Poor maternal anthropometric status before conception is associated with a deleterious infant growth during the first year of life: a longitudinal preconceptional cohort

2019 ◽  
Vol 15 (1) ◽  
Author(s):  
Gino Agbota ◽  
Nadine Fievet ◽  
Barbara Heude ◽  
Manfred Accrombessi ◽  
Urbain Ahouayito ◽  
...  
Keyword(s):  
Infant Growth ◽  
First Year ◽  
First Year Of Life ◽  
Anthropometric Status

scholarly journals Leptin levels at birth and infant growth: the EPOCH study

2014 ◽  
Vol 5 (3) ◽  
pp. 214-218 ◽  
Author(s):  
J. L. Kaar ◽  
J. T. Brinton ◽  
T. Crume ◽  
R. F. Hamman ◽  
D. H. Glueck ◽  
...  
Keyword(s):  
Cord Blood ◽  
Perinatal Outcomes ◽  
Epidemiological Studies ◽  
In Utero ◽  
Feedback Mechanism ◽  
Infant Growth ◽  
Sufficient Evidence ◽  
First Year ◽  
First Year Of Life ◽  
Maternal Overweight

Objective: To examine the association of cord blood leptin with body mass index (BMI) growth velocity from birth to 12 months of age among infants exposed and not exposed to over-nutrition in utero (defined as maternal overweight/obesity or presence of gestational diabetes). Methods: 185 infants enrolled in the Exploring Perinatal Outcomes among Children study (76 exposed and 109 not exposed) had leptin and insulin measured in cord blood. Longitudinal weight and length measures in the first 12 months of life (average 4 per participant) obtained from medical records were used to compute BMI growth rates. Mixed models were used to examine associations of cord blood leptin with growth. Results: Compared with unexposed infants, those exposed had significantly higher cord blood insulin (8.64 v. 6.97 uU/ml, P<0.01) and leptin levels (8.89 v. 5.92 ng/ml, P=0.05) as well as increased birth weights (3438.04 v. 3306.89 g, P=0.04). There was an inverse relationship between cord leptin levels and BMI growth from birth to 12 months of age (P=0.005); however, exposure to over-nutrition in utero did not significantly modify this association (P=0.59). Conclusion: We provide support of a possible operational feedback mechanism by which lower cord blood leptin levels are associated with faster infant growth in the first year of life. Our data do not tend to support the hypothesis that this mechanism is altered in infants exposed to over-nutrition in utero; however our sample is too small to provide sufficient evidence. Larger epidemiological studies are needed to elucidate the mechanisms responsible for increased propensity for obesity in exposed offspring.

Infant Growth During the First Year of Life and Subsequent Hospitalization to 8 Years of Age

Epidemiology ◽  
2010 ◽  
Vol 21 (3) ◽  
pp. 332-339 ◽  
Author(s):  
L. L. Hui ◽  
C. Mary Schooling ◽  
M. Y. Wong ◽  
L. M. Ho ◽  
T. H. Lam ◽  
...  
Keyword(s):  
Infant Growth ◽  
First Year ◽  
First Year Of Life

scholarly journals Association of antioxidant vitamins and oxidative stress levels in pregnancy with infant growth during the first year of life

2008 ◽  
Vol 11 (10) ◽  
pp. 998-1005 ◽  
Author(s):  
Juhee Hong ◽  
Eun Ae Park ◽  
Young-Ju Kim ◽  
Hwa Young Lee ◽  
Bo-Hyun Park ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cohort Study ◽  
Vitamin C ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Infant Growth ◽  
First Year ◽  
First Year Of Life ◽  
And Oxidative Stress ◽  
In Pregnancy

AbstractObjectiveWhereas there are numerous reports in the literature relating the impact of maternal nutritional status on subsequent birth outcome, much less is known about the long-term impact on infant growth after birth. Therefore, we conducted a prospective cohort study to investigate the association of maternal micronutrient status (vitamins A, C and E, folate) and oxidative stress status in pregnancy with infant growth during the first year of life.DesignProspective cohort study.SettingOutpatient clinic of obstetrics, Ewha Womans University Hospital, Seoul, South Korea.Subjects and methodsTwo groups were constructed for this study – the Ewha pregnancy cohort (n = 677) and the infant growth cohort comprising follow-up live newborns of all the recruited pregnant women (n = 317). Maternal serum vitamin and urinary oxidative stress levels were collected and infant weights and heights were measured at birth and at 6 and 12 months after birth.ResultsDivision of the subjects into folate-deficient and normal groups revealed that infant weight and height at 0, 6 and 12 months were adversely affected by folate deficiency. High maternal vitamin C was associated with increased infant weight and height at birth and after birth.ConclusionOur findings indicate the importance of preventing folate deficiency and supplementing vitamin C during pregnancy.

scholarly journals Maternal Diet Quality and Infant Growth Trajectories During the First Year of Life (OR35-07-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Andrea Lopez-Cepero ◽  
Lisa Nobel ◽  
Tiffany Moore-Simas ◽  
Milagros Rosal
Keyword(s):  
Diet Quality ◽  
Rapid Growth ◽  
Maternal Diet ◽  
Infant Growth ◽  
Growth Trajectory ◽  
Growth Trajectories ◽  
First Year ◽  
Lower Odds ◽  
Trajectory Models ◽  
First Year Of Life

Abstract Objectives To examine the association between maternal diet quality and infant weight for length growth trajectory during their first year of life. Methods Participants were singleton infant-mother pairs (N = 77) enrolled in the Pregnancy and Postpartum Observational Dietary Study. Mothers completed socio-demographics and dietary (24-hour recalls) assessments at 3 months postpartum. The Alternate Healthy Eating Index (aHEI) was calculated to measure maternal diet quality. Infant weight for length measures from birth to 12 months were abstracted from pediatric records. World Health Organization guidelines were used to calculate infants’ weight for length percentiles. Group-based trajectory analysis was done to identify subgroups of infants with similar growth profiles and to evaluate the association between maternal aHEI and infant's growth trajectory. Models were adjusted for maternal age, race, education and excessive gestational weight gain (GWG). Results Mothers’ mean age was 28 years ± 5.2; 27% were Latina, and 55% had some college education or more; 60% had experienced excessive GWG; and their average aHEI was 26.7 ± 7.5. Three infant growth trajectories were identified: a low and stable growth group (43.2%), a rapid growth group (33.5%), and a moderate growth group (23.3%). Maternal aHEI was significantly associated with lower odds of having their infant in the rapid growth group (OR = 0.83; P = 0.012), with each unit increase in aHEI score being associated with 17% lower odds of infant's rapid growth. Conclusions Trajectory models suggested three patterns of infant growth. Higher maternal diet quality was associated with lower odds of infant rapid growth. Future studies are needed to replicate these findings in larger cohorts and identify mediators of this association to prevent childhood obesity. Funding Sources CCTS (UL1TR001453), NCATS (UL1TR000161), NIMHD (1P60MD006912-02), CDC (U48-DP001933), NIGMS (R25GM113686-02), NHLBI (F30HL128012), and Canadian Institutes of Health Research (DFS-140394).

scholarly journals INFANT GROWTH DURING THE FIRST YEAR OF LIFE

2015 ◽  
Vol 25 (2) ◽  
pp. 211
Author(s):  
Priscila Vitor Alves Ferreira ◽  
Viviane Santos Leal ◽  
Marcella Moura Câmara da Silva ◽  
Adriana De Oliveira Mukai ◽  
Celso Luiz de Sá Rodrigues ◽  
...  
Keyword(s):  
Infant Growth ◽  
First Year ◽  
First Year Of Life

Infant Growth and the Occurrence of Developmental Defects of Enamel in 12-Year-Olds

2015 ◽  
Vol 49 (6) ◽  
pp. 575-582 ◽  
Author(s):  
Hai Ming Wong ◽  
Si-Min Peng ◽  
Nigel M. King ◽  
Colman McGrath
Keyword(s):  
Birth Weight ◽  
Rapid Growth ◽  
Critical Period ◽  
Parental Education ◽  
Infant Growth ◽  
Permanent Dentition ◽  
First Year ◽  
Developmental Defects ◽  
First Year Of Life ◽  
Developmental Defects Of Enamel

Background/Aims: To investigate the association between birth weight and infant growth during the first year of life and the occurrence of developmental defects of enamel (DDE) in permanent dentition. Methods: A random sample of 668 12-year-old students was recruited from a birth cohort. Permanent incisors and first molars were clinically examined for DDE using the modified FDI (DDE) index. Multivariable negative binomial regression was used to examine the association of growth trajectory (five categories) from birth to 12 months with the occurrence of DDE (any defects, demarcated opacities, diffuse opacities, and hypoplasia) in the permanent dentition. Results: The response rate was 76.9% (n = 514). Four hundred and eighty-five children had complete records of growth- and health-related data. In the unadjusted model, infants who had birth weights closer to the WHO average and rapid growth were more likely to have ‘demarcated opacities' (p < 0.05), and the first 3 months of life was the ‘critical period' to develop ‘demarcated opacities' in permanent dentition. However, after adjusting for the confounders (gender, gestational age, mode of delivery, type of feeding, parental education, and health status), significant association with the occurrence of ‘demarcated opacities' (p < 0.05) remained only for the children of trajectory V (heavier birth weights and rapid growth); no ‘critical period' was found to be significantly associated with DDE. Conclusions: Infants with heavy birth weight and rapid growth during the first year of life were more vulnerable to the occurrence of DDE in terms of demarcated opacities in their permanent dentition.

The Development of Swallowing Respiratory Coordination

2009 ◽  
Vol 18 (1) ◽  
pp. 19-24
Author(s):  
Maggie-Lee Huckabee
Keyword(s):  
Cortical Activation ◽  
First Year ◽  
Healthy Children ◽  
Nasal Airflow ◽  
Single Session ◽  
Primary Finding ◽  
Patterns Of Behavior ◽  
Cortical Modulation ◽  
First Year Of Life ◽  
Swallowing Apnea

Abstract Research exists that evaluates the mechanics of swallowing respiratory coordination in healthy children and adults as well and individuals with swallowing impairment. The research program summarized in this article represents a systematic examination of swallowing respiratory coordination across the lifespan as a means of behaviorally investigating mechanisms of cortical modulation. Using time-locked recordings of submental surface electromyography, nasal airflow, and thyroid acoustics, three conditions of swallowing were evaluated in 20 adults in a single session and 10 infants in 10 sessions across the first year of life. The three swallowing conditions were selected to represent a continuum of volitional through nonvolitional swallowing control on the basis of a decreasing level of cortical activation. Our primary finding is that, across the lifespan, brainstem control strongly dictates the duration of swallowing apnea and is heavily involved in organizing the integration of swallowing and respiration, even in very early infancy. However, there is evidence that cortical modulation increases across the first 12 months of life to approximate more adult-like patterns of behavior. This modulation influences primarily conditions of volitional swallowing; sleep and naïve swallows appear to not be easily adapted by cortical regulation. Thus, it is attention, not arousal that engages cortical mechanisms.

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