Clinical efficiency of inhibitory control test for the diagnosis of minimal hepatic encephalopathy: A systematic review with meta‐analysis

2021 ◽  
Author(s):  
Ming Luo ◽  
Xiao‐Fei Li ◽  
Sheng‐Juan Hu ◽  
Fei‐Hu Bai
Keyword(s):  
Systematic Review ◽  
Hepatic Encephalopathy ◽  
Inhibitory Control ◽  
Meta Analysis ◽  
Minimal Hepatic Encephalopathy ◽  
Control Test ◽  
Clinical Efficiency ◽  
Inhibitory Control Test

Value of the Inhibitory Control Test for the Diagnosis of Minimal Hepatic Encephalopathy

2011 ◽  
Vol 140 (5) ◽  
pp. S-958
Author(s):  
Radha K. Dhiman ◽  
Sunil Taneja ◽  
Amit Khatri ◽  
Sandeep Goyal ◽  
Kiran K. Thumburu ◽  
...  
Keyword(s):  
Hepatic Encephalopathy ◽  
Inhibitory Control ◽  
Minimal Hepatic Encephalopathy ◽  
Control Test ◽  
Inhibitory Control Test

Inhibitory Control Test for the Diagnosis of Minimal Hepatic Encephalopathy

2008 ◽  
Vol 135 (5) ◽  
pp. 1591-1600.e1 ◽  
Author(s):  
Jasmohan S. Bajaj ◽  
Muhammad Hafeezullah ◽  
Jose Franco ◽  
Rajiv R. Varma ◽  
Raymond G. Hoffmann ◽  
...  
Keyword(s):  
Hepatic Encephalopathy ◽  
Inhibitory Control ◽  
Minimal Hepatic Encephalopathy ◽  
Control Test ◽  
Inhibitory Control Test

scholarly journals Clinical Usefulness of the Inhibitory Control Test (ICT) in the Diagnosis of Minimal Hepatic Encephalopathy

2020 ◽  
Vol 17 (10) ◽  
pp. 3645
Author(s):  
Agnieszka Stawicka ◽  
Jerzy Jaroszewicz ◽  
Justyna Zbrzeźniak ◽  
Natalia Sołowianowicz ◽  
Aleksandra Woszczenko ◽  
...  
Keyword(s):  
Hepatic Encephalopathy ◽  
Inhibitory Control ◽  
Minimal Hepatic Encephalopathy ◽  
Meld Score ◽  
Decompensated Cirrhosis ◽  
Control Test ◽  
Moderate Sensitivity ◽  
Inhibitory Control Test ◽  
End Stage

Background: Minimal hepatic encephalopathy (MHE) refers to a number of neuropsychiatric and neurophysiological disorders in patients with cirrhosis who do not show abnormalities on physical examination or in clinical tests. The aim of this study was to determine the prevalence, risk factors, and predictive value of minimal hepatic encephalopathy and the usefulness of the inhibitory control test (ICT) in the diagnosis. Methods: Seventy patients (mean age 53 years, range 24−77) with liver cirrhosis were enrolled in the study. MHE was diagnosed based on PHES (psychometric hepatic encephalopathy score) and ICT. PHES and ICT were validated in a group of 56 control subjects. Results: Minimal hepatic encephalopathy was diagnosed using PHES in 21 patients (30%). ICT diagnosed MHE in 30 patients (42%), and the test had a sensitivity of 65% and a specificity of 57% compared to PHES. The ICT score (lures/target accuracy rate) correlated with the age of subjects (R = 0.35, p = 0.002) and only slightly with education (education in years R = −0.22, p = 0.06). MHE diagnosed with PHES or ICT was associated with a significantly higher model of end-stage liver disease (MELD) score in the follow-up. MHE diagnosed with ICT was correlated with a significantly higher incidence of symptoms of decompensated cirrhosis (p = 0.02) in the follow-up. Conclusions: ICT had moderate sensitivity and specificity in diagnosing MHE compared to PHES. Importantly, MHE detected with PHES or ICT was associated with poorer survival and a more severe progression of the disease.

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