Editorial Comment to Equivalent survival and improved preservation of renal function after distal ureterectomy compared with nephroureterectomy in patients with urothelial carcinoma of the distal ureter: A propensity score-matched multicenter study

2014 ◽  
Vol 21 (11) ◽  
pp. 1105-1105
Author(s):  
Matthew A Meissner ◽  
Vitaly Margulis ◽  
Bishoy A Gayed
Keyword(s):  
Renal Function ◽  
Propensity Score ◽  
Editorial Comment ◽  
Urothelial Carcinoma ◽  
Multicenter Study ◽  
Distal Ureter ◽  
Distal Ureterectomy

772 Distal ureterectomy for urothelial carcinoma of the distal ureter: A single institutional experience

2012 ◽  
Vol 11 (1) ◽  
pp. e772-e772a
Author(s):  
O. Dalpiaz ◽  
G. Ehrlich ◽  
G. Gallé ◽  
K. Pummer ◽  
R. Zigeuner
Keyword(s):  
Urothelial Carcinoma ◽  
Distal Ureter ◽  
Institutional Experience ◽  
Distal Ureterectomy

Distal ureterectomy is a safe surgical option in patients with urothelial carcinoma of the distal ureter

2014 ◽  
Vol 32 (1) ◽  
pp. 34.e1-34.e8 ◽  
Author(s):  
Orietta Dalpiaz ◽  
Georg Ehrlich ◽  
Franz Quehenberger ◽  
Karl Pummer ◽  
Richard Zigeuner
Keyword(s):  
Urothelial Carcinoma ◽  
Distal Ureter ◽  
Surgical Option ◽  
Distal Ureterectomy

scholarly journals Treatment of Distal Upper Tract Urothelial Cancer with Distal Ureterectomy Preserves Renal Function without Increasing Local Recurrence Rate Compared with Radical Nephroureterectomy

2021 ◽  
Vol 5 (1) ◽  
pp. 86-90
Author(s):  
Mahesh Bahadur Adhikari ◽  
Woon Chau Tsang ◽  
Ho Yee Tiong
Keyword(s):  
Renal Function ◽  
Hospital Stay ◽  
Urothelial Carcinoma ◽  
Urothelial Cancer ◽  
Upper Tract Urothelial Carcinoma ◽  
Radical Nephroureterectomy ◽  
Upper Tract ◽  
Duration Of Surgery ◽  
Upper Tract Urothelial Cancer ◽  
Distal Ureterectomy

Introduction: Kidney sparing surgery like endoscopic resection and distal ureterectomy has been recently proposed as alternative surgical options to manage distal Upper Tract Urothelial Cancer. This study aims to compare the surgical, oncological and functional outcomes of distal ureterectomy and Radical Nephroureterectomy for distal Upper Tract Urothelial Carcinoma.  Methods and Material: Out of 57 patients with Upper Tract Urothelial Carcinoma treated surgically at a single institution between 2010 and 2016, nineteen patients had distal Upper Tract Urothelial Carcinoma. A retrospective review was performed on these 19 patients (11 Radical Nephroureterectomy and 8 distal ureterectomy). Radical Nephroureterectomy was performed using an open or laparoscopic approach (n= 4 and 7 respectively). All Distal Ureterectomy patients were performed via an open extra-peritoneal Gibson incision. Pelvic lymphadenectomy and Subsequent ureteroneocystostomy in the Distal Ureterectomy group was performed directly and was augmented by psoas hitch or using boari flap reconstruction. Demographic, clinical features and post-operative outcomes were compared between the Radical Nephroureterectomy and Distal Ureterectomy groups.  Results: There was a trend towards shorter mean duration of surgery (238±34 vs. 286 ±90 min) and length of hospital stay (LOS) (7.6±2.8 vs. 17.3±20.7 days) in the Distal Ureterectomy group compared to the Radical Nephroureterectomy group (P=NS). Peri-operative Complication of Clavien grade 1-2 was seen in 4(33.33%) Radical Nephroureterectomy and 3 (37.5%) Distal Ureterectomy cases respectively. All patients had high grade Upper Tract Urothelial Carcinoma with equivalent pTNM staging in both groups with clear surgical margins. Immediate post-operative renal function improvement was statistically significant in the Distal Ureterectomy group (Radical Nephroureterectomy 2.27±5.93 vs 10.86±9.92 Distal Ureterectomy, p=0.034). Three out of 11 Radical Nephroureterectomy group patients required dialysis.  Conclusions: Local recurrences were similar after Distal Ureterectomy and Radical Nephroureterectomy with equivalent pathological outcomes in distal Upper Tract Urothelial Carcinoma. There was a clear trend towards shorter hospital stay and better renal function preservation in favor of Distal Ureterectomy with fewer patients requiring dialysis. 

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