scholarly journals TTN/OBSCN ‘Double‐Hit’ predicts favourable prognosis, ‘immune‐hot’ subtype and potentially better immunotherapeutic efficacy in colorectal cancer

2021 ◽  
Author(s):  
Zaoqu Liu ◽  
Libo Wang ◽  
Chunguang Guo ◽  
Long Liu ◽  
Dechao Jiao ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Favourable Prognosis ◽  
Double Hit

scholarly journals Serological immune response against ADAM10 pro-domain is associated with favourable prognosis in stage III colorectal cancer patients

Oncotarget ◽  
2016 ◽  
Vol 7 (48) ◽  
pp. 80059-80076 ◽  
Author(s):  
Sheila María Álvarez-Fernández ◽  
Marco Barbariga ◽  
Luca Cannizzaro ◽  
Carlo Vittorio Cannistraci ◽  
Laura Hurley ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Immune Response ◽  
Cancer Patients ◽  
Stage Iii ◽  
Favourable Prognosis ◽  
Colorectal Cancer Patients

scholarly journals Prognostic Value of Microvascular Density in Dukes A and B (T1–T4, N0, M0) Colorectal Carcinomas

2009 ◽  
Vol 2009 ◽  
pp. 1-7 ◽  
Author(s):  
Rafael Uribarrena A ◽  
Javier Ortego ◽  
Javier Fuentes ◽  
Nuria Raventós ◽  
Pilar Parra ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Prognostic Factor ◽  
Significant Influence ◽  
Prognostic Value ◽  
Microvascular Density ◽  
Colorectal Carcinomas ◽  
Favourable Prognosis ◽  
Vascular Area ◽  
The Mean

Background. Aproximatelly 30% of patients operated on for colorectal cancer (CRC), with an expectedly favourable prognosis (Dukes A-B/T1–T4, N0, M0) suffer recurrence and/or die.Method. In order to determine if tumor microvascular density (MVD) is a prognostic factor in CRC, samples from tumors of 104 Dukes A-B CRC patients were retrospectively studied. Immunohistochemistry was performed for anti-CD34 antibody to visualize tumor vascularisation. MVD was expressed as the total number of vessels and as the percentage of microvascular area. We calculated MVD with a morphometry program and performed descriptive, bivariate, and survival statistics.Results. The mean number of vessels was 37.37/200x field, and the mean vascular area was the 3.972%. 30% of the patients with<37 vessels/field, and 21% of the patients with>37 vessels/field, experienced recurrence/death. The 35% of patients with<4% of vascular area died following recurrence, compared with 14% of patients with ≥4% of vascular area. These differences in % of vascular area were statistically significant.Conclusion. MVD expressed as the total number of vessels had no a statistically significant influence on the evolution of CRC. However, neoplasias with a greater % of vascular were associated to a better outcome.

Gremlin1 expression associates with serrated pathway and favourable prognosis in colorectal cancer

2016 ◽  
Vol 69 (5) ◽  
pp. 831-838 ◽  
Author(s):  
Ari Pelli ◽  
Juha P Väyrynen ◽  
Kai Klintrup ◽  
Jyrki Mäkelä ◽  
Markus J Mäkinen ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Serrated Pathway ◽  
Favourable Prognosis

Deletion mapping on chromosome 6 in colorectal cancer associated with ulcerative colitis

2001 ◽  
Vol 120 (5) ◽  
pp. A121-A122
Author(s):  
T EZAKI ◽  
M WATANABE ◽  
S FUNAKOSHI ◽  
M NAGANUMA ◽  
T AZUMA ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Ulcerative Colitis ◽  
Deletion Mapping ◽  
Chromosome 6

Predicting adherence to colorectal cancer surveillance after plypectomy

2001 ◽  
Vol 120 (5) ◽  
pp. A602-A602
Author(s):  
S RAWL ◽  
S BLACKBURN ◽  
L HACKWARD ◽  
N FINEBERG ◽  
T IMPERIALE ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Surveillance ◽  
Colorectal Cancer Surveillance

Urokinase type plasminogen activator and inhibitor type-1 plasma levels in colorectal cancer

2001 ◽  
Vol 120 (5) ◽  
pp. A599-A600 ◽  
Author(s):  
L HERSZENYI ◽  
F FARINATI ◽  
G ISTVAN ◽  
M PAOLI ◽  
G ROVERONI ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Plasminogen Activator ◽  
Plasma Levels ◽  
Type Plasminogen Activator ◽  
Urokinase Type Plasminogen Activator ◽  
Inhibitor Type

A panel of mono- and dinucleotide microsatellite markers is required for reliable determination of the MSI status in colorectal cancer

2001 ◽  
Vol 120 (5) ◽  
pp. A599-A599
Author(s):  
C ARNOLD ◽  
A GOEL ◽  
J CARETHERS ◽  
L WASSERMAN ◽  
C COMPTON ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Markers ◽  
Reliable Determination
Sign in / Sign up

Export Citation Format

Share Document