Ceramics based on calcium phosphates substituted with magnesium ions for bone regeneration

2019 ◽  
Vol 17 (1) ◽  
pp. 342-353 ◽  
Author(s):  
Cristina‐Daniela Ghițulică ◽  
Andreia Cucuruz ◽  
Georgeta Voicu ◽  
Andrei T. Cucuruz ◽  
Sorina Dinescu ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Calcium Phosphates ◽  
Magnesium Ions

The role of magnesium ions in bone regeneration involves the canonical Wnt signaling pathway

2019 ◽  
Vol 98 ◽  
pp. 246-255 ◽  
Author(s):  
Chu-Chih Hung ◽  
Amy Chaya ◽  
Kai Liu ◽  
Konstantinos Verdelis ◽  
Charles Sfeir
Keyword(s):  
Wnt Signaling ◽  
Bone Regeneration ◽  
Signaling Pathway ◽  
Wnt Signaling Pathway ◽  
Magnesium Ions ◽  
Canonical Wnt Signaling ◽  
Canonical Wnt

Influence of calcium phosphates incorporation into poly(lactic-co-glycolic acid) electrospun membranes for guided bone regeneration

2020 ◽  
Vol 179 ◽  
pp. 109253
Author(s):  
Vivian Inês dos Santos ◽  
Claudia Merlini ◽  
Águedo Aragones ◽  
Karina Cesca ◽  
Márcio Celso Fredel
Keyword(s):  
Bone Regeneration ◽  
Glycolic Acid ◽  
Calcium Phosphates ◽  
Guided Bone Regeneration ◽  
Electrospun Membranes

The effect of magnesium ions on the precipitation of calcium phosphates

1990 ◽  
Vol 106 (2-3) ◽  
pp. 355-366 ◽  
Author(s):  
W. Kibalczyc ◽  
J. Christoffersen ◽  
M.R. Christoffersen ◽  
A. Zielenkiewicz ◽  
W. Zielenkiewicz
Keyword(s):  
Calcium Phosphates ◽  
Magnesium Ions

scholarly journals Resorbable Mg2+-Containing Phosphates for Bone Tissue Repair

2021 ◽  
Author(s):  
Gilyana Kazakova ◽  
Tatiana Safronova ◽  
Daniil Golubchikov ◽  
Olga Shevtsova ◽  
Julietta Rau
Keyword(s):  
Bone Regeneration ◽  
Bone Tissue ◽  
Tissue Repair ◽  
Early Stage ◽  
Biological Properties ◽  
Magnesium Ions ◽  
Comprehensive Overview ◽  
Phosphate Ions ◽  
Great Relevance

Materials based on Mg2+-containing phosphates are gaining great relevance in the field of bone tissue repair via regenerative medicine methods. Magnesium ions, together with condensed phosphate ions, play a significant role in the process of bone remodeling, affecting the early stage of bone regeneration through active participation in the process of osteosynthesis. Here we pro-vide a comprehensive overview of the usage of biomaterials based on magnesium phosphate and magnesium calcium phosphate in bone reconstruction. The role of magnesium ions in angiogene-sis, an important process associated with osteogenesis, is considered. Finally, the biological properties of magnesium phosphates for bone regeneration are summarized. They show promis-ing results in terms of use as bone replacement material.

scholarly journals Enhancement of Bone Regeneration on Calcium-Phosphate-Coated Magnesium Mesh: Using the Rat Calvarial Model

2021 ◽  
Vol 9 ◽  
Author(s):  
Shuang Wu ◽  
Yong-Seok Jang ◽  
Min-Ho Lee
Keyword(s):  
Bone Regeneration ◽  
Surface Properties ◽  
Critical Size ◽  
Calcium Phosphates ◽  
Cell Seeding ◽  
Critical Size Defect ◽  
Direct Cell ◽  
Cell Affinity ◽  
Biodegradable Magnesium

Metallic biodegradable magnesium (Mg) is a promising material in the biomedical field owing to its excellent biocompatibility, bioabsorbability, and biomechanical characteristics. Calcium phosphates (CaPs) were coated on the surface of pure Mg through a simple alkali-hydrothermal treatment. The surface properties of CaP coatings formed on Mg were identified through wettability, direct cell seeding, and release tests since the surface properties of biomaterials can affect the reaction of the host tissue. The effect of CaP-coated Mg mesh on guided bone regeneration in rat calvaria with the critical-size defect was also evaluated in vivo using several comprehensive analyses in comparison with untreated Mg mesh. Following the application of protective CaP coating, the surface energy of Mg improved with higher hydrophilicity and cell affinity. At the same time, the CaP coating endowed Mg with higher Ca affinity and lower degradation. The Mg mesh with CaP coating had higher osteointegration and bone affinity than pristine Mg mesh.

scholarly journals Biodegradable Polymers as Drug Delivery Systems for Bone Regeneration

Pharmaceutics ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 95 ◽  
Author(s):  
Kaoru Aoki ◽  
Naoto Saito
Keyword(s):  
Drug Delivery ◽  
Regenerative Medicine ◽  
Bone Regeneration ◽  
Drug Delivery Systems ◽  
Calcium Phosphates ◽  
Delivery Systems ◽  
Polymer Scaffolds ◽  
Synthetic Scaffold ◽  
And Performance ◽  
Potential Use

Regenerative medicine has been widely researched for the treatment of bone defects. In the field of bone regenerative medicine, signaling molecules and the use of scaffolds are of particular importance as drug delivery systems (DDS) or carriers for cell differentiation, and various materials have been explored for their potential use. Although calcium phosphates such as hydroxyapatite and tricalcium phosphate are clinically used as synthetic scaffold material for bone regeneration, biodegradable materials have attracted much attention in recent years for their clinical application as scaffolds due their ability to facilitate rapid localized absorption and replacement with autologous bone. In this review, we introduce the types, features, and performance characteristics of biodegradable polymer scaffolds in their role as DDS for bone regeneration therapy.

Sign in / Sign up

Export Citation Format

Share Document