scholarly journals A virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A provides protection against viral challenge without priming for enhanced disease in cotton rats

2013 ◽  
Vol 7 (6) ◽  
pp. 1227-1236 ◽  
Author(s):  
Tobias Kamphuis ◽  
Toon Stegmann ◽  
Tjarko Meijerhof ◽  
Jan Wilschut ◽  
Aalzen de Haan
Keyword(s):  
Respiratory Syncytial Virus ◽  
Virus Vaccine ◽  
Lipid A ◽  
Viral Challenge ◽  
Monophosphoryl Lipid A ◽  
Monophosphoryl Lipid ◽  
Cotton Rats ◽  
Syncytial Virus ◽  
Respiratory Syncytial Virus Vaccine

Monophosphoryl lipid A adjuvant reverses a principal histologic parameter of formalin-inactivated respiratory syncytial virus vaccine-induced disease

Vaccine ◽  
2001 ◽  
Vol 19 (15-16) ◽  
pp. 2048-2054 ◽  
Author(s):  
Gregory A. Prince ◽  
Françoise Denamur ◽  
Marguerite Deschamps ◽  
Nathalie Garçon ◽  
Jean-Paul Prieels ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Virus Vaccine ◽  
Lipid A ◽  
Monophosphoryl Lipid A ◽  
Monophosphoryl Lipid ◽  
Syncytial Virus ◽  
Respiratory Syncytial Virus Vaccine

The TLR4 agonist, monophosphoryl lipid A, attenuates the cytokine storm associated with respiratory syncytial virus vaccine-enhanced disease

Vaccine ◽  
2006 ◽  
Vol 24 (23) ◽  
pp. 5027-5035 ◽  
Author(s):  
Marina S. Boukhvalova ◽  
Gregory A. Prince ◽  
Layla Soroush ◽  
Dolores C. Harrigan ◽  
Stefanie N. Vogel ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Virus Vaccine ◽  
Lipid A ◽  
Cytokine Storm ◽  
Monophosphoryl Lipid A ◽  
Monophosphoryl Lipid ◽  
Tlr4 Agonist ◽  
Syncytial Virus ◽  
Respiratory Syncytial Virus Vaccine

Enhanced pulmonary pathology associated with the use of formalin-inactivated respiratory syncytial virus vaccine in cotton rats is not a unique viral phenomenon

Vaccine ◽  
1993 ◽  
Vol 11 (14) ◽  
pp. 1415-1423 ◽  
Author(s):  
Pedro A. Piedra ◽  
Philip R. Wyde ◽  
William L. Castleman ◽  
Mark W. Ambrose ◽  
Alan M. Jewell ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Virus Vaccine ◽  
Cotton Rats ◽  
Pulmonary Pathology ◽  
Syncytial Virus ◽  
Respiratory Syncytial Virus Vaccine

scholarly journals A recombinant anchorless respiratory syncytial virus (RSV) fusion (F) protein/monophosphoryl lipid A (MPL) vaccine protects against RSV-induced replication and lung pathology

Vaccine ◽  
2014 ◽  
Vol 32 (13) ◽  
pp. 1495-1500 ◽  
Author(s):  
Jorge C.G. Blanco ◽  
Marina S. Boukhvalova ◽  
Lioubov M. Pletneva ◽  
Kari Ann Shirey ◽  
Stefanie N. Vogel
Keyword(s):  
Respiratory Syncytial Virus ◽  
Lipid A ◽  
Lung Pathology ◽  
F Protein ◽  
Monophosphoryl Lipid A ◽  
Monophosphoryl Lipid ◽  
Syncytial Virus
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