scholarly journals Influence of the replacement of silica by boron trioxide on the properties of bioactive glass scaffolds

Author(s):  
Katharina Schuhladen ◽  
Usanee Pantulap ◽  
Kristin Engel ◽  
Piotr Jeleń ◽  
Zbigniew Olejniczak ◽  
...  
2021 ◽  
Vol 37 (6) ◽  
pp. 1409-1414
Author(s):  
Neeraj Gupta ◽  
Vikash Kumar Vyas ◽  
Apurba Mandal

Bioactive glass is mainly familiar for its outstanding biocompatibility and bioactive behavior and it’s known for important bone bonding ability. Bioactive glass is a reproduction fillet joint meant for orthopedic in addition to periodontal function of one of the leading applications. A silica based bioactive glass designated 1393 bio-glass® [wt. % (53) SiO2 – (6) Na2O – (12) K2O – (20) CaO – (5) MgO – (4)P2O5] 1393 is like 45S5 bio-glass®, other than it has a high SiO2 content and network modifiers, such as potassium oxide and magnesium oxide, bioactive glass, is also used clinically. In this communication, study of destructive (DT) & non-destructive (NDT) behavior of SiO2 replaced by boron trioxide (B2O3) in 1393 bioactive glass has been reported. The formed amorphous phase using x-ray diffraction (X-RD) analysis in bioactive glass will be identified. Density and mechanical properties measured using different types of instrument and using ultrasonic wave velocities study the elastic properties like young’s , shear, bulk modulus and Poisson’s ratio of bioactive glasses were reported. The results point to the substitution of boron trioxide in 1393 bioactive glass enhanced its density, mechanical properties and elastic properties, similarly for silica.


Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
RFA Bonfim ◽  
VR Chitarra ◽  
RT Gomes ◽  
RD Zacarias ◽  
VR Santos ◽  
...  

1996 ◽  
Vol 9 (3) ◽  
Author(s):  
P. Stoor ◽  
V. Kirstilä ◽  
E. Söderling ◽  
I. Kangasniemi ◽  
K. Herbst ◽  
...  

2013 ◽  
Vol 28 (10) ◽  
pp. 1137-1142
Author(s):  
Xiang ZHANG ◽  
Da-Li ZHOU ◽  
Qin LONG ◽  
Jia-Bei ZHOU ◽  
Yan-Fei TAN ◽  
...  

2011 ◽  
Vol 26 (8) ◽  
pp. 869-873
Author(s):  
Xue HAN ◽  
Xiao-Feng CHEN ◽  
Yong-Chun MENG ◽  
Jia-An ZHOU ◽  
Cai LIN ◽  
...  

2019 ◽  
Vol 70 (6) ◽  
pp. 1983-1987
Author(s):  
Cristian Trambitas ◽  
Anca Maria Pop ◽  
Alina Dia Trambitas Miron ◽  
Dorin Constantin Dorobantu ◽  
Flaviu Tabaran ◽  
...  

Large bone defects are a medical concern as these are often unable to heal spontaneously, based on the host bone repair mechanisms. In their treatment, bone tissue engineering techniques represent a promising approach by providing a guide for osseous regeneration. As bioactive glasses proved to have osteoconductive and osteoinductive properties, the aim of our study was to evaluate by histologic examination, the differences in the healing of critical-sized calvarial bone defects filled with bioactive glass combined with adipose-derived mesenchymal stem cells, compared to negative controls. We used 16 male Wistar rats subjected to a specific protocol based on which 2 calvarial bone defects were created in each animal, one was filled with Bon Alive S53P4 bioactive glass and adipose-derived stem cells and the other one was considered control. At intervals of one week during the following month, the animals were euthanized and the specimens from bone defects were histologically examined and compared. The results showed that this biomaterial was biocompatible and the first signs of osseous healing appeared in the third week. Bone Alive S53P4 bioactive glass could be an excellent bone substitute, reducing the need of bone grafts.


2018 ◽  
Vol 69 (2) ◽  
pp. 429-433
Author(s):  
Solyom Arpad ◽  
Cristian Trambitas ◽  
Ecaterina Matei ◽  
Eugeniu Vasile ◽  
Fodor Pal ◽  
...  

Osteoplasty, is a procedure mostly applied in complicated bone fractures. Nowadays this method is widely used in primary fracture treatment while the native bone graft is progressively replaced with various synthetic bone substitutes. From the numerous bone grafts we�d like to mention a representative of ceramics, the S53P4 bioactive glass. (BonAlive�). The aim of this study was to investigate the healing process of different fracture types generated on rabbit femurs. During this experiment we used seven common European rabbits. We separated these animals into two groups; in the first group we surgically generated a total fracture in the middle 1/3 of the femur, while in the second group, we produced only a bone defect on the femur. The osteoplasty was carried out with bioactive glass and autologous bone grafts. The radiographic follow-up was immediate after the operation and after 3, 6 and 7 weeks. The animals were euthanized after 19, 20 and 21 weeks, for histomorphometric examination of the femur. It was also studied the ionic release from the used bioactive glass at physiological pH and the etching of the glass was studied by Scanning Electron Microscopy.


2020 ◽  
Vol 125 (3) ◽  
pp. 217-225
Author(s):  
Torstein Grønseth ◽  
Lene K. Vestby ◽  
Live L. Nesse ◽  
Magnus von Unge ◽  
Juha T. Silvola

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