Editorial Comment to Effect of optimal neoadjuvant chemotherapy on oncological outcomes of locally advanced bladder cancer with laparoscopic radical cystectomy: A matched‐pair analysis in a multicenter cohort

Author(s):  
Nozomi Hayakawa ◽  
Eiji Kikuchi
Author(s):  
Vikram M. Narayan

This study summarizes a landmark study on the role of neoadjuvant chemotherapy with methotrexate, vinblastine, doxorubicin, and cisplatin (M-VAC) in patients with muscle-invasive bladder cancer. This randomized study of M-VAC plus cystectomy versus cystectomy alone suggested improved overall survival in patients receiving neoadjuvant therapy. Severe granulocytopenia was a common adverse effect in the chemotherapy group, but no deaths were attributed to chemotherapy.


2014 ◽  
Vol 13 (4) ◽  
pp. 435-441 ◽  
Author(s):  
Abdul R Hakeem ◽  
Caroline S Verbeke ◽  
Alison Cairns ◽  
Amer Aldouri ◽  
Andrew M Smith ◽  
...  

2014 ◽  
Vol 13 (5) ◽  
pp. 150
Author(s):  
B. Özdemir ◽  
B. Akdoğan ◽  
M. Altan ◽  
B. Çıtamak ◽  
O. Kahraman ◽  
...  

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