. Handel ◽  
J.V. Schmitt ◽  
L.D.B. Miot ◽  
H.A. Miot
Keyword(s):  
Nuclear Morphology ◽  
Basal Keratinocytes ◽  
Chromatin Texture

Light scattering from cervical cells throughout neoplastic progression: influence of nuclear morphology, DNA content, and chromatin texture

2003 ◽  
Vol 8 (1) ◽  
pp. 7 ◽  
Author(s):  
Rebekah Drezek ◽  
Martial Guillaud ◽  
Thomas Collier ◽  
Iouri Boiko ◽  
Anais Malpica ◽  
...  
Keyword(s):  
Light Scattering ◽  
Dna Content ◽  
Nuclear Morphology ◽  
Neoplastic Progression ◽  
Chromatin Texture ◽  
Cervical Cells

An adrenocortical oncocytoma with unusual mitochondrial inclusions and cytoplasmic crystals

1994 ◽  
Vol 52 ◽  
pp. 250-251
Author(s):  
W.T. Gunning ◽  
G.D. Haselhuhn ◽  
E.R. Phillips ◽  
S.H. Selman
Keyword(s):  
Adrenal Gland ◽  
Salivary Glands ◽  
Mitotic Activity ◽  
Diagnostic Criteria ◽  
Vascular Invasion ◽  
Benign Neoplasm ◽  
Benign Tumors ◽  
Nuclear Morphology ◽  
Case Presentation ◽  
Microscopic Evidence

Within the last few years, adrenal cortical tumors with features concordant with the diagnostic criteria attributed to oncocytomas have been reported. To date, only nine reported cases exist in the literature. This report is the tenth case presentation of a presumptively benign neoplasm of the adrenal gland with a rare differentiation. Oncocytomas are well recognized benign tumors of the thyroid, parathyroid, and salivary glands and of the kidney. Other organs also give rise to these types of tumors, however with less frequency than the former sites. The characteristics generally used to classify a tumor as an oncocytoma include the following criteria: the tumor is 1) usually a solitary circumscribed mass with no gross nor microscopic evidence of metastasis (no tissue nor vascular invasion), 2) fairly bland in terms of mitotic activity and nuclear morphology, and 3) composed of large eosinophillic cells in which the cytoplasm is packed full of mitochondria (Figure 1).

scholarly journals Histomorphological Assessment of Formalin versus Nonformalin Fixatives in Diagnostic Surgical Pathology

2020 ◽  
Vol 12 (04) ◽  
pp. 271-275
Author(s):  
Jayaprakash Kubalady Shetty ◽  
Hannah Fathima Babu ◽  
Kishan Prasad Hosapatna Laxminarayana
Keyword(s):  
Methyl Alcohol ◽  
Potential Role ◽  
Tissue Architecture ◽  
Substantial Evidence ◽  
Diagnostic Pathology ◽  
Rapid Fixation ◽  
Chromatin Texture ◽  
Upper Respiratory ◽  
Potential Human Health

Abstract Introduction Fixation is the critical step in the preservation of tissues in diagnostic pathology. The formalin is an economical and excellent fixative with the inherent property of adequate fixation. The well-established side effects of formalin include mucosal irritation, upper respiratory diseases, and corrosive injury to the gastrointestinal tract. In addition, substantial evidence exists regarding the potential role of formaldehyde as a human carcinogen. The carcinogenic and toxic effects of formalin encourage searching for alternative fixatives for tissue fixation. However, “the formalin dogma” has severely hampered the search for alternative fixatives for many years. Material and Methods Ninety tissues of liver and skeletal muscle obtained during autopsies were immersed in adequate amounts of the following fixatives: formalin (10%), methyl alcohol (70%), and acetone (100%). The comparison among the three was made based on time for fixation, preservation of tissue architecture, cell borders, cytoplasm, nuclear contours, chromatin texture, and uniformity of staining. Results The tissue preserved in formalin undergoes rapid fixation compared with alcohol and acetone. The tissue architecture, cell border characteristics of alcohol and acetone was found satisfactory compared with formalin. The cytoplasm and nuclear contour were superior with the formalin. The chromatin texture and uniformity of staining were similar with all the three fixatives. Conclusion The formalin is considered superior to most of the parameters, whereas both methyl alcohol and acetone showed nearly equivalent scores. Hence, owing to the potential human health hazards and carcinogenicity of formalin, no rational reasons hamper the complete substitution of formalin with alternative fixatives such as alcohol and acetone in diagnostic pathology and medical research.

scholarly journals Habitat differences affect the nuclear morphology of the erythrocytes and the hepatic melanin in Leptodactylus fuscus (Anura) in the Brazilian Cerrado savanna

2021 ◽  
Author(s):  
Rhayane Alves Assis ◽  
Wadson Rodrigues Rezende ◽  
Cirley Gomes Araújo dos Santos ◽  
Marcelino Benvindo-Souza ◽  
Nathan Pereira Lima Amorim ◽  
...  
Keyword(s):  
Nuclear Morphology ◽  
Brazilian Cerrado ◽  
Habitat Differences ◽  
Cerrado Savanna

Testosterone exposure in prenatal life disrupts epithelial nuclear morphology, smooth muscle layer pattern, and FGF10 and Shh expression in prostate

Life Sciences ◽  
2021 ◽  
Vol 271 ◽  
pp. 119198
Author(s):  
Luana Araújo Manso ◽  
Barbara Costa Malmann Medeiros ◽  
Giovanna Amaral Rodrigues ◽  
Jordana Gomes Ramos ◽  
Mara Rúbia Marques ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Muscle Layer ◽  
Nuclear Morphology ◽  
Smooth Muscle Layer

scholarly journals Overexpression of PD‐L1 in gingival basal keratinocytes reduces periodontal inflammation in a ligature‐induced periodontitis model

2021 ◽  
Author(s):  
Keeratika Wongtim ◽  
Eri Ikeda ◽  
Tatsukuni Ohno ◽  
Shigenori Nagai ◽  
Shigeru Okuhara ◽  
...  
Keyword(s):  
Basal Keratinocytes ◽  
Periodontal Inflammation

Ultrafast Toluidine Blue Staining for Rapid On-Site Evaluation of Cytological Smears

2020 ◽  
Vol 64 (4) ◽  
pp. 375-377
Author(s):  
Ekkehard Hewer ◽  
Anja M. Schmitt
Keyword(s):  
Organic Solvents ◽  
Toluidine Blue ◽  
Critical Factor ◽  
Blue Staining ◽  
Nuclear Morphology ◽  
Hazardous Chemicals ◽  
Toluidine Blue Staining ◽  
Site Evaluation ◽  
The Rose

Rapid on-site evaluation (ROSE) is one of cytopathology’s “unique selling propositions.” The quality, speed, and ease of handling of the staining used is a critical factor for the efficacy of the ROSE procedure. Here, we describe a modification of rapid toluidine blue staining that can be performed within 25 s, provides excellent nuclear morphology, and is compatible with subsequent Papanicolaou staining of the slides. Furthermore, exposure to hazardous chemicals is minimized, as no organic solvents other than the alcohol-based fixative and glycerin for temporary mounting and coverslipping are required. We have used this protocol successfully in our ROSE practice and have not observed any discrepancies between toluidine blue- and permanent Papanicolaou-stained slides.

Insulator foci distance correlates with cellular and nuclear morphology in early Drosophila embryos

2021 ◽  
Vol 476 ◽  
pp. 189-199
Author(s):  
Mo Li ◽  
Qing Zhao ◽  
Ryan Belloli ◽  
Carly R. Duffy ◽  
Haini N. Cai
Keyword(s):  
Nuclear Morphology ◽  
Drosophila Embryos
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