Effect of optimal neoadjuvant chemotherapy on oncological outcomes of locally advanced bladder cancer with laparoscopic radical cystectomy: A matched‐pair analysis in a multicenter cohort

2021 ◽  
Author(s):  
Masashi Kubota ◽  
Toru Kanno ◽  
Takahiro Inoue ◽  
Toshinari Yamasaki ◽  
Kazuhiro Okumura ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Radical Cystectomy ◽  
Locally Advanced ◽  
Matched Pair ◽  
Oncological Outcomes ◽  
Matched Pair Analysis ◽  
Multicenter Cohort ◽  
Advanced Bladder Cancer ◽  
Pair Analysis

Long-term evaluation of oncologic and functional outcomes after laparoscopic open-assisted radical cystectomy: a matched-pair analysis

2014 ◽  
Vol 32 (6) ◽  
pp. 1455-1461 ◽  
Author(s):  
Simone Albisinni ◽  
Ksenija Limani ◽  
Lisa Ingels ◽  
Felix Kwizera ◽  
Renaud Bollens ◽  
...  
Keyword(s):  
Radical Cystectomy ◽  
Functional Outcomes ◽  
Matched Pair ◽  
Matched Pair Analysis ◽  
Term Evaluation ◽  
Pair Analysis

Neoadjuvant Chemotherapy Plus Cystectomy Compared With Cystectomy Alone for Locally Advanced Bladder Cancer

2021 ◽  
pp. 141-146
Author(s):  
Vikram M. Narayan
Keyword(s):  
Adverse Effect ◽  
Overall Survival ◽  
Bladder Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Randomized Study ◽  
Locally Advanced ◽  
Common Adverse Effect ◽  
Advanced Bladder Cancer ◽  
Muscle Invasive

This study summarizes a landmark study on the role of neoadjuvant chemotherapy with methotrexate, vinblastine, doxorubicin, and cisplatin (M-VAC) in patients with muscle-invasive bladder cancer. This randomized study of M-VAC plus cystectomy versus cystectomy alone suggested improved overall survival in patients receiving neoadjuvant therapy. Severe granulocytopenia was a common adverse effect in the chemotherapy group, but no deaths were attributed to chemotherapy.

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