scholarly journals Efficacy of local anaesthetic solutions on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a systematic review and network meta‐analysis of randomized clinical trials

2019 ◽  
Vol 52 (6) ◽  
pp. 779-789 ◽  
Author(s):  
V. Nagendrababu ◽  
S. J. Pulikkotil ◽  
A. Suresh ◽  
S. K. Veettil ◽  
S. Bhatia ◽  
...  
2018 ◽  
Vol 12 (1) ◽  
pp. 340-346 ◽  
Author(s):  
Gowri Sivaramakrishnan ◽  
Kannan Sridharan

Background: Ketorolac has advantages over other analgesics as a pre-anaesthetic medication. Considering this in mind, the present meta-analysis aims to identify the effect of oral ketorolac premedication on the anaesthetic efficacy of Inferior Alveolar Nerve Block (IANB) in patients with irreversible pulpitis. Methods: Full-texts of eligible studies were obtained from electronic databases. The extracted data was analysed using non-Cochrane mode in RevMan 5.0 software. Relative risk [95% CI] was calculated for the success of IANB. Results: Four studies were included for the final review. The success rate of IANB on 221 patients with relative risk of 1.87 [1.36, 2.56] was statistically significant favouring ketorolac. The mean difference for VAS in 171 patients was not statistically significant {-13.55 [-33.91, 6.82]}. Conclusion: Oral ketorolac can be successfully administered as a premedication before conventional inferior alveolar nerve block for endodontic treatment for irreversible pulpitis.


2018 ◽  
Vol 45 (2) ◽  
pp. 246-258 ◽  
Author(s):  
Juliana L. Geus ◽  
Leticia M. Wambier ◽  
Thaynara F. Boing ◽  
Alessandro D. Loguercio ◽  
Alessandra Reis

2019 ◽  
Vol 2019 ◽  
pp. 1-25 ◽  
Author(s):  
Meric Karapinar-Kazandag ◽  
Jale Tanalp ◽  
Handan Ersev

Background. Failure in the provision of inferior alveolar nerve block anesthesia (IANB) is a significant problem during endodontic treatment of irreversible pulpitis. Various methodologies have been advocated one of which is administration of premedication prior to anesthesia. Despite the considerable number of reports, the topic yet deserves more clarification. This systematic review was conducted to provide an oversight on the effectiveness of premedication prior to IANB in mandibular teeth. Methods. A PubMed and Cochrane Database search was conducted by using MeSH terms inferior alveolar nerve block + pulpitis and mandibular anesthesia+pulpitis. Two reviewers independently performed the screening, selection of papers, and data extraction. Papers in English language that included randomized clinical studies on the impact of different medications on the success of inferior alveolar block anesthesia in irreversible pulpitis were included. Additionally, relevant supporting literature was also used where necessary. Results. Initially, 118 papers were selected from PubMed and 68 were selected from Cochrane. Five additional articles were retrieved from Google Search. Following the elimination of duplicates and irrelevant articles, 35 studies were selected meeting the criteria. It was observed that there was moderate evidence to suggest that some premedications were partially effective for the enhancement of mandibular anesthetic effect in irreversible pulpitis. Conclusion. Though some medications appear to be promising, further supporting research will help highlight this significant topic which requires further clarification.


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