Dual protein kinase C alpha and beta inhibitors and diabetic kidney disease: a revisited therapeutic target for future clinical trials

Daisuke Koya

doi:10.1111/jdi.12154

Dual protein kinase C alpha and beta inhibitors and diabetic kidney disease: a revisited therapeutic target for future clinical trials

Journal of Diabetes Investigation ◽

10.1111/jdi.12154 ◽

2013 ◽

Vol 5 (2) ◽

pp. 147-148 ◽

Cited By ~ 5

Author(s):

Daisuke Koya

Keyword(s):

Clinical Trials ◽

Protein Kinase C ◽

Protein Kinase ◽

Kidney Disease ◽

Therapeutic Target ◽

Diabetic Kidney Disease ◽

Diabetic Kidney ◽

Kinase C ◽

Protein Kinase C Alpha

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Protein kinase C- inhibition attenuates the progression of nephropathy in non-diabetic kidney disease

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfn729 ◽

2009 ◽

Vol 24 (6) ◽

pp. 1782-1790 ◽

Cited By ~ 9

Author(s):

D. J. Kelly ◽

A. J. Edgley ◽

Y. Zhang ◽

K. Thai ◽

S. M. Tan ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Kidney Disease ◽

Diabetic Kidney Disease ◽

Diabetic Kidney ◽

Kinase C

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Protein kinase C-β inhibition for diabetic kidney disease

Diabetes Research and Clinical Practice ◽

10.1016/j.diabres.2008.09.041 ◽

2008 ◽

Vol 82 ◽

pp. S70-S74 ◽

Cited By ~ 27

Author(s):

Katherine R. Tuttle

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Kidney Disease ◽

Diabetic Kidney Disease ◽

Diabetic Kidney ◽

Kinase C

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Protein kinase C alpha and epsilon reduce Ca-sensitivity of force development in human myocardium by phosphorylation of troponin

European Journal of Heart Failure Supplements ◽

10.1016/s1567-4215(08)60143-5 ◽

2008 ◽

Vol 7 ◽

pp. 50-50

Author(s):

J VANDERVELDEN ◽

V KOOIJ ◽

R ZAREMBA ◽

N BOONTJE ◽

G STIENEN

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Human Myocardium ◽

Force Development ◽

Kinase C ◽

Protein Kinase C Alpha ◽

Ca Sensitivity

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Faculty Opinions recommendation of Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718106805.793488943 ◽

2013 ◽

Author(s):

Avri Ben-Ze'ev

Keyword(s):

Breast Cancer ◽

Stem Cells ◽

Protein Kinase C ◽

Protein Kinase ◽

Cancer Stem Cells ◽

Therapeutic Target ◽

Breast Cancer Stem Cells ◽

Kinase C

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Protein Kinase C – Possible Therapeutic Target to Treat Cardiovascular Diseases

Cardiovascular & Haematological Disorders - Drug Targets ◽

10.2174/187152910793743869 ◽

2010 ◽

Vol 10 (4) ◽

pp. 292-308 ◽

Cited By ~ 16

Author(s):

Yamini S. Bynagari-Settipalli ◽

Ramya Chari ◽

Laurie Kilpatrick ◽

Satya P. Kunapuli

Keyword(s):

Protein Kinase C ◽

Cardiovascular Diseases ◽

Protein Kinase ◽

Therapeutic Target ◽

Kinase C

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Evaluating the current status of protein kinase C (PKC)-protein kinase D (PKD) signalling axis as a novel therapeutic target in ovarian cancer

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer ◽

10.1016/j.bbcan.2020.188496 ◽

2021 ◽

Vol 1875 (1) ◽

pp. 188496

Author(s):

Komal Tyagi ◽

Adhiraj Roy

Keyword(s):

Ovarian Cancer ◽

Protein Kinase C ◽

Protein Kinase ◽

Therapeutic Target ◽

Current Status ◽

Protein Kinase D ◽

Kinase C ◽

Novel Therapeutic

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Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-alpha and -delta and not by protein kinase C-beta II, -epsilon, -zeta, and -eta.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)80701-7 ◽

1993 ◽

Vol 268 (27) ◽

pp. 20110-20115

Author(s):

H Mischak ◽

J.H. Pierce ◽

J Goodnight ◽

M.G. Kazanietz ◽

P.M. Blumberg ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Phorbol Ester ◽

Myeloid Differentiation ◽

Kinase C ◽

Protein Kinase C Alpha ◽

Protein Kinase C Beta

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Biologically active milli-calpain associated with caveolae is involved in a spatially compartmentalised signalling involving protein kinase C alpha and myristoylated alanine-rich C-kinase substrate (MARCKS)

The International Journal of Biochemistry & Cell Biology ◽

10.1016/j.biocel.2005.04.010 ◽

2005 ◽

Vol 37 (9) ◽

pp. 1900-1910 ◽

Cited By ~ 19

Author(s):

Sébastien Goudenege ◽

Sylvie Poussard ◽

Sandrine Dulong ◽

Patrick Cottin

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Biologically Active ◽

Kinase Substrate ◽

Kinase C ◽

Protein Kinase C Alpha

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Enhanced activity of an antisense oligonucleotide targeting murine protein kinase C-alpha by the incorporation of 2'-O-propyl modifications

Nucleic Acids Research ◽

10.1093/nar/24.3.411 ◽

1996 ◽

Vol 24 (3) ◽

pp. 411-417 ◽

Cited By ~ 43

Author(s):

R. McKay

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Antisense Oligonucleotide ◽

Kinase C ◽

Enhanced Activity ◽

Protein Kinase C Alpha

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Calcium‐dependent protein kinase C alpha and the frequency‐dependent increase in phosphorylation of troponin I in failing hearts

The FASEB Journal ◽

10.1096/fasebj.22.1_supplement.751.14 ◽

2008 ◽

Vol 22 (S1) ◽

Author(s):

Regis R. Lamberts ◽

Nazha Hamdani ◽

Lori A. Walker ◽

Pieter P. Tombe ◽

Jolanda Velden ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Troponin I ◽

Dependent Protein Kinase ◽

Frequency Dependent ◽

Calcium Dependent ◽

Kinase C ◽

Dependent Protein ◽

Protein Kinase C Alpha ◽

Calcium Dependent Protein Kinase

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