Maintenance of good glycaemic control is challenging – A cohort study of type 2 diabetes patient in North Karelia, Finland

2019 ◽  
Vol 73 (4) ◽  
pp. e13313 ◽  
Author(s):  
Nazma Akter Nazu ◽  
Jaana Lindström ◽  
Päivi Rautiainen ◽  
Hilkka Tirkkonen ◽  
Katja Wikström ◽  
...  
2015 ◽  
Vol 17 (8) ◽  
pp. 771-780 ◽  
Author(s):  
R. W. Thomsen ◽  
L. M. Baggesen ◽  
E. Svensson ◽  
L. Pedersen ◽  
H. Nørrelund ◽  
...  

2020 ◽  
Vol 2 (9) ◽  
pp. 496-502
Author(s):  
Hannah Syed

Intensive treatment with insulin and sulfonylureas in older people with low HbA1c (<53mmol/mol) can increase the risk of hypoglycaemia, morbidity and mortality. Older people, particularly those with frailty and/or comorbidities are less likely to benefit from the long-term protective effects of good glycaemic control and are often at risk of inappropriate polypharmacy. A person-centred holistic approach to diabetes management must be adapted for older people living with diabetes.


2012 ◽  
Vol 105 (7) ◽  
pp. 300-308 ◽  
Author(s):  
Gareth D James ◽  
Peter Baker ◽  
Ellena Badrick ◽  
Rohini Mathur ◽  
Sally Hull ◽  
...  

Pneumologie ◽  
2017 ◽  
Vol 71 (S 01) ◽  
pp. S1-S125
Author(s):  
R Russell ◽  
D Price ◽  
R Mares ◽  
A Burden ◽  
D Skinner ◽  
...  

1996 ◽  
Vol 89 (1) ◽  
pp. 27-30 ◽  
Author(s):  
B J Boucher ◽  
J Tsoumanis ◽  
K Noonan ◽  
J Holmes

Glycosylated haemoglobins and weights were recorded for 200 consecutive diabetic clinic attendere seen yearly for 5 years, 76 of whom were also seen up to 10 years from diagnosis of type 2 diabetes, representing 1380 patient years. Weight fluctuation (≥3 kg) was associated with increased final prevalence of hypertension, macroalbuminaemia and a raised creatinine (P≤ 0.002) but this relationship was abolished by correction for higher initial weight. Average giycaemia over 5/10 years [itself related to initial weight in women on tablets (N=53) but not others, and to waist but not waist/hip ratio], correlated with prevalence and severity of retinopathy (N=200; r=0.38, P≤0.0006) seen also in the subgroup of patients on tablets (N=145, P≤0.006). At HbA1 levels ≥10.5% an increased prevelance of retinopathy was seen in those on insulin (W=37, P≤0.001) and an increased prevalence of peripheral vascular disease was seen in men but not women (x2=2.87, P≤0.01) as well as in the prevalence of neuropathy. These findings suggest that good glycaemic control is of value in type 2 diabetes and less easily achieved in obesity.


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