scholarly journals A randomised clinical study to evaluate the effect of brushing duration on fluoride levels in dental biofilm fluid and saliva in children aged 4–5 years

2013 ◽  
Vol 63 ◽  
pp. 39-47 ◽  
Author(s):  
Evelyn E. Newby ◽  
Esperanza A. Martinez-Mier ◽  
Domenick T. Zero ◽  
Sue A. Kelly ◽  
Nancy Fleming ◽  
...  
Keyword(s):  
Clinical Study ◽  
Dental Biofilm ◽  
Biofilm Fluid

Fluoride formed on enamel by fluoride varnish or gel application: A randomized controlled clinical trial

2021 ◽  
Author(s):  
Mauro Antonio Dall Agnol ◽  
Carla Battiston ◽  
Livia Maria Andalo Tenuta ◽  
Jaime Aparecido Cury
Keyword(s):  
Chemical Reactivity ◽  
Fluoride Concentration ◽  
Negative Control ◽  
Fluoride Varnish ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Dental Biofilm ◽  
Initial Application ◽  
Biofilm Fluid

Although fluoride varnish (FV) and acidulated phosphate fluoride gel (APF-gel) are considered clinically effective to reduce caries, in vitro studies have shown that FV reacts slowly with enamel because most NaF present in the formulation is not solubilized in the FV. Therefore, we conducted a clinical study to evaluate if the time that FV remains on dental surfaces could overcome its slower chemical reactivity when compared with APF-gel. Sixty-eight volunteers were randomly allocated into four groups: Negative control (Control, no treatment), APF -gel application (1.23% F applied for 4 min), and FV application (Duraphat®, 2.26 % F) for 4 h (FV-4h) or 24 h (FV-24h). To evaluate fluoride formed and retained on enamel, acid biopsies were made on the buccal surfaces of the maxillary central incisors before, at the end of the application of fluoride products (immediately after gel application, or after 4 or 24 h of varnish application) and after 7 and 28 days. Fluoride concentration in dental biofilm was also analyzed before and up to 28 days after initial application. The data were analyzed by 2-way ANOVA, considering treatment and time as factors. The APF-gel and FV-24h groups formed greater fluoride concentration on enamel than the FV-4h and the control group at the end of application (p=0.0001), with no difference from each other (p=0.99). The groups did not differ regarding fluoride in biofilm, fluid (p=0.73) and solids (0.40). In conclusion, fluoride varnish needs to remain in contact with the teeth for prolonged times (>4 h) to reach the same reactivity obtained by a 4-min application of APF-gel.

Fluoride in Dental Biofilm Varies across Intra-Oral Regions

2017 ◽  
Vol 51 (4) ◽  
pp. 402-409 ◽  
Author(s):  
Line Staun Larsen ◽  
Vibeke Baelum ◽  
Livia Maria Andaló Tenuta ◽  
Alan Richards ◽  
Bente Nyvad
Keyword(s):  
Sampling Site ◽  
Fluoride Concentration ◽  
Cross Sectional Study ◽  
Anterior Region ◽  
Cross Sectional ◽  
Dental Biofilm ◽  
Whole Saliva ◽  
Biofilm Fluid ◽  
Fluoride Distribution ◽  
Unstimulated Whole Saliva

Information on differences in biofilm fluoride concentration across intra-oral regions may help explain the distribution of caries within the dentition. The aim of this cross-sectional study was to describe the fluoride concentration in saliva and in biofilm fluid and biofilm solids across 6 intra-oral regions. Unstimulated whole saliva was collected from 42 participants and biofilm harvested from the buccal sites in the 4 molar and 2 anterior regions. Samples were collected at least 1 h after use of fluoride dentifrice. No attempt was made to control the participants' food consumption or use of other topical agents. Centrifuged saliva, biofilm fluid, and biofilm solids were analysed for fluoride using a fluoride ion-selective electrode, adapted for microanalysis. Fluoride in biofilm varied across intra-oral regions. The mean biofilm fluid fluoride concentrations across the oral cavity ranged from 11.6 to 16.8 µM, being statistically significantly higher in the upper anterior region than in any other region. In all regions the fluoride concentration in biofilm fluid was higher than in saliva. For biofilm solids the fluoride concentration was highest in the lower anterior region (2,461 μmol/kg) and lowest in the lower molar regions (388 and 406 μmol/kg, respectively). Within biofilm, the solids contained most of the fluoride (81 to >99%). The biofilm fluid fluoride concentration was significantly positively associated with salivary fluoride and only marginally associated with that of biofilm solids. In conclusion, this study has shown pronounced differences in fluoride distribution across intra-oral regions and compartments. This shows that the sampling site is a crucial factor for studies of biofilm fluoride.

A Clinical Study of Twenty-seven Children Exhibiting Functional Hearing Loss

1981 ◽  
Vol 12 (1) ◽  
pp. 26-35 ◽  
Author(s):  
Donald L. McCanna ◽  
Giacinto DeLapa
Keyword(s):  
Hearing Loss ◽  
Clinical Study ◽  
Early Identification ◽  
Behavioral Responses ◽  
Upper Elementary ◽  
Elementary Grades ◽  
Ability Level ◽  
Hearing Problem

This report reviews 27 cases of children exhibiting functional hearing loss. The study reveals that most students were in the upper elementary grades and were predominantly females. These subjects were functioning below their ability level in school and were usually in conflict with school, home, or peers. Tests used were selected on the basis of their helping to provide early identification. The subjects' oral and behavioral responses are presented, as well as ways of resolving the hearing problem. Some helpful counseling techniques are also presented.

Entergastrone Parenterally in the Treatment of Peptic Ulcer: A Controlled Clinical Study

1951 ◽  
Vol 17 (1) ◽  
pp. 35-38 ◽  
Author(s):  
Frank C. Bone ◽  
Chester Cassel ◽  
Julian M. Ruffin ◽  
Robert J. Reeves
Keyword(s):  
Peptic Ulcer ◽  
Clinical Study ◽  
Controlled Clinical Study

Clinical Study of Five-Year Survivors After Surgery for Gastric Carcinoma

1961 ◽  
Vol 40 (2) ◽  
pp. 188-196 ◽  
Author(s):  
Charles H. Brown ◽  
Mauro Merlo ◽  
John B. Hazard
Keyword(s):  
Clinical Study ◽  
Gastric Carcinoma

589: Tissue Engineered Tubularized Urethra for Surgical Reconstruction: A Pre-Clinical Study

2007 ◽  
Vol 177 (4S) ◽  
pp. 197-197 ◽  
Author(s):  
Hazem O. Orabi ◽  
Tamer A. Aboushwareb ◽  
Yuan Yuan Zhang ◽  
James J. Yoo ◽  
Anthony Atala
Keyword(s):  
Clinical Study ◽  
Surgical Reconstruction

A photoelastic clinical study of the static load distributionat the stump/socket interface of PTB sockets

2005 ◽  
Vol 29 (3) ◽  
pp. 291-302 ◽  
Author(s):  
P. Sewell ◽  
J. Vinney ◽  
S. Noroozi ◽  
R. Amali ◽  
S. Andrews
Keyword(s):  
Clinical Study ◽  
Static Load ◽  
Socket Interface
Sign in / Sign up

Export Citation Format

Share Document