scholarly journals A critical role of the K Ca 3.1 channel in mechanical stretch‐induced proliferation of rat bone marrow‐derived mesenchymal stem cells

2020 ◽  
Vol 24 (6) ◽  
pp. 3739-3744
Author(s):  
Xiaoling Jia ◽  
Hao Su ◽  
Xinlan Chen ◽  
Yangbi Huang ◽  
Yufan Zheng ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Critical Role ◽  
Mechanical Stretch ◽  
Rat Bone

Role of 5-azacytidine in the differentiation of rat bone marrow mesenchymal stem cells into cardiomyogenic cells

2012 ◽  
Vol 35 (1) ◽  
pp. 23-33
Author(s):  
Samy Hosny Hammed ◽  
Amany Mohamed El Shawarby ◽  
Mohamed Abd Elrahman Ahmed ◽  
Mohamed Kamel Abo Golayel ◽  
Asmaa Abd Elmonem Mohamed
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Marrow Mesenchymal Stem Cells ◽  
Rat Bone

Mechanical stretch promotes proliferation of rat bone marrow mesenchymal stem cells

2007 ◽  
Vol 58 (2) ◽  
pp. 271-277 ◽  
Author(s):  
Guanbin Song ◽  
Yang Ju ◽  
Xiaodong Shen ◽  
Qing Luo ◽  
Yisong Shi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Mechanical Stretch ◽  
Marrow Mesenchymal Stem Cells ◽  
Rat Bone

scholarly journals The Critical Role of Long Noncoding RNA in Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Xiaoling Qiu ◽  
Bo Jia ◽  
Xiang Sun ◽  
Weitao Hu ◽  
Hongxing Chu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Osteogenic Differentiation ◽  
Critical Role ◽  
Human Bone ◽  
Differentially Expressed ◽  
Human Bone Marrow ◽  
Marrow Mesenchymal Stem Cells

Objective. Long noncoding RNAs (lncRNAs) have been demonstrated to regulate many biological processes including differentiation. However, their role in osteogenic differentiation was poorly known. Materials and Methods. In this study, we first globally profiled the differentially expressed lncRNAs and mRNAs during osteogenic differentiation of human bone marrow mesenchymal stem cells (hBMMSCs). Bioinformatics analysis was performed to further analyze these significantly changed molecules. Then the role of lncRNA ENST00000502125.2 in the osteogenic differentiation was determined. Results. A number of lncRNAs and mRNAs were significantly differentially expressed during hBMMSC osteogenic differentiation. Among them, 433 lncRNAs and 956 mRNAs were continuously upregulated, while 232 lncRNAs and 229 mRNAs were continuously downregulated. Gene Ontology and KEGG (Kyoto Encyclopedia of Genes and Genomes) analysis showed that carbohydrate derivative binding and complement and coagulation cascades were most correlated molecular function and pathway, respectively. Downregulation of lncRNA ENST00000502125.2 promoted the osteogenic differentiation of hBMMSCs, and opposite results were found when lncRNA ENST00000502125.2 was upregulated. Conclusions. lncRNAs play a critical role in the osteogenic differentiation of hBMMSCs and targeting lncRNA ENST00000502125.2 might be a promising strategy to promote osteogenic differentiation.

Long-term in vivo imaging of human angiogenesis: Critical role of bone marrow-derived mesenchymal stem cells for the generation of durable blood vessels

2008 ◽  
Vol 75 (3) ◽  
pp. 308-314 ◽  
Author(s):  
Laura Sanz ◽  
Patricia Santos-Valle ◽  
Vanesa Alonso-Camino ◽  
Clara Salas ◽  
Antonio Serrano ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Blood Vessels ◽  
In Vivo Imaging ◽  
Critical Role

Investigating the effect of lead acetate on rat bone marrow-derived mesenchymal stem cells toxicity: Role of apoptosis

2011 ◽  
Vol 21 (3) ◽  
pp. 225-230 ◽  
Author(s):  
Ali M. Sharifi ◽  
Roshanak Ghazanfari ◽  
Neda Tekiyehmaroof ◽  
Mohammad A. Sharifi
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Lead Acetate ◽  
Rat Bone

scholarly journals Bone marrow mesenchymal stem cells inhibited bleomycin-induced lung fibrosis

RSC Advances ◽  
2017 ◽  
Vol 7 (78) ◽  
pp. 49498-49504
Author(s):  
Jiang Nan ◽  
Zhao Zhongyan
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Protective Effect ◽  
Lung Fibrosis ◽  
Critical Role ◽  
Marrow Mesenchymal Stem Cells

The present study was performed to evaluate the protective effect of bone marrow mesenchymal stem cells (BMSCs), TLR2-silencing BMSCs (BMSCTLR2−/−), on bleomycin (BLM)-induced lung fibrosis and elucidate the critical role of TLR2 during the process.

Sign in / Sign up

Export Citation Format

Share Document