Equivalent survival and improved preservation of renal function after distal ureterectomy compared with nephroureterectomy in patients with urothelial carcinoma of the distal ureter: A propensity score-matched multicenter study

2014 ◽  
Vol 21 (11) ◽  
pp. 1098-1104 ◽  
Author(s):  
Hiroshi Fukushima ◽  
Kazutaka Saito ◽  
Junichiro Ishioka ◽  
Yoh Matsuoka ◽  
Noboru Numao ◽  
...  
Keyword(s):  
Renal Function ◽  
Propensity Score ◽  
Urothelial Carcinoma ◽  
Multicenter Study ◽  
Distal Ureter ◽  
Distal Ureterectomy

772 Distal ureterectomy for urothelial carcinoma of the distal ureter: A single institutional experience

2012 ◽  
Vol 11 (1) ◽  
pp. e772-e772a
Author(s):  
O. Dalpiaz ◽  
G. Ehrlich ◽  
G. Gallé ◽  
K. Pummer ◽  
R. Zigeuner
Keyword(s):  
Urothelial Carcinoma ◽  
Distal Ureter ◽  
Institutional Experience ◽  
Distal Ureterectomy

Distal ureterectomy is a safe surgical option in patients with urothelial carcinoma of the distal ureter

2014 ◽  
Vol 32 (1) ◽  
pp. 34.e1-34.e8 ◽  
Author(s):  
Orietta Dalpiaz ◽  
Georg Ehrlich ◽  
Franz Quehenberger ◽  
Karl Pummer ◽  
Richard Zigeuner
Keyword(s):  
Urothelial Carcinoma ◽  
Distal Ureter ◽  
Surgical Option ◽  
Distal Ureterectomy

scholarly journals Treatment of Distal Upper Tract Urothelial Cancer with Distal Ureterectomy Preserves Renal Function without Increasing Local Recurrence Rate Compared with Radical Nephroureterectomy

2021 ◽  
Vol 5 (1) ◽  
pp. 86-90
Author(s):  
Mahesh Bahadur Adhikari ◽  
Woon Chau Tsang ◽  
Ho Yee Tiong
Keyword(s):  
Renal Function ◽  
Hospital Stay ◽  
Urothelial Carcinoma ◽  
Urothelial Cancer ◽  
Upper Tract Urothelial Carcinoma ◽  
Radical Nephroureterectomy ◽  
Upper Tract ◽  
Duration Of Surgery ◽  
Upper Tract Urothelial Cancer ◽  
Distal Ureterectomy

Introduction: Kidney sparing surgery like endoscopic resection and distal ureterectomy has been recently proposed as alternative surgical options to manage distal Upper Tract Urothelial Cancer. This study aims to compare the surgical, oncological and functional outcomes of distal ureterectomy and Radical Nephroureterectomy for distal Upper Tract Urothelial Carcinoma.  Methods and Material: Out of 57 patients with Upper Tract Urothelial Carcinoma treated surgically at a single institution between 2010 and 2016, nineteen patients had distal Upper Tract Urothelial Carcinoma. A retrospective review was performed on these 19 patients (11 Radical Nephroureterectomy and 8 distal ureterectomy). Radical Nephroureterectomy was performed using an open or laparoscopic approach (n= 4 and 7 respectively). All Distal Ureterectomy patients were performed via an open extra-peritoneal Gibson incision. Pelvic lymphadenectomy and Subsequent ureteroneocystostomy in the Distal Ureterectomy group was performed directly and was augmented by psoas hitch or using boari flap reconstruction. Demographic, clinical features and post-operative outcomes were compared between the Radical Nephroureterectomy and Distal Ureterectomy groups.  Results: There was a trend towards shorter mean duration of surgery (238±34 vs. 286 ±90 min) and length of hospital stay (LOS) (7.6±2.8 vs. 17.3±20.7 days) in the Distal Ureterectomy group compared to the Radical Nephroureterectomy group (P=NS). Peri-operative Complication of Clavien grade 1-2 was seen in 4(33.33%) Radical Nephroureterectomy and 3 (37.5%) Distal Ureterectomy cases respectively. All patients had high grade Upper Tract Urothelial Carcinoma with equivalent pTNM staging in both groups with clear surgical margins. Immediate post-operative renal function improvement was statistically significant in the Distal Ureterectomy group (Radical Nephroureterectomy 2.27±5.93 vs 10.86±9.92 Distal Ureterectomy, p=0.034). Three out of 11 Radical Nephroureterectomy group patients required dialysis.  Conclusions: Local recurrences were similar after Distal Ureterectomy and Radical Nephroureterectomy with equivalent pathological outcomes in distal Upper Tract Urothelial Carcinoma. There was a clear trend towards shorter hospital stay and better renal function preservation in favor of Distal Ureterectomy with fewer patients requiring dialysis. 

scholarly journals Improvement of renal function after transcatheter aortic valve replacement and its impact on survival

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Dominik Kylies ◽  
Sandra Freitag-Wolf ◽  
Florian Fulisch ◽  
Hatim Seoudy ◽  
Christian Kuhn ◽  
...  
Keyword(s):  
Renal Function ◽  
Aortic Valve ◽  
Propensity Score ◽  
Aortic Valve Replacement ◽  
Survival Time ◽  
Valve Replacement ◽  
Transcatheter Aortic Valve Replacement ◽  
Nyha Class ◽  
Transcatheter Aortic Valve ◽  
Significant Survival

Abstract Background Chronic kidney disease as well as acute kidney injury are associated with adverse outcomes after transcatheter aortic valve replacement (TAVR). However, little is known about the prognostic implications of an improvement in renal function after TAVR. Methods Renal improvement (RI) was defined as a decrease in postprocedural creatinine in μmol/l of ≥1% compared to its preprocedural baseline value. A propensity score representing the likelihood of RI was calculated to define patient groups which were comparable regarding potential confounders (age, sex, BMI, NYHA classification, STS score, log. EuroSCORE, history of atrial fibrillation/atrial flutter, pulmonary disease, previous stroke, CRP, creatinine, hsTNT and NT-proBNP). The cohort was stratified into 5 quintiles according to this propensity score and the survival time after TAVR was compared within each subgroup. Results Patients in quintile 5 (n = 93) had the highest likelihood for RI. They were characterized by higher creatinine, lower eGFR, higher NYHA class, higher NT-proBNP, being mostly female and having shorter overall survival time. Within quintile 5, patients without RI had significantly shorter survival compared to patients with RI (p = 0.002, HR = 0.32, 95% CI = [0.15–0.69]). There was no survival time difference between patients with and without RI in the whole cohort (p = 0.12) and in quintiles 1 to 4 (all p > 0.16). Analyses of specific subgroups showed that among patients with NYHA class IV, those with RI also had a significant survival time benefit (p < 0.001, HR = 0.15; 95%-CI = [0.05–0.44]) compared to patients without RI. Conclusions We here describe a propensity score-derived specific subgroup of patients in which RI after TAVR correlated with a significant survival benefit.

Preoperative predictors of renal function decline after radical nephroureterectomy for upper tract urothelial carcinoma

2014 ◽  
Vol 114 (5) ◽  
pp. 674-679 ◽  
Author(s):  
Matthew Kaag ◽  
Landon Trost ◽  
R. Houston Thompson ◽  
Ricardo Favaretto ◽  
Vanessa Elliott ◽  
...  
Keyword(s):  
Renal Function ◽  
Urothelial Carcinoma ◽  
Upper Tract Urothelial Carcinoma ◽  
Radical Nephroureterectomy ◽  
Renal Function Decline ◽  
Upper Tract ◽  
Preoperative Predictors

Effect of Sex on Prognosis of Urothelial Carcinoma: Propensity Score Matching Analysis

2015 ◽  
Vol 13 (2) ◽  
pp. e113-e121 ◽  
Author(s):  
Min Soo Choo ◽  
Chang Wook Jeong ◽  
Cheol Kwak ◽  
Hyeon Hoe Kim ◽  
Ja Hyeon Ku
Keyword(s):  
Propensity Score ◽  
Urothelial Carcinoma ◽  
Propensity Score Matching ◽  
Propensity Score Matching Analysis
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