In vitro antibiotic susceptibility patterns of Propionibacterium acnes isolated from acne patients: an Egyptian university hospital-based study

2012 ◽  
Vol 27 (12) ◽  
pp. 1546-1551 ◽  
Author(s):  
N.S.A. Abdel Fattah ◽  
Y.W. Darwish
Keyword(s):  
Antibiotic Susceptibility ◽  
Propionibacterium Acnes ◽  
University Hospital ◽  
Antibiotic Susceptibility Patterns ◽  
Susceptibility Patterns

scholarly journals Pediatric fever in neutropenia with bacteremia—Pathogen distribution and in vitro antibiotic susceptibility patterns over time in a retrospective single-center cohort study

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0246654
Author(s):  
Melina Stergiotis ◽  
Roland A. Ammann ◽  
Sara Droz ◽  
Christa Koenig ◽  
Philipp Kwame Abayie Agyeman
Keyword(s):  
Antimicrobial Activity ◽  
Cancer Patients ◽  
Pediatric Cancer ◽  
Antibiotic Susceptibility ◽  
Single Center ◽  
Pediatric Cancer Patients ◽  
Antibiotic Susceptibility Patterns ◽  
Susceptibility Patterns ◽  
Over Time

Background Fever in neutropenia (FN) is a potentially life-threatening complication of chemotherapy in pediatric cancer patients. The current standard of care at most institutions is emergency hospitalization and empirical initiation of broad-spectrum antibiotic therapy. Methods We analyzed in retrospect FN episodes with bacteremia in pediatric cancer patients in a single center cohort from 1993 to 2012. We assessed the distribution of pathogens, the in vitro antibiotic susceptibility patterns, and their trends over time. Results From a total of 703 FN episodes reported, we assessed 134 FN episodes with bacteremia with 195 pathogens isolated in 102 patients. Gram-positive pathogens (124, 64%) were more common than Gram-negative (71, 36%). This proportion did not change over time (p = 0.26). Coagulase-negative staphylococci (64, 32%), viridans group streptococci (42, 22%), Escherichia coli (33, 17%), Klebsiella spp. (10, 5%) and Pseudomonas aeruginosa (nine, 5%) were the most common pathogens. Comparing the in vitro antibiotic susceptibility patterns, the antimicrobial activity of ceftriaxone plus amikacin (64%; 95%CI: 56%-72%), cefepime (64%; 95%CI 56%-72%), meropenem (64%; 95%CI 56%-72), and piperacillin/tazobactam (62%; 95%CI 54%-70%), respectively, did not differ significantly. The addition of vancomycin to those regimens would have increased significantly in vitro activity to 99% for ceftriaxone plus amikacin, cefepime, meropenem, and 96% for piperacillin/tazobactam (p < 0.001). Conclusions Over two decades, we detected a relative stable pathogen distribution and found no relevant trend in the antibiotic susceptibility patterns. Different recommended antibiotic regimens showed comparable in vitro antimicrobial activity.

scholarly journals The In Vitro Antibiotic Susceptibility of Malaysian Isolates ofBurkholderia pseudomallei

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Norazah Ahmad ◽  
Rohaidah Hashim ◽  
Azura Mohd Noor
Keyword(s):  
Antibiotic Susceptibility ◽  
Burkholderia Pseudomallei ◽  
Inhibitory Concentration ◽  
Test Method ◽  
Amoxicillin Clavulanic Acid ◽  
Antibiotic Susceptibility Patterns ◽  
Potential Alternative ◽  
Ciprofloxacin Resistance ◽  
Susceptibility Patterns

Acute melioidosis may present as localised or septicaemic infections and can be fatal if left untreated.Burkholderia pseudomalleiresistant to antibiotics used for the treatment of melioidosis had been reported. The aim of this study was to determine the in vitro antibiotic susceptibility patterns ofBurkholderia pseudomalleiisolated in Malaysia to a panel of antibiotics used for the treatment of melioidosis and also to potential alternative antibiotics such as tigecycline, ampicillin/sulbactam, and piperacillin/tazobactam. A total of 170Burkholderia pseudomalleiisolates were subjected to minimum inhibitory concentration determination usingE-test method to eleven antibiotics. All isolates were sensitive to meropenem and piperacillin/tazobactam. For ceftazidime, imipenem, amoxicillin/clavulanic acid, and doxycycline resistance was observed in 1 isolate (0.6%) for each of the antibiotics. Trimethoprim/sulfamethoxazole resistance was observed in 17 (10%) isolates. For other antibiotics, ampicillin/sulbactam, chloramphenicol, tigecycline, and ciprofloxacin resistance were observed in 1 (0.6%), 6 (3.5%), 60 (35.3%) and 98 (57.7%) isolates respectively. One isolate B170/06 exhibited resistance to 4 antibiotics, namely, ciprofloxacin, chloramphenicol, trimethoprim/sulfamethoxazole, and tigecycline. In conclusion, the Malaysian isolates were highly susceptible to the current antibiotics used in the treatment of melioidosis in Malaysia. Multiple resistances to the antibiotics used in the maintenance therapy are the cause for a concern.

In vitro Antibiotic Susceptibility Patterns of Ornithobacterium rhinotracheale from Commercial Chickens in Argentina#

2016 ◽  
Vol 15 (8) ◽  
pp. 293-296
Author(s):  
Carlos D. Gornatti Churria ◽  
Panayiotis Loukopoulo ◽  
German B. Vigo ◽  
Pablo Sansalone ◽  
Mariana A. Machuca ◽  
...  
Keyword(s):  
Antibiotic Susceptibility ◽  
Antibiotic Susceptibility Patterns ◽  
Susceptibility Patterns ◽  
Ornithobacterium Rhinotracheale ◽  
Commercial Chickens
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