Unusual stroke mimic: a rare case of Escherichia coli meningitis

2021 ◽  
Vol 51 (11) ◽  
pp. 1969-1970
Author(s):  
Julia Lim ◽  
Callum Maggs ◽  
Eugene Athan
Keyword(s):  
Escherichia Coli ◽  
Rare Case ◽  
Stroke Mimic

scholarly journals A Rare Case of Peritoneal Dialysis-Associated Peritonitis withSphingomonas koreensis

2016 ◽  
Vol 36 (2) ◽  
pp. 224-225 ◽  
Author(s):  
Julia Wallner ◽  
Reno Frei ◽  
Felix Burkhalter
Keyword(s):  
Escherichia Coli ◽  
Drinking Water ◽  
Peritoneal Dialysis ◽  
Rare Case ◽  
Aerobic Bacteria ◽  
Aquatic Environments ◽  
Gram Negative ◽  
Human Infections

Sphingomonas species are ubiquitous gram-negative, aerobic bacteria frequently found in aquatic environments such as drinking water and very seldom in hemodialysis fluids or supposedly sterile drug solutions. Human infections with the gram-negative Sphingomonas species are rare and peritonitis with these organisms even rarer. Here we report a case of polymicrobial peritonitis due to Sphingomonas koreensis and Escherichia coli in a patient undergoing peritoneal dialysis (PD).

scholarly journals Sulfation and amidinohydrolysis in the biosynthesis of giant linear polyenes

2017 ◽  
Vol 13 ◽  
pp. 2408-2415 ◽  
Author(s):  
Hui Hong ◽  
Markiyan Samborskyy ◽  
Katsiaryna Usachova ◽  
Katharina Schnatz ◽  
Peter F Leadlay
Keyword(s):  
Escherichia Coli ◽  
Gene Cluster ◽  
Late Stage ◽  
Rare Case ◽  
Gene Clusters ◽  
Biosynthetic Gene ◽  
Starter Unit ◽  
Linear Polyenes ◽  
Streptomyces Malaysiensis

Clethramycin from Streptomyces malaysiensis DSM4137, and mediomycins (produced together with clethramycin from Streptomyces mediocidicus), are near-identical giant linear polyenes apparently constructed from, respectively, a 4-guanidinobutanoate or 4-aminobutanoate starter unit and 27 polyketide extender units, and bearing a specific O-sulfonate modification at the C-29 hydroxy group. We show here that mediomycins are actually biosynthesised not by use of a different starter unit but by direct late-stage deamidination of (desulfo)clethramycin. A gene (slf) encoding a candidate sulfotransferase has been located in both gene clusters. Deletion of this gene in DSM4137 led to accumulation of desulfoclethramycin only, instead of a mixture of desulfoclethramycin and clethramycin. The mediomycin gene cluster does not encode an amidinohydrolase, but when three candidate amidinohydrolase genes from elsewhere in the S. mediocidicus genome were individually expressed in Escherichia coli and assayed, only one of them (medi4948), located 670 kbp away from the mediomycin gene cluster on the chromosome, catalysed the removal of the amidino group from desulfoclethramycin. Subsequent cloning of medi4948 into DSM4137 caused mediomycins A and B to accumulate at the expense of clethramycin and desulfoclethramycin, respectively, a rare case where an essential biosynthetic gene is not co-located with other pathway genes. Clearly, both desulfoclethramycin and clethramycin are substrates for this amidinohydrolase. Also, purified recombinant sulfotransferase from DSM4137, in the presence of 3'-phosphoadenosine-5'-phosphosulfate as donor, efficiently converted mediomycin B to mediomycin A in vitro. Thus, in the final steps of mediomycin A biosynthesis deamidination and sulfotransfer can take place in either order.

scholarly journals Identification of Clostridium septicum in a tubo-ovarian abscess: A rare case and review of the literature

2014 ◽  
Vol 71 (9) ◽  
pp. 884-888 ◽  
Author(s):  
Ali Yavuzcan ◽  
Mete Çağlar ◽  
Serdar Dilbaz ◽  
Selahattin Kumru ◽  
Fatma Avcıoğlu ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Differential Diagnosis ◽  
Rare Case ◽  
Automated System ◽  
Free Fluid ◽  
Review Of The Literature ◽  
Clostridium Septicum ◽  
E Coli ◽  
Pelvic Organs ◽  
Ovarian Abscess

Introduction. Tubo-ovarian abscess (TOA) is a conglomerated mass of pelvic organs including tube, ovary, and bowel. The most commonly isolated organisms from TOAs are Escherichia coli (E. coli) and Bacteroides species. Case Report. We reported a case of Clostridium septicum (C. septicum) infection from a ruptured TOA with atypical clinical features. Culture of intra-abdominal free fluid obtained during surgery yielded C. septicum. VITEK II (bioM?rieux, France) automated system was used for advanced identification of the bacteria. Parenteral clindamycin in combination with an aminoglycoside was used. The patient was discharged 19 days after the surgery and was clinically asymptomatic 6 months after the surgery. Conclusion. The differential diagnosis of TOA caused by C. septicum can be difficult, due to the lack of the symptoms. Tissues infected with C. septicum can become necrotic. A combination of early, adequate antibiotic therapy and surgery is the key point of the treatment.

scholarly journals Stroke Mimic: A Case of Unilateral Thyrotoxic Hypokalemic Periodic Paralysis

2020 ◽  
Vol 4 (1) ◽  
pp. 75-78 ◽  
Author(s):  
Michael Lajeunesse ◽  
Scott Young
Keyword(s):  
Skeletal Muscle ◽  
Rare Case ◽  
Periodic Paralysis ◽  
Emergency Physicians ◽  
Hypokalemic Periodic Paralysis ◽  
Muscle Paralysis ◽  
Proximal Extremity ◽  
Stroke Mimic ◽  
Ischemic Attack ◽  
Thyrotoxic Hypokalemic Periodic Paralysis

Thyrotoxic hypokalemic periodic paralysis (THPP) is a condition that results in transient skeletal muscle paralysis secondary to intracellular potassium sequestration. Susceptible individuals often have an underlying channelopathy, which may be exacerbated by lifestyle factors or underlying medical comorbidities such as hyperthyroidism or diarrheal illness. Classically, THPP presents with paralysis of proximal extremity musculature. In this case, we present a rare case of unilateral THPP. Such a presentation is relevant to emergency physicians as it mimics a stroke or transient ischemic attack and should be considered on the differential for unilateral neurologic deficits.

scholarly journals A Rare Case Study on Escherichia Coli Pneumonia

2022 ◽  
Vol 04 (12) ◽  
pp. 46-54
Author(s):  
Deepak Sewada ◽  
Shri Ram Saini ◽  
Sunil kumar
Keyword(s):  
Escherichia Coli ◽  
Rare Case

scholarly journals A Rare Case of Fournier’s Gangrene caused by Helcococcus kunzii

2016 ◽  
Vol 6 (2) ◽  
pp. 43-46
Author(s):  
Mazen A. Badawi ◽  
Maha M. Al-Alawi
Keyword(s):  
Risk Factors ◽  
Escherichia Coli ◽  
Rare Case ◽  
Fournier’S Gangrene ◽  
Local Infection ◽  
Fournier's Gangrene ◽  
Skin Flora ◽  
Common Risk Factors ◽  
And Staphylococcus Aureus ◽  
Positive Coccus

Fournier’s gangrene is an acute rapidly progressing form of necrotizing fasciitis involving the genitalia and perianal regions. Trauma and local infection are the most common risk factors especially in the setting of diabetes. It is usually a polymicrobial infection caused by skin flora of the genital area. The most commonly isolated aerobic microorganism are Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus, while Bacteroides fragilis is a common culprit from the anaerobic group. We report a patient with Fournier’s gangrene caused by Helcococcus kunzii; anaerobic gram-positive coccus not known to be associated with Fournier’s gangrene before.

scholarly journals Is whole genome sequencing the answer for identifying Shigella bacteraemia?

2019 ◽  
Vol 12 (12) ◽  
pp. e231596
Author(s):  
Dora Amos ◽  
Priya Khanna ◽  
Sayeed Adnan Aali ◽  
Guduru Gopal Rao
Keyword(s):  
Escherichia Coli ◽  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Rare Case ◽  
Shigella Flexneri ◽  
Genomic Sequencing ◽  
Whole Genome ◽  
Laboratory Techniques

We present a rare case of Shigella flexneri bacteraemia and the challenges of differentiating Escherichia coli and Shigella spp using conventional and newer laboratory techniques in diagnostic laboratories. The organism was identified only after whole genomic sequencing .

scholarly journals A rare case of gliomatosis cerebri lurking beneath the shadows of a stroke mimic

2021 ◽  
Vol 16 (9) ◽  
pp. 2701-2705
Author(s):  
Apoorv Prasad ◽  
Gage Hurlburt ◽  
Emily Van Antwerp ◽  
Samiksha Srivastava ◽  
Shitiz Sriwastava
Keyword(s):  
Rare Case ◽  
Gliomatosis Cerebri ◽  
Stroke Mimic
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