Dysregulation of genes and microRNAs in localized aggressive periodontitis

2020 ◽  
Vol 47 (11) ◽  
pp. 1317-1325
Author(s):  
Jussara Gonçalves Fernandes ◽  
Lorri Ann Morford ◽  
Peter Lloyd Harrison ◽  
Theodora Kompotiati ◽  
Hong Huang ◽  
...  
Keyword(s):  
Aggressive Periodontitis ◽  
Localized Aggressive Periodontitis

Comparative evaluation of amoxicillin plus metronidazole and doxycycline alone in the nonsurgical treatment of localized aggressive periodontitis

2014 ◽  
Vol 5 (3) ◽  
pp. 112
Author(s):  
Rajasekhar Nutalapati ◽  
SureshKumar Kasagani ◽  
NarendraDev Jampani ◽  
RameshBabu Mutthineni ◽  
Srikanth Chintala ◽  
...  
Keyword(s):  
Comparative Evaluation ◽  
Aggressive Periodontitis ◽  
Nonsurgical Treatment ◽  
Localized Aggressive Periodontitis

One-year follow-up of the immune profile in serum and selected sites of generalized and localized aggressive periodontitis

Cytokine ◽  
2019 ◽  
Vol 116 ◽  
pp. 27-37 ◽  
Author(s):  
E.S. Martins ◽  
J.B. César-Neto ◽  
E. Albuquerque-Souza ◽  
E.S. Rebeis ◽  
M. Holzhausen ◽  
...  
Keyword(s):  
Aggressive Periodontitis ◽  
Immune Profile ◽  
Localized Aggressive Periodontitis ◽  
One Year

scholarly journals Clinical Evaluation of Intrabony Defects in Localized Aggressive Periodontitis Patients with and without Bioglass- An In-vivo Study

2012 ◽  
Vol 10 (1) ◽  
pp. 7-10
Author(s):  
KV Satyanarayana ◽  
BR Anuradha ◽  
G Srikanth ◽  
P Mohan Chandra ◽  
T Anupama ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Test Group ◽  
Gingival Recession ◽  
Aggressive Periodontitis ◽  
Control Group ◽  
Defect Depth ◽  
Clinical Attachment Level ◽  
Probing Depth ◽  
Localized Aggressive Periodontitis ◽  
Attachment Level

Background Aggressive periodontitis is a specific type of periodontitis with clearly identifiable clinical characteristics such as “rapid attachment loss, bone destruction” and “familial aggregation”. Regeneration of mineralized tissues affected by aggressive periodontitis comprises a major scientific and clinical challenge. In recent years some evidence has been provided that bioactive glass is also capable of supporting the regenerative healing of periodontal lesions. Objective The aim of this clinical and radiological prospective study was to evaluate the efficacy of bioactive glass in the treatment of intra-bony defects in patients with localized aggressive periodontitis. Methods Twelve localized aggressive periodontitis patients with bilaterally located three-walled intra-bony defect depth ? 2 mm, preoperative probing depths ? 5 mm were randomly treated either with the bioactive glass or without the bioactive glass. The clinical parameters plaque index, gingival index, probing depth, gingival recession, clinical attachment level, and mobility were recorded prior to surgery as well as 12 months after surgery. Intraoral radiographs were digitized to evaluate the bone defect depth at baseline and 12 months after the surgery. Results After 12 months, a reduction in probing depth of 3.92 + 0.313 mm (P <0.001) and a gain in clinical attachment level of 4.42+0358mm (P <0.001) were registered in the test group. In the control group, a reduction in probing depth of 2.5 +0.230mm (P <0.001) and a gain in clinical attachment level of 2.58 + 0.149 mm (P<0.001) was recorded. Radiographically, the defects were found to be filled by 2.587 + 0.218 mm (P <0.001) in the test group and by 0.1792 + 0.031mm (P <0.001) in the control group. Changes in gingival recession showed no significant differences. . Conclusion Highly significant improvements in the parameters Probing depth, Clinical attachment level, and Bone defect depth were recorded after 12 months, with regenerative material. KATHMANDU UNIVERSITY MEDICAL JOURNAL  VOL.10 | NO. 1 | ISSUE 37 | JAN - MAR 2012 | 11-15 DOI: http://dx.doi.org/10.3126/kumj.v10i1.6906

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