Adherence to medication, glycaemic control and hospital attendance in young adults with type 2 diabetes

2018 ◽  
Vol 48 (6) ◽  
pp. 728-731 ◽  
Author(s):  
Shalini Kunasegaran ◽  
Junaid Beig ◽  
Manish Khanolkar ◽  
Tim Cundy
2020 ◽  
Vol 7 (49) ◽  
pp. 2892-2897
Author(s):  
Sajith Kumar Soman ◽  
Binu Areekal ◽  
Sudhiraj Thiruthara Sukumaran ◽  
Safa Puliyakkadi ◽  
Rajesh Koothupalakkal Ravi

BACKGROUND The prevalence of type 2 diabetes mellitus (T2DM) is increasing quickly all over the world. In spite of effective treatment guidelines for type 2 diabetes, in majority of the people, the disease is poorly controlled with existing therapies. Glycaemic control is considered as the most important step for prevention of organ damage and other complications of diabetes. A study on the prevalence and determinants of poor glycaemic control can assist in understanding the expanse of this problems and the ways to address it. We wanted to study the prevalence and determinants of poor glycaemic control among adult patients with type II diabetes mellitus attending a primary health care setting. METHODS The cross-sectional study was conducted in the outpatient department of NCD clinic in a Primary health centre of Kerala for a period of six months. Two hundred and fifty individuals diagnosed with Type II DM for a year were recruited as study participants. The study participants were interviewed using a semi-structured questionnaire. Adherence to medication was assessed using The Morisky Medication Adherence Scale. Anthropometric measurements and blood pressures were recorded. HbA1c and RBS was measured using semi quantitative technique. Any patient with an HbA1c of more than 7 was defined as having poor glycaemic control. RESULTS 64.4 % of the participants had poor glycaemic control. Poor adherence to medication, fewer visits to doctor, lack of diet modification, frequent junk food consumption, higher body mass index and lack of exercise were found to be significantly associated with poor glycaemic control. CONCLUSIONS A focused approach targeting these modifiable risk factors, especially in primary care setting, has the potential to bring about better glycaemic control which can prevent and minimize the occurrence of diabetes complications. KEYWORDS Poor Glycaemic Control, Uncontrolled Diabetes, Diabetes Mellitus, HbA1c, Diabetes Complications


Author(s):  
May‐Hung Lin ◽  
Horng‐Yih Ou ◽  
Ruey‐Hsia Wang ◽  
Ching‐Han Lin ◽  
Hsiu‐Yun Liao ◽  
...  

2013 ◽  
Vol 3 (1) ◽  
pp. 11-18 ◽  
Author(s):  
Zafar Ahmed Latif ◽  
Md. Faruque Pathan ◽  
Md. Nazrul Islam Siddiqui ◽  
MA Mannan ◽  
SM Ashrafuzzaman ◽  
...  

Objective: To present results from the Bangladesh cohort of the A1chieve study receiving insulin detemir (Levemir) ± oral anti diabetic drugs. Methods: Out of 1093 patients recruited from 49 sites in Bangladesh, 370 were initiated on insulin detemir (Levemir).Study visits were defined as baseline, interim (around 12 weeks from baseline) and final (around 24 weeks from baseline) visit. Results: Glycaemic control was poor in all the groups at baseline. In the entire cohort at 24 weeks, significant reductions from baseline were observed in mean HbA1c (from 10.0 % to 7.2%, p<0.001), FPG (from 10.5 to 6.7 mmol/L, p<0.001) and PPPG (from 15.3 to 8.9 mmol/L, p<0.001) levels. Overall 45.5% of the participants achieved target HbA1c level of < 7% after 24 weeks. The rate of all hypoglycaemic events in the entire cohort reduced from 1.34 (baseline) to 0.12 events/person year after 24 weeks of insulin detemir therapy (p<0.0001). There was no clinically relevant change in body weight in insulin naïve or prior insulin users groups after 24 weeks of insulin detemir therapy. Conclusions: The current study suggests that insulin detemir may be considered as a safe and effective option for initiating insulin therapy for type 2 diabetes in Bangladesh. Birdem Med J 2013; 3(1): 11-18 DOI: http://dx.doi.org/10.3329/birdem.v3i1.17121


Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 780-P
Author(s):  
TINA PARK ◽  
MIYA Z. OSAKI ◽  
MAHAM QURESHI ◽  
ALYSSA JANG ◽  
SHIVANI AGARWAL

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 279-OR
Author(s):  
ALLISON SHAPIRO ◽  
DANA DABELEA ◽  
JEANETTE M. STAFFORD ◽  
RALPH DAGOSTINO ◽  
CATHERINE PIHOKER ◽  
...  

2011 ◽  
pp. 5-10
Author(s):  
Huu Dang Tran

The incretins are peptide hormones secreted from the gut in response to food. They increase the secretion of insulin. The incretin response is reduced in patients with type 2 diabetes so drugs acting on incretins may improve glycaemic control. Incretins are metabolised by dipeptidyl peptidase, so selectively inhibiting this enzyme increases the concentration of circulating incretins. A similar effect results from giving an incretin analogue that cannot be cleaved by dipeptidyl peptidase. Studies have identified other actions including improvement in pancreatic β cell glucose sensitivity and, in animal studies, promotion of pancreatic β cell proliferation and reduction in β cell apoptosis.


2017 ◽  
Vol 24 (4) ◽  
pp. 384-403 ◽  
Author(s):  
Demetres Leonidas ◽  
Joseph Hayes ◽  
Atsushi Kato ◽  
Vassiliki Skamnaki ◽  
Demetra Chatzileontiadou ◽  
...  

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