Long term impact of vonoprazan‐based Helicobacter pylori treatment on gut microbiota and its relation to post‐treatment body weight changes

Helicobacter ◽  
2021 ◽  
Author(s):  
Sho Suzuki ◽  
Takuji Gotoda ◽  
Chika Takano ◽  
Toshiki Horii ◽  
Tomomi Sugita ◽  
...  
2017 ◽  
Vol 34 (03) ◽  
pp. 156-167
Author(s):  
A. Nyongesa ◽  
N. Patel ◽  
E. Wango ◽  
D. Onyango

Abstract Introduction: This study investigated short- and long-term effects of khat (Catha edulis) on hypophyseal, epididymal and testicular morphology, body weight and temperature changes and haematological parameters of rabbits. Materials and Methods: Twenty five male New Zealand White rabbits, divided into five groups were used. First four groups were administered, via intra-gastric tube, 1.5, 4.5, 13.5 and 40.5 g/kg body weight respectively of khat extract thrice a week for 8 weeks while controls received normal saline. Short-term and long-term effects were evaluated for hypophyseal, epididymal and testicular morphology, body temperature as well as body weight changes, food consumption and haematological parameters. Data on haematological parameters, body weight changes, body temperature and food consumption was done using one-way ANOVA at 95% confidence interval using SPSS version 12.0. Results: There was vacuolation in spermatogonia and spermatocytes at high doses while epididymides and hypophyses were unaffected. A significant decrease (P<0.05) in body weight of treatment groups correlated with reduced food intake with increasing doses and chronicity of exposure. Packed cell volume, red blood cell count and haemoglobin concentration decreased while white blood cell count increased with increasing doses. Conclusion: Khat extract had direct effects on spermatogenesis compounded by poor body weight gain, hyperthermia and blood volume loss.


2004 ◽  
Vol 80 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Vicky Drapeau ◽  
Jean-Pierre Després ◽  
Claude Bouchard ◽  
Lucie Allard ◽  
Guy Fournier ◽  
...  

Nutrients ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 1953 ◽  
Author(s):  
Tessa Van Elten ◽  
Mireille. Van Poppel ◽  
Reinoud Gemke ◽  
Henk Groen ◽  
Annemieke Hoek ◽  
...  

The degree to which individuals change their lifestyle in response to interventions differs and this variation could affect cardiometabolic health. We examined if changes in dietary intake, physical activity and weight of obese infertile women during the first six months of the LIFEstyle trial were associated with cardiometabolic health 3–8 years later (N = 50–78). Lifestyle was assessed using questionnaires and weight was measured at baseline, 3 and 6 months after randomization. BMI, blood pressure, body composition, pulse wave velocity, glycemic parameters and lipid profile were assessed 3–8 years after randomization. Decreases in savory and sweet snack intake were associated with lower HOMA-IR 3–8 years later, but these associations disappeared after adjustment for current lifestyle. No other associations between changes in lifestyle or body weight during the first six months after randomization with cardiovascular health 3–8 years later were observed. In conclusion, reductions in snack intake were associated with reduced insulin resistance 3–8 years later, but adjustment for current lifestyle reduced these associations. This indicates that changing lifestyle is an important first step, but maintaining this change is needed for improving cardiometabolic health in the long-term.


2019 ◽  
Vol 44 (2) ◽  
pp. 377-387 ◽  
Author(s):  
Kelvin H. M. Kwok ◽  
Mikael Rydén ◽  
Daniel P. Andersson ◽  
Gallic Beauchef ◽  
Christelle Guere ◽  
...  

1980 ◽  
Vol 95 (1) ◽  
pp. 39-45
Author(s):  
I. D. McArthur

SummaryA survey of sheep production was undertaken in rangeland areas of western Afghanistan to provide basic information of ewe body-weight changes throughout the year and on production variables, including mortality and lambing performance. Ewes lost up to 31% of body weight between December and March and mortality over the same period was 7%. On the basis of the results of this survey, an experiment was made to test the effect on lambing performance of pre-lambing supplementation of range-based ewes.Supplementation reduced weight losses in ewes, but the feeding treatments did not produce significant results in terms of lamb birth weights or survival to 10 days. However, there were indications that selective feeding of weak ewes can produce economic benefits, given that the costs of supervising such animals are minimal and the price of grain supplements is low relative to the price of meat.


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