scholarly journals Histological and micro-computed tomography evaluations of newly formed bone after maxillary sinus augmentation using a xenograft with similar density and mineral content of bone: An experimental study in rabbits

2018 ◽  
Vol 4 (6) ◽  
pp. 284-290 ◽  
Author(s):  
Takahisa Iida ◽  
Erick Ricardo Silva ◽  
Niklaus P. Lang ◽  
Karol Alí Apaza Alccayhuaman ◽  
Daniele Botticelli ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Experimental Study ◽  
Maxillary Sinus ◽  
Mineral Content ◽  
Micro Computed Tomography ◽  
Sinus Augmentation ◽  
Maxillary Sinus Augmentation ◽  
Similar Density

scholarly journals Biphasic Calcium Phosphate Biomaterials: Stem Cell-Derived Osteoinduction or In Vivo Osteoconduction? Novel Insights in Maxillary Sinus Augmentation by Advanced Imaging

Materials ◽  
2021 ◽  
Vol 14 (9) ◽  
pp. 2159
Author(s):  
Giovanna Iezzi ◽  
Antonio Scarano ◽  
Luca Valbonetti ◽  
Serena Mazzoni ◽  
Michele Furlani ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Maxillary Sinus ◽  
Biphasic Calcium Phosphate ◽  
Calcium Phosphates ◽  
Three Dimensional ◽  
Sinus Augmentation ◽  
Native Bone ◽  
Maxillary Sinus Augmentation ◽  
Posterior Maxilla

Maxillary sinus augmentation is often necessary prior to implantology procedure, in particular in cases of atrophic posterior maxilla. In this context, bone substitute biomaterials made of biphasic calcium phosphates, produced by three-dimensional additive manufacturing were shown to be highly biocompatible with an efficient osteoconductivity, especially when combined with cell-based tissue engineering. Thus, in the present research, osteoinduction and osteoconduction properties of biphasic calcium-phosphate constructs made by direct rapid prototyping and engineered with ovine-derived amniotic epithelial cells or amniotic fluid cells were evaluated. More in details, this preclinical study was performed using adult sheep targeted to receive scaffold alone (CTR), oAFSMC, or oAEC engineered constructs. The grafted sinuses were explanted at 90 days and a cross-linked experimental approach based on Synchrotron Radiation microCT and histology analysis was performed on the complete set of samples. The study, performed taking into account the distance from native surrounding bone, demonstrated that no significant differences occurred in bone regeneration between oAEC-, oAFMSC-cultured, and Ctr samples and that there was a predominant action of the osteoconduction versus the stem cells osteo-induction. Indeed, it was proven that the newly formed bone amount and distribution decreased from the side of contact scaffold/native bone toward the bulk of the scaffold itself, with almost constant values of morphometric descriptors in volumes more than 1 mm from the border.

Maxillary Sinus Augmentation with a New Xenograft: A Randomized Controlled Clinical Trial

2014 ◽  
Vol 17 ◽  
pp. e586-e593 ◽  
Author(s):  
Mônica Diuana Calasans-Maia ◽  
Carlos Fernando de A. B. Mourão ◽  
Adriana Terezinha Neves Novellino Alves ◽  
Suelen Cristina Sartoretto ◽  
Marcelo José P. G. de Uzeda ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Maxillary Sinus ◽  
Controlled Clinical Trial ◽  
Randomized Controlled Clinical Trial ◽  
Sinus Augmentation ◽  
Randomized Controlled ◽  
Maxillary Sinus Augmentation
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