scholarly journals Verapamil‐containing silicone gel reduces scar hypertrophy

2021 ◽  
Author(s):  
Jangyoun Choi ◽  
Yu Na Han ◽  
Eun Young Rha ◽  
Hwi Ju Kang ◽  
Ki Joo Kim ◽  
...  
Keyword(s):  
Silicone Gel ◽  
Scar Hypertrophy

R400 – Effects of Silicone Gel Sheeting on Scar Formation

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P177-P177
Author(s):  
Shervin Aminpour ◽  
Travis T Tollefson
Keyword(s):  
Histological Analysis ◽  
Normal Skin ◽  
Rabbit Model ◽  
Study Groups ◽  
Scar Formation ◽  
Hypertrophic Scarring ◽  
Silicone Gel ◽  
Facial Plastic ◽  
Silicone Gel Sheeting ◽  
Scar Hypertrophy

Problem The treatment of keloids and hypertrophic scars has long been a concern for facial plastic surgeons. There are a wide variety of over-the-counter products that claim to improve hypertrophic scarring. Post-surgical patients often inquire as to which of these products will give the best cosmetic result. Silicone gel sheeting is reported to provide positive outcomes with respect to a reduction in scar hypertrophy and an improvement in color differences. The exact mechanism is unknown. Micropore (3M) tape, a cheaper and more readily available product, has also been reported to reduce scar hypertrophy. This study will evaluate the differences and effectiveness of silicone gel sheeting and micropore tape in the reduction of scar hypertrophy in an animal model of scarring. Methods Hypertrophic scar formation was induced in an established rabbit model that parallels human skin. Treatment of the animals' scars was divided into 3 study groups: silicone gel sheeting, micropore tape, or no treatment. 80 total scars were treated for 30 days after the complete reepithelialization of the created scars. Both photometric and histologic analysis was performed on the scars. Scar hypertrophy was analyzed with blinded observers using a visual analog scale. Histological analysis was performed using the Scar Elevation Index, a ratio of the scar height over normal skin. Results Both photographic and histological analysis showed there was a statistically significant improvement (p<0.05) in scar hypertrophy after use of either silicone gel sheeting and micropore tape when compared with controls. Conclusion Silicone Gel Sheeting and Micropore Tape are equally effective in the reduction of hypertrophic scarring. Significance Facial plastic surgeons should consider covering facial incisions with micropore tape for 30 days after surgery to minimize the risk of hypertrophic scarring.

Successful Treatment of Nonhealing Scalp Wounds Using a Silicone Gel

2014 ◽  
Vol 40 (1) ◽  
pp. 76-79 ◽  
Author(s):  
Edward C. Monk ◽  
Ernest A. Benedetto ◽  
Anthony V. Benedetto
Keyword(s):  
Successful Treatment ◽  
Silicone Gel

Characterisation of Electrical-Thermal-Mechanical Deformation of Bonding Wires Under Silicone Gel Using LF-OCT

2021 ◽  
pp. 1-1
Author(s):  
Zhiyi Zhao ◽  
Zijian Zhang ◽  
Samuel Lawman ◽  
Zhihao Yin ◽  
Yihua Hu ◽  
...  
Keyword(s):  
Mechanical Deformation ◽  
Silicone Gel ◽  
Bonding Wires

scholarly journals 162 An Examination of Scar Modelling and Assessment Methods for the Evaluation of Scar Treatments

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
R Mistry
Keyword(s):  
Assessment Tools ◽  
Randomised Control Trial ◽  
Silicone Gel ◽  
Scar Assessment ◽  
Significant Difference ◽  
Gel Treatment ◽  
Current Assessment ◽  
Set Up ◽  
Silicone Gel Sheeting

Abstract Introduction Scarring is the final common pathway for healing within the skin. Scars can be itchy, painful, tight, and disfiguring. Despite advances in surgery there is currently no reliably effective treatment for reducing or preventing scarring. The primary aim of this research is to assess the currently available models for scarring and evaluate/further develop the utility of current assessment tools, in an effort to design a pilot randomised control trial (RCT) for silicone gel treatment of scars. Method A systematic review of scar models in humans and animals. Examination of currently used subjective and objective scar assessment tools in a plastic surgery scar clinic. A retrospective cohort study assessing long-term scar outcomes in paediatric burn patients. Results Limitations and drawbacks of many existing methods to assess scar treatments were found. No statistically significant difference in long-term scarring outcomes was found between paediatric burns patients treated surgically versus conservatively. A RCT for silicone gel sheeting in the treatment of scars was set up and successful in recruitment. Conclusions Here, we have demonstrated difficulties in establishing a scientific scar treatment model; and created a pilot study that will help to provide high-quality evidence for the efficacy of silicone gel sheeting as a treatment for scars.

scholarly journals New Evaluation Procedure for Multi-Dimensional Mechanical Strains and Tangent Moduli of Breast Implants: IDEAL IMPLANT® Structured Breast Implant Compared to Silicone Gel Implants

2019 ◽  
Vol 6 (2) ◽  
pp. 43 ◽  
Author(s):  
Harold J. Brandon ◽  
Larry S. Nichter ◽  
Dwight D. Back
Keyword(s):  
Breast Implant ◽  
Capsular Contracture ◽  
Compressive Load ◽  
Evaluation Procedure ◽  
Shape Stability ◽  
Silicone Gel ◽  
Tangent Moduli ◽  
Compressive Loads ◽  
Cohesive Gel ◽  
The Ideal

The IDEAL IMPLANT® Structured Breast Implant is a dual lumen saline-filled implant with capsular contracture and deflation/rupture rates much lower than single-lumen silicone gel-filled implants. To better understand the implant’s mechanical properties and to provide a potential explanation for these eight-year clinical results, a novel approach to compressive load testing was employed. Multi-dimensional strains and tangent moduli, metrics describing the shape stability of the total implant, were derived from the experimental load and platen spacing data. The IDEAL IMPLANT was found to have projection, diametric, and areal strains that were generally less than silicone gel implants, and tangent moduli that were generally greater than silicone gel implants. Despite having a relatively inviscid saline fill, the IDEAL IMPLANT was found to be more shape stable compared to gel implants, which implies potentially less interaction with the capsule wall when the implant is subjected to compressive loads. Under compressive loads, the shape stability of a higher cross-link density, cohesive gel implant was unexpectedly found to be similar to or the same as a gel implant. In localized diametric compression testing, the IDEAL IMPLANT was found to have a palpability similar to a gel implant, but softer than a cohesive gel implant.

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