Nucleotide sequence and polymorphism of MHC class IIDQBexon 2 alleles in Chinese yakow (Bos grunniens × Bos taurus)

2014 ◽  
Vol 41 (3) ◽  
pp. 269-275 ◽  
Author(s):  
D. Xi ◽  
T. Hao ◽  
Y. He ◽  
J. Leng ◽  
Y. Sun ◽  
...  
2017 ◽  
Vol 95 (10) ◽  
pp. 4600-4612 ◽  
Author(s):  
J. W. Zhou ◽  
C. L. Zhong ◽  
H. Liu ◽  
A. A. Degen ◽  
E. C. Titgemeyer ◽  
...  

2019 ◽  
Vol 33 (4) ◽  
pp. 546-551 ◽  
Author(s):  
C. M. Calkins ◽  
J. D. Scasta ◽  
T. Smith ◽  
M. M. Stayton ◽  
S. L. Lake

2017 ◽  
Vol 41 ◽  
pp. 136-141
Author(s):  
Dongmei XI ◽  
Sameeullah MEMON ◽  
Guozhi LI ◽  
Xiangying LIU ◽  
Chao SU ◽  
...  

2021 ◽  
Author(s):  
Congcong Zhao ◽  
Lamei Wang ◽  
Shanlin Ke ◽  
Xinhua Chen ◽  
Ákos Kenéz ◽  
...  

Abstract Background Rumen microbes play an important role in ruminant energy supply and animal performance. Previous studies showed that yak (Bos grunniens) rumen microbiome and fermentation differ from other ruminants. However, little is understood on the features of the rumen microbiome that make yak adapted to its unique environmental and dietary conditions. Here we investigated the rumen microbiome and metabolome to understand how yak adapts to the coarse forage and harsh environment in the high Qinghai-Tibetan plateau. Result Metataxonomic analysis of the rumen microbiota revealed that yak (Bos grunniens), domesticated cattle (Bos taurus), and dzo (a hybrid between the yak and domestic cattle) have distinct rumen microbiota. Metagenomic analysis displayed a larger gene pool encoding a richer repertoire of carbohydrate-active enzymes (CAZymes) in the rumen microbiome of yak and dzo than cattle. Some of the genes encoding glycoside hydrolases (GH) that mediate the digestion of cellulose and hemicellulose were significantly enriched in the rumen of yak than cattle, but the cattle rumen microbiome had more genes assigned to GH57 that primarily includes amylases. The rumen fermentation profile differed also, with cattle having a higher molar proportion of acetate but a lower molar proportion of propionate than dzo and yak. Metabolomic analysis showed differences in both rumen microbial metabolic pathways and metabolites, mainly amino acids, carboxylic acids, sugars, and bile acids. Notably, styrene degradation, primary bile acid biosynthesis, glyoxylate, and dicarboxylate metabolism significantly differed between cattle and dzo; streptomycin biosynthesis was significantly different between cattle and yak; and the pathways for biotin metabolism and styrene degradation significantly differed between dzo and yak. Correlation analysis revealed certain microbial species correlated with differential rumen metabolites. Nine differential metabolites showed a positive correlation with seven species belonging to Bacteroides and Alistipes but a negative correlation with ten species belonging to Prevotella and Ruminococcus. Conclusion The present study showed that the rumen microbiome of yak and its host had probably co-evolved aiding in the adaptation of yak to the harsh dietary environment of the Qinghai-Tibetan plateau. In particular, the yak rumen microbiome has more enzymes involved in the degradation of rough forage than that of cattle, providing sufficient energy for its host.


2022 ◽  
Vol 335 ◽  
pp. 00014
Author(s):  
R. Misrianti ◽  
S.H. Wijaya ◽  
C. Sumantri ◽  
J. Jakaria

Mitochondria DNA (mtDNA) as a source of genetic information based on the maternal genome, can provide important information for phylogenetic analysis and evolutionary biology. The objective of this study was to analyze the phylogenetic tree of Bali cattle with seven gene bank references (Bos indicus, Bos taurus, Bos frontalis, and Bos grunniens) based on partial sequence 16S rRNA mitochondria DNA. The Bayesian phylogenetic tree was constructed using BEAST 2.4. and visualization in Figtree 1.4.4 (tree.bio.ed.ac.uk/software/figtree/). The best model of evolution was carried out using jModelTest 2.1.7. The most optimal was the evolutionary models GTR + I + G with p-inv (I) 0,1990 and gamma shape 0.1960. The main result indicated that the Bali cattle were grouped into Bos javanicus. Phylogenetic analysis also successfully classifying Bos javanicus, Bos indicus, Bos taurus, Bos frontalis and Bos grunniens. These results will complete information about Bali cattle and useful for the preservation and conservation strategies of Indonesian animal genetic resources.


2019 ◽  
Author(s):  
Jiabo Wang ◽  
Zhixin Chai ◽  
Lei Deng ◽  
Jikun Wang ◽  
Hui Wang ◽  
...  

Abstract Background: Yaks, which are known as “The ship in the Plateau”, play an important role in the life of people on the Qinghai-Tibet Plateau. There are many potential genetic advantages for Plateau Adaptation(PA) of Yak to improve breeding and adapt the environment with low oxygen and strong ultraviolet ray. In this study, in order to filter the Different Expression (DE) genes and new long non-coding RNAs (lncRNAs) ,also reveal underlying co-expression and regulation network of these, we sequenced 18 samples (cerebellum and cerebrum) of Bos Taurus, Bos Grunniens ☓ Bos Taurus and Bos Grunniens (3 individuals as replications for each species), ,and compared the relationship between modules and PA trait basing on the background of crossbreed genetics. Generalized linear model was used to analyze DE genes, and the different tissues as adjust variations in the model can reduce the noise of population structure. Results: On average, 50 million clean reads for each sample were obtained by the control of data quality. 12,072 pseudo lncRNAs were predicted in intersection of three software (CPC2, CNCI and CPAT). Total 4,257 significant DE transcripts were identified by using Ballgown R package (P<0.01) , 1021 of which were protein coding genes, 14were known lncRNAs, 661 were novel lncRNAs. By WGCNA, a co-expression network of DE mRNAs and lncRNAs with 6 modules was created to present functional relationship with PA trait. Our study provided a valuable sub-network composed by 8 hub genes (GRAMD3, MAST4, MICAL1, TLE1, ERAP1, PINK1, MRPL49 and IL34),.1of them was known lncRNA (LOC106700748) ,5 were novel lncRNAs (MSTRG247.1, MSTRG431.1, MSTRG422.1, MSTRG327.1 and MSTRG97.1) in the major module of the whole network. Conclusions: The functions of those hub genes are associated with blood pressure, reactive oxygen and metabolic process. The analysis of co-expressed genes with PA trait provides a reference way of the regulation mechanisms in PA of Yak and gets a reference method of the additive genetics expression detection between crossbreed and parents population as well.


Author(s):  
David J. Marsh ◽  
Sodovyn Damdinsuren ◽  
Olga Bordanova ◽  
Jamgany Tserendendev ◽  
Tüvdengiin Gung-Aajav

2011 ◽  
Vol 24 (6) ◽  
pp. 766-773 ◽  
Author(s):  
Hucheng Wang ◽  
Ruijun Long ◽  
Juan Boo Liang ◽  
Xusheng Guo ◽  
Luming Ding ◽  
...  

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