Parental and child genetic contributions to obesity traits in early life based on 83 loci validated in adults: the FAMILY study

2016 ◽  
Vol 13 (3) ◽  
pp. 133-140 ◽  
Author(s):  
A. Li ◽  
S. Robiou-du-Pont ◽  
S. S. Anand ◽  
K. M. Morrison ◽  
S. D. McDonald ◽  
...  
Keyword(s):  
Early Life ◽  
Family Study ◽  
The Family ◽  
Genetic Contributions

Pre-Natal and Early Life Predictors Of Atopy In Canadian Children: Results Of The Family Study

2014 ◽  
Vol 133 (2) ◽  
pp. AB235
Author(s):  
Tahira Batool ◽  
Michael M. Cyr ◽  
Judah Aryeh Denburg ◽  
Karleen Schulze ◽  
Sonia Anand ◽  
...  
Keyword(s):  
Early Life ◽  
Family Study ◽  
The Family

scholarly journals Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Shanice Christie ◽  
Sébastien Robiou-du-Pont ◽  
Sonia S. Anand ◽  
Katherine M. Morrison ◽  
Sarah D. McDonald ◽  
...  
Keyword(s):  
Early Life ◽  
Family Study ◽  
Genetic Contribution ◽  
Lipid Levels ◽  
The Family

The Family Atherosclerosis Monitoring In earLY life (FAMILY) study

2009 ◽  
Vol 158 (4) ◽  
pp. 533-539 ◽  
Author(s):  
Katherine M. Morrison ◽  
Stephanie A. Atkinson ◽  
Salim Yusuf ◽  
Jacqueline Bourgeois ◽  
Sarah McDonald ◽  
...  
Keyword(s):  
Early Life ◽  
Family Study ◽  
The Family

scholarly journals Parental and offspring contribution of genetic markers of adult blood pressure in early life: The FAMILY study

PLoS ONE ◽  
2017 ◽  
Vol 12 (10) ◽  
pp. e0186218 ◽  
Author(s):  
Sébastien Robiou-du-Pont ◽  
Sonia S. Anand ◽  
Katherine M. Morrison ◽  
Sarah D. McDonald ◽  
Stephanie A. Atkinson ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Genetic Markers ◽  
Early Life ◽  
Family Study ◽  
The Family

The Dupont family: collectors, dealers and naturalists in nineteenth-century Paris

2016 ◽  
Vol 43 (2) ◽  
pp. 191-207 ◽  
Author(s):  
Richard Mearns ◽  
Laurent Chevrier ◽  
Christophe Gouraud
Keyword(s):  
Nineteenth Century ◽  
Family History ◽  
Natural History ◽  
North Africa ◽  
Special Interest ◽  
Early Life ◽  
Anatomical Models ◽  
The Family ◽  
Small Collection

In the early part of the nineteenth century the Dupont brothers ran separate natural history businesses in Paris. Relatively little is known about their early life but an investigation into the family history at Bayeux corrects Léonard Dupont's year of birth from 1795 to 1796. In 1818 Léonard joined Joseph Ritchie's expedition to North Africa to assist in collecting and preparing the discoveries but he did not get beyond Tripoli. After 15 months he came back to Paris with a small collection from Libya and Provence, and returned to Provence in 1821. While operating as a dealer-naturalist in Paris he published Traité de taxidermie (1823, 1827), developed a special interest in foreign birds and became well known for his anatomical models in coloured wax. Henry Dupont sold a range of natural history material and with his particular passion for beetles formed one of the finest collections in Europe; his best known publication is Monographie des Trachydérides (1836–1840). Because the brothers had overlapping interests and were rarely referred to by their forenames there has been confusion between them and the various eponyms that commemorate them. Although probably true, it would be an over-simplification to state that birds of this era named for Dupont refer to Léonard Dupont, insects to Henry Dupont, and molluscs to their mother.

Old Posen and Young Ernst

2018 ◽  
pp. 8-22 ◽  
Author(s):  
Robert E. Lerner
Keyword(s):  
Middle School ◽  
Early Life ◽  
Intensive Study ◽  
Modern Language ◽  
The Family

This chapter details the family and early life of Ernst Kantorowicz. Born in 1895, Kantorowicz was the youngest of three siblings. His parents believed that teaching him English was essential, based on the presumption that he would be engaged in trade. Thus, they gave him to the care of an English governess until he was twelve, and he learned to speak English well enough to be able to lecture in that language at Oxford in 1934. In the spring of 1901, when he was six, he entered a local municipal “middle-school for youths,” which he attended for three years. From the middle school he proceeded to the Royal Auguste-Viktoria Gymnasium, an all-male school that required the intensive study of Latin and Greek plus one modern language, which in Kantorowicz's case was French.

Muhammad Mustafa Badawi in Conversation

2015 ◽  
Author(s):  
Abdul-Nabi Isstaif
Keyword(s):  
Early Life ◽  
World Literature ◽  
English Language ◽  
English Literature ◽  
Arabic Literature ◽  
Literature And Politics ◽  
The Family ◽  
Essential Questions ◽  
The Relationship ◽  
The City

This chapter presents a 1997 interview with Mustafa Badawi and includes sections relating to his early life and education until 1947 when he was sent to England to pursue further studies in English. Badawi first talks about the years of his early formation in the family, the neighbourhood and his various schools in Alexandria before discussing his cultural formation in the city. He reveals that he decided to specialise in English language in order to deepen his study of English literature so that he could see Arabic literature in the wider context of world literature. Badawi also describes his attitudes towards literature and criticism, which he says involved three essential questions: the relationship between literature and politics; the relationship between literature and morality; and the nature of language and its function in poetry, and consequently the relationship between poetry and science, or between poetry and thought or knowledge in general.

David Randall Pye, 1886-1960

1961 ◽  
Vol 7 ◽  
pp. 199-205
Keyword(s):  
Early Life ◽  
Research Organization ◽  
Engineering Science ◽  
High Quality ◽  
Administrative Work ◽  
The Family ◽  
University College London ◽  
High Standards ◽  
Three Sisters ◽  
Personal Research

David Randall Pye, who died on 20 February 1960, was a scientist and an engineer, although he spent most of his life in government and university administration to which he was called at critical times. From the age of thirty-nine to fifty-seven he devoted himself to building up the scientific research organization of the Air Ministry, at a time when aeronautical developments were so vital to our country’s survival; from fifty-seven until his retirement at sixty-five, he undertook the task, as Provost, of re-establishing University College, London, which had suffered severe blows from the enemy’s air attack. Had there been no war he would almost certainly have spent his life in engineering science, probably in a university, and would have made many more original contributions of the same high quality as those of his earlier years. But although he thus sacrificed his personal research for his country’s needs, he undoubtedly did so partly because of his intense interest in human affairs and in people. He was not by any means a born administrator, or an ambitious organizer, but his wide talents, simple integrity and high standards, enabled him to achieve real success in the administrative work he undertook. Pye was born on 29 April 1886 at Hampstead, London. His early life was spent in the atmosphere of a country home not far from London where he lived with his parents, three brothers and three sisters, David being the sixth in the family. He was a descendant of John Pye of the Mynde, County Hereford, and Anne, daughter of Roger Andrews of Hereford, through their son, Walter Pye of Kilpeck Castle. Another branch of the family, the Edmund Pyes, lived at Blyth, Nottinghamshire, one of whom had a grant of arms from Sir Richard St George, Clarenceux King at Arms, 2 March 1633-1634.

A family with factor XII deficiency: a family study suggesting that factor XII levels are determined by the presence of 3 codominant alleles with variable penetrance

1981 ◽  
Author(s):  
D Roberts ◽  
O Hayne ◽  
E Fraser
Keyword(s):  
General Population ◽  
Family Study ◽  
Controlling Factor ◽  
Factor Xii ◽  
Factor Xii Deficiency ◽  
The Family ◽  
Variable Penetrance

We studied 15 members, in 3 generations of a family in whom the propositus had complete factor XII deficiency. The parents had factor XII levels of 59% and 62%. Three of the siblings had factor XII levels of less than 1%. Three more had factor XII levels of (30±5%). In 3 the levels ranged from (60-87%) and the remaining 2 siblings had levels exceeding 100%. The propositus with a level of less than 1% gave rise to an offspring with a level of 48%.We propose that the gene controlling factor XII production consists of 3 separate alleles expressed codominantly: A - normal, B - low, O - absent. Members of the family with 100% factor XII activity have genotype AA; those with less than 1% activity have genotype OO; subjects with levels of 30% have genotype BO, and those with levels of 60% have genotype AO. We feel our study sheds new light on the inheritance of factor XII and the wide variation of levels in the general population.

scholarly journals Genetic and Environmental Influences on General Skin Traits: Healthy Twins and Families in Korea

2016 ◽  
Vol 20 (1) ◽  
pp. 36-42 ◽  
Author(s):  
Young Ju Suh ◽  
Jeonghyun Shin ◽  
Moonil Kang ◽  
Hyun Ju Park ◽  
Kayoung Lee ◽  
...  
Keyword(s):  
Family Relationships ◽  
Genetic Variants ◽  
Family Study ◽  
Monozygotic Twin ◽  
Genetic Influences ◽  
Genetic Studies ◽  
Variance Component Method ◽  
Melanin Index ◽  
Genetic Contributions ◽  
Sebum Secretion

Family study can provide estimates of overall genetic influences on a particular trait because family relationships provide accurate measures of average genetic sharing. However, evidence of genetic contributions to skin phenotypes is limited, which may preclude genetic studies to identify genetic variants or to understand underlying molecular biology of skin traits. This study aimed to estimate genetic and environmental contributions to selected dermatologic phenotypes, that is, to melanin index, sebum secretion, and skin humidity level in a Korean twin-family cohort. We investigated more than 2,000 individuals from 486 families, including 388 monozygotic twin pairs and 82 dizygotic twin pairs. Variance component method was used to estimate genetic influences in terms of heritability. Heritability of skin melanin index, sebum secretion, and skin humidity (arm and cheek) were estimated to be 0.44 [95% CI 0.38–0.49], 0.21 [95% CI 0.16–0.26], 0.13 [95% CI 0.07–0.18], and 0.11 [95% CI 0.06–0.16] respectively, after adjusting for confounding factors. Our findings suggest that genetics play a major role on skin melanin index, but only mild roles on sebum secretion and humidity. Sebum secretion and skin humidity are controlled predominantly by environmental factors notably on shared environments among family members. We expect that our findings add insight to determinants of common dermatologic traits, and serve as a reference for biologic studies.

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