Effect of Schneiderian membrane integrity on bone formation in sinus augmentation: An experimental study in rabbits

2021 ◽  
Author(s):  
Jeong‐Won Paik ◽  
Jae‐Kook Cha ◽  
Young‐Woo Song ◽  
Daniel S. Thoma ◽  
Ronald E. Jung ◽  
...  
Keyword(s):  
Experimental Study ◽  
Bone Formation ◽  
Membrane Integrity ◽  
Sinus Augmentation ◽  
Schneiderian Membrane

scholarly journals Maxillary Sinus Augmentation Using Ceramic Alloplastic Granules or Paste: An Experimental Study in Rabbits

2021 ◽  
Vol 9 (6) ◽  
pp. 65
Author(s):  
Michael Medeiros Costa ◽  
Daniele Botticelli ◽  
Ofer Moses ◽  
Yuki Omori ◽  
Shigeo Fujiwara ◽  
...  
Keyword(s):  
Bone Formation ◽  
Maxillary Sinus ◽  
Biological Behavior ◽  
Collagen Membrane ◽  
Alloplastic Material ◽  
New Bone Formation ◽  
Sinus Augmentation ◽  
Beta Tricalcium Phosphate ◽  
Sinus Lifting ◽  
Points Of View

Background: Due to the lack of data comparing the biological behavior of two formulations, granules and paste, of alloplastic graft from microtomographic and histomorphometric points of view, the aim of the present experiment was to compare the histomorphometric and microtomographic healing of two formulations, i.e., granules (MR sites) or paste (MR-inject sites) of an alloplastic graft composed of a combination of beta-tricalcium phosphate and hydroxyapatite used for maxillary sinus lifting. Methods: A sinus lifting procedure was carried out bilaterally in 20 rabbits, and the elevated space was filled with either paste or granules of an alloplastic material. A collagen membrane was placed on the antrostomy and the animals were euthanized after 2 or 10 weeks, 10 animals each group. Microtomographic and histological analyses were performed. Results: Higher proportions of new bone formation were found at the MR, compared to the MR-inject sites both after 2 weeks (2.65 ± 2.89% vs. 0.08 ± 0.12%; p < 0.01) and 10 weeks of healing (34.20 ± 13.86 vs. 23.28 ± 10.35%; p = 0.022). Conclusions: It was concluded that new bone formation was faster in the MR sites, compared to the MR-inject. However, a longer time of healing should be allowed to make final conclusions about the efficiency in bone formation of the paste formulation of the biomaterial used in the present study.

Bone formation in sinus augmentation procedures using autologous bone, porcine bone, and a 50 : 50 mixture: a human clinical and histological evaluation at 2 months

2014 ◽  
Vol 26 (10) ◽  
pp. 1180-1184 ◽  
Author(s):  
Michele Cassetta ◽  
Vittoria Perrotti ◽  
Sabrina Calasso ◽  
Adriano Piattelli ◽  
Bruna Sinjari ◽  
...  
Keyword(s):  
Bone Formation ◽  
Histological Evaluation ◽  
Sinus Augmentation ◽  
Autologous Bone

Experimental study of bone formation around a titanium rod with β- tricalcium phosphate and prostaglandin E2 receptor agonists

2005 ◽  
Vol 10 (3) ◽  
pp. 308-314 ◽  
Author(s):  
Michinaga Masuzawa ◽  
Moroe Beppu ◽  
Shoji Ishii ◽  
Yuichiro Oyake ◽  
Haruhito Aoki ◽  
...  
Keyword(s):  
Experimental Study ◽  
Bone Formation ◽  
Prostaglandin E2 ◽  
Tricalcium Phosphate ◽  
Receptor Agonists ◽  
Prostaglandin E2 Receptor

Bone formation in peri-implant defects grafted with microparticles: a pilot animal experimental study

2014 ◽  
Vol 41 (10) ◽  
pp. 990-998 ◽  
Author(s):  
Tobias Moest ◽  
Franz Koehler ◽  
Christopher Prechtl ◽  
Christian Schmitt ◽  
Georg Watzek ◽  
...  
Keyword(s):  
Experimental Study ◽  
Bone Formation ◽  
Animal Experimental Study

Influence of Demineralized Bone Matrix's Embryonic Origin on Bone Formation: An Experimental Study in Rats

2003 ◽  
Vol 5 (3) ◽  
pp. 184-192 ◽  
Author(s):  
Andreas Stavropoulos ◽  
Lambros Kostopoulos ◽  
Nicolaos Mardas ◽  
Thorkild Karring
Keyword(s):  
Experimental Study ◽  
Bone Formation ◽  
Embryonic Origin ◽  
Demineralized Bone

scholarly journals Effectiveness of Platelet-Rich Fibrin as an Adjunctive Material to Bone Graft in Maxillary Sinus Augmentation: A Meta-Analysis of Randomized Controlled Trails

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Ruimin Liu ◽  
Mingdong Yan ◽  
Sulin Chen ◽  
Wenxiu Huang ◽  
Dong Wu ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Bone Formation ◽  
Bone Graft ◽  
Bone Substitute ◽  
Meta Analysis ◽  
New Bone Formation ◽  
Sinus Augmentation ◽  
Platelet Rich Fibrin ◽  
Randomized Controlled ◽  
Tissue Area

Purpose. To date, it remains unknown whether the addition of platelet-rich fibrin (PRF) to bone grafts actually improves the effectiveness of maxillary sinus augmentation. This study aimed to perform a meta-analysis to evaluate the efficacy of PRF in sinus lift.Materials and Methods. PubMed, Embase, and the Cochrane Library were searched. Randomized controlled studies were identified. The risk of bias was evaluated using the Cochrane Collaboration tool.Results. Five RCTs were included in our meta-analysis. Clinical, radiographic, and histomorphometric outcomes were considered. No implant failure or graft failure was detected in all included studies within the follow-up period. The percentage of contact length between newly formed bone substitute and bone in the PRF group was lower but lacked statistical significance (3.90%, 95% CI, -2.91% to 10.71%). The percentages of new bone formation (-1.59%, 95% CI, -5.36% to 2.18%) and soft-tissue area (-3.73%, 95% CI, -10.11% to 2.66%) were higher in the PRF group but were not significantly different. The percentage of residual bone graft was not significant in either group (4.57%, 95% CI, 0% to 9.14%).Conclusions. Within the limitations of this review, it was concluded that there were no statistical differences in survival rate, new bone formation, contact between newly formed bone and bone substitute, percentage of residual bone graft (BSV/TV), and soft-tissue area between the non-PRF and PRF groups. Current evidence supporting the necessity of adding PRF to bone graft in sinus augmentation is limited.

scholarly journals Collagenated Synthetic Bone Substitute Material for Sinus Floor Elevation at Sites with a Perforated Schneiderian Membrane

2020 ◽  
Vol 9 (11) ◽  
pp. 3764
Author(s):  
Sangyup Kim ◽  
Jong-Hyuk Chung ◽  
Seung-Yun Shin ◽  
Seung-Il Shin ◽  
Ji-Youn Hong ◽  
...  
Keyword(s):  
Bone Formation ◽  
Dimensional Stability ◽  
Bone Substitute ◽  
Control Group ◽  
New Bone Formation ◽  
Bone Substitute Material ◽  
Sinus Floor Elevation ◽  
Schneiderian Membrane ◽  
Sinus Floor ◽  
Substitute Material

Schneiderian membrane perforation (SMP) is the most common complication during sinus floor elevation (SFE). Conventional methods to repair SMP, such as using a collagen barrier, may be clinically demanding. The aim of the present study was to compare the effects of collagenated bone substitute materials with and without a collagen barrier to repair SMP during SFE in terms of new bone formation and dimensional stability. In 12 rabbits, intentional SMP was made during bilateral SFE. The rabbits were randomly assigned under two groups: the control group, in which the sinus was repaired with a collagen barrier, and the test group, in which the sinus was repaired without a collagen barrier. Collagenated bone substitute material was grafted in both groups. Healing periods of 2 weeks and 4 weeks were provided in both groups. There were no adverse clinical events. Histology revealed that the Schneiderian membrane had atrophied with loss of cilia and serous glands in both groups at 4 weeks. Histomorphometry revealed that the newly formed bone (test: 0.42 ± 0.17 mm2, control: 0.36 ± 0.18 mm2 at 2 weeks; test: 1.21 ± 0.36 mm2, control: 1.23 ± 0.55 mm2 at 4 weeks) or total augmented area did not significantly differ between the two groups at either time points (p > 0.05). In conclusion, collagenated bone substitute material without a collagen barrier demonstrated similar new bone formation and dimensional stability as that with a collagen barrier in repairing SMP.

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