Percutaneous retrieval of a dislocated LAmbre left atrial appendage occluder in a canine model

2020 ◽  
Vol 31 (2) ◽  
pp. 529-535 ◽  
Author(s):  
Guangji Wang ◽  
Bin Kong ◽  
Yu Liu ◽  
He Huang
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Canine Model ◽  
Atrial Appendage ◽  
Percutaneous Retrieval

scholarly journals Percutaneous Retrieval of a Left Atrial Appendage Closure Device

2021 ◽  
Author(s):  
Achille Gaspardone ◽  
Maria Benedetta Giannico ◽  
Roberto Cancellieri ◽  
Laura Velardi ◽  
Antonio Giuseppe Posteraro ◽  
...  
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Closure Device ◽  
Left Atrial Appendage Closure ◽  
Percutaneous Retrieval

scholarly journals Percutaneous Retrieval of Emboli Zed Left Atrial Appendage Occluder Followed by Re-implantation of Different Type Device

2021 ◽  
Vol 05 (05) ◽  
Author(s):  
Peruga JZ ◽  
Ćwiek-Rębowska E ◽  
Szymczyk E ◽  
Jankowski L ◽  
Kasprzak J
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Percutaneous Retrieval ◽  
Type Device

scholarly journals LONG-TERM SAFETY AND BIOCOMPATIBILITY OF THE COHEREX WAVECRESTTM LEFT ATRIAL APPENDAGE OCCLUDER IN A CANINE MODEL

2014 ◽  
Vol 63 (12) ◽  
pp. A1677 ◽  
Author(s):  
Yanping Cheng ◽  
Jennifer McGregor ◽  
Daryl Edmiston ◽  
Robert Sommer ◽  
William Gray ◽  
...  
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Canine Model ◽  
Atrial Appendage

First in vivo evaluation of a flexible self-apposing left atrial appendage closure device in the canine model

2015 ◽  
Vol 86 (1) ◽  
pp. 173-181 ◽  
Author(s):  
Yanping Cheng ◽  
Gerard Conditt ◽  
Genghua Yi ◽  
Armando Tellez ◽  
Michael Corcoran ◽  
...  
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Canine Model ◽  
Atrial Appendage ◽  
Closure Device ◽  
Left Atrial Appendage Closure ◽  
In Vivo Evaluation

scholarly journals Percutaneous retrieval of a dislodged watchman left atrial appendage closure device

2016 ◽  
Vol 1 (3) ◽  
pp. 48
Author(s):  
Jiangtao Yu ◽  
Shaofeng Guan ◽  
Manuela Muenzel ◽  
Erich Duenninger
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Closure Device ◽  
Left Atrial Appendage Closure ◽  
Percutaneous Retrieval

scholarly journals Preclinical Assessment of a Novel Conformable Foam-Based Left Atrial Appendage Closure Device

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Robert J. Sommer ◽  
Ronald Lamport ◽  
David Melanson ◽  
Carol Devellian ◽  
Andy Levine ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Left Atrial ◽  
Left Atrial Appendage ◽  
Canine Model ◽  
Atrial Appendage ◽  
Closure Device ◽  
Left Atrial Appendage Closure ◽  
Novel Device ◽  
In Vitro Assessment

Background. Left atrial appendage (LAA) occlusion has been established as an alternative to systemic anticoagulation for stroke prevention in patients with atrial fibrillation; however, limitations of current devices have slowed adoption. We present preclinical evaluations of a novel device, the Conformal Left Atrial Appendage Seal (CLAAS). Methods. An in vitro assessment of conformability was conducted to evaluate the two CLAAS devices (regular 27 mm and large 35 mm) and a Watchman 2.5 (27 mm). Devices were placed within silicone tubes and compressed in a vise submerged in a water bath at 37°C. Changes in device diameter and visual seal were noted. Acute ( n = 1 ) and chronic 60-day ( n = 6 ) canine studies with gross and histologic assessment were performed. Results. Conformability bench tests demonstrated that the regular CLAAS implant was able to seal oval orifices from 20 × 30   mm to 15 × 33   mm and the large from 30 × 35   mm to 20 × 40   mm . As the CLAAS implant was compressed in the minor diameter, it increased in the major diameter, thereby filling the oval space, whereas the Watchman 2.5 showed gaps and maintained its round configuration when compressed in one direction. Seven devices were successfully implanted in the canine model with complete seal without thrombus. Histologic examination showed complete neointima covering with minimal inflammation at 60 days. Conclusions. Preclinical testing demonstrated the conformability of the CLAAS implant and its ability to seal the LAA. Clinical studies are ongoing to characterize the utility of the CLAAS implant in the treatment of patients with atrial fibrillation.

Sign in / Sign up

Export Citation Format

Share Document