scholarly journals Survival outcomes in liver transplant recipients with Model for End‐stage Liver Disease scores of 40 or higher: a decade‐long experience

HPB ◽  
2015 ◽  
Vol 17 (12) ◽  
pp. 1074-1084 ◽  
Author(s):  
Hina J. Panchal ◽  
Joel B. Durinka ◽  
Jeromy Patterson ◽  
Farah Karipineni ◽  
Sarah Ashburn ◽  
...  
2020 ◽  
pp. 152692482097860
Author(s):  
Kathryn H. Melamed ◽  
David Dai ◽  
Natasha Cuk ◽  
Daniela Markovic ◽  
Robert Follett ◽  
...  

Introduction: Trapped lung, characterized by atelectatic lung unable to reexpand and fill the thoracic cavity due to a restricting fibrous visceral pleural peel, is occasionally seen in patients with end-stage liver disease complicated by hepatic hydrothorax. Limited data suggest that trapped lung prior to orthotopic liver transplantation may be associated with poor outcomes. Research Question: What is the clinical significance of trapped lung in patients receiving orthotopic liver transplantation? Design: We performed a retrospective analysis of patients who underwent liver transplantation over an 8-year period. Baseline clinical characteristics and postoperative outcomes of adult patients with trapped lung were analyzed and compared to the overall cohort of liver transplant recipients and controls matched 3:1 based on age, sex, Model for End-Stage Liver Disease (MELD) score, and presence of pleural effusion. Results: Of the 1193 patients who underwent liver transplantation, we identified 20 patients (1.68%) with trapped lung. The probability of 1 and 2-year survival were 75.0% and 57.1%, compared to 85.6% and 80.4% (p = 0.02) in all liver transplant recipients and 87.9% and 81.1% (p = 0.03) in matched controls respectively. Patients with trapped lung had a longer hospital length of stay compared to the total liver transplant population (geometric mean 54.9 ± 8.4 vs. 27.2 ± 0.7 days, p ≤ 0.001), when adjusted for age and MELD score. Discussion: Patients with trapped prior to orthotopic liver transplantation have increased probability of mortality as well as increased health care utilization. This is a small retrospective analysis, and further prospective investigation is warranted.


Critical Care ◽  
2010 ◽  
Vol 14 (3) ◽  
pp. R117 ◽  
Author(s):  
Christian E Oberkofler ◽  
Philipp Dutkowski ◽  
Reto Stocker ◽  
Reto A Schuepbach ◽  
John F Stover ◽  
...  

2013 ◽  
Vol 19 (9) ◽  
pp. 1011-1019 ◽  
Author(s):  
Maristela Pinheiro Freire ◽  
Isabel C. V. Soares Oshiro ◽  
Patricia Rodrigues Bonazzi ◽  
Thais Guimarães ◽  
Estela Regina Ramos Figueira ◽  
...  

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