scholarly journals Cardiometabolic Health in Relation to Lifestyle and Body Weight Changes 3–8 Years Earlier

Nutrients ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 1953 ◽  
Author(s):  
Tessa Van Elten ◽  
Mireille. Van Poppel ◽  
Reinoud Gemke ◽  
Henk Groen ◽  
Annemieke Hoek ◽  
...  
Keyword(s):  
Physical Activity ◽  
Insulin Resistance ◽  
Body Weight ◽  
Cardiovascular Health ◽  
Pulse Wave ◽  
Cardiometabolic Health ◽  
Weight Changes ◽  
Body Weight Changes ◽  
Infertile Women

The degree to which individuals change their lifestyle in response to interventions differs and this variation could affect cardiometabolic health. We examined if changes in dietary intake, physical activity and weight of obese infertile women during the first six months of the LIFEstyle trial were associated with cardiometabolic health 3–8 years later (N = 50–78). Lifestyle was assessed using questionnaires and weight was measured at baseline, 3 and 6 months after randomization. BMI, blood pressure, body composition, pulse wave velocity, glycemic parameters and lipid profile were assessed 3–8 years after randomization. Decreases in savory and sweet snack intake were associated with lower HOMA-IR 3–8 years later, but these associations disappeared after adjustment for current lifestyle. No other associations between changes in lifestyle or body weight during the first six months after randomization with cardiovascular health 3–8 years later were observed. In conclusion, reductions in snack intake were associated with reduced insulin resistance 3–8 years later, but adjustment for current lifestyle reduced these associations. This indicates that changing lifestyle is an important first step, but maintaining this change is needed for improving cardiometabolic health in the long-term.

scholarly journals High khat dose and long-term exposure impairs spermatogenesis: experimental study using rabbit model

2017 ◽  
Vol 34 (03) ◽  
pp. 156-167
Author(s):  
A. Nyongesa ◽  
N. Patel ◽  
E. Wango ◽  
D. Onyango
Keyword(s):  
Body Weight ◽  
Body Temperature ◽  
Blood Cell ◽  
Haematological Parameters ◽  
Long Term Effects ◽  
Weight Changes ◽  
Blood Cell Count ◽  
Body Weight Changes ◽  
Testicular Morphology

Abstract Introduction: This study investigated short- and long-term effects of khat (Catha edulis) on hypophyseal, epididymal and testicular morphology, body weight and temperature changes and haematological parameters of rabbits. Materials and Methods: Twenty five male New Zealand White rabbits, divided into five groups were used. First four groups were administered, via intra-gastric tube, 1.5, 4.5, 13.5 and 40.5 g/kg body weight respectively of khat extract thrice a week for 8 weeks while controls received normal saline. Short-term and long-term effects were evaluated for hypophyseal, epididymal and testicular morphology, body temperature as well as body weight changes, food consumption and haematological parameters. Data on haematological parameters, body weight changes, body temperature and food consumption was done using one-way ANOVA at 95% confidence interval using SPSS version 12.0. Results: There was vacuolation in spermatogonia and spermatocytes at high doses while epididymides and hypophyses were unaffected. A significant decrease (P<0.05) in body weight of treatment groups correlated with reduced food intake with increasing doses and chronicity of exposure. Packed cell volume, red blood cell count and haemoglobin concentration decreased while white blood cell count increased with increasing doses. Conclusion: Khat extract had direct effects on spermatogenesis compounded by poor body weight gain, hyperthermia and blood volume loss.

scholarly journals Modification in body weight associated with antiepileptic drugs

2010 ◽  
Vol 68 (2) ◽  
pp. 277-281 ◽  
Author(s):  
Camilla N. De Gaspari ◽  
Carlos A.M. Guerreiro
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Body Weight ◽  
Weight Gain ◽  
Antiepileptic Drugs ◽  
Body Mass ◽  
Dietary Habits ◽  
Weight Changes ◽  
Body Weight Changes ◽  
Epileptic Patients

Antiepileptic drugs (AED) may cause body weight changes. OBJECTIVE: To evaluate the dietary habits and body weight associated with AED in epileptic patients. METHOD: Sixty-six patients were subjected to two interviews, and had their weight and body mass index calculated and compared at both times, interval between six to eight months. RESULTS: It was observed that 59.1% showed weight gain. The patients who had no weight gain had a greater proportion of individuals who engaged in some form of physical activity. However, of the 45 patients who maintained their initial dietary and medication pattern, 75.6% recorded a weight gain. Weight gain was seen in 66.7% of patients on carbamazepine (n=18), 60% on valproate (n=5), 50% on carbamazepine+clobazam treatment (n=14), and 58.3% of patients on other(s) polytherapy (n=12). CONCLUSION: The patient should be alerted to possible weight gain, and should be advised about dieting and participating in regular physical activity.

scholarly journals Body Weight Changes in Hyperthyroidism: Timing and Possible Explanations during a One Year Repeated Measurement Study

2020 ◽  
pp. 1-7
Author(s):  
Jesper Karmisholt ◽  
Allan Carlé ◽  
Stig Andersen
Keyword(s):  
Physical Activity ◽  
Energy Efficiency ◽  
Body Weight ◽  
Thyroid Hormones ◽  
Physical Activity Level ◽  
Activity Level ◽  
First Year ◽  
Weight Changes ◽  
Body Weight Changes ◽  
Measurement Study

<b><i>Background:</i></b> Weight gain during treatment of hyperthyroidism is a frequent and for many patients unwanted outcome. With this repeated measurement study, we explored the timing of weight changes during the first year of antithyroid drug (ATD) treatment and assessed the correlation between body weight changes and changes in thyroid hormones, resting energy expenditure (REE), physical activity level, and energy efficiency. <b><i>Methods:</i></b> Patients with new onset hyperthyroidism were investigated every second month during the first year of ATD treatment. At each investigation, the following were measured: body weight, thyroid hormone concentrations, physical activity level, and daily number of steps, REE, and exercise performance. <b><i>Results:</i></b> Two men and eleven women, all sedentary, mean age 49(SD: 9.3) years were included. Significant changes after 1 year occurred for body weight (68.9–74.1 kg), thyroid hormones (free T3 [fT3] 17.5 to 4.42 pmol/L), REE (1,630–1,484 kcal/24 h), and energy efficiency at lower (50 W) workloads (16.0–17.6%). In individual patients, only REE and fT3 correlated to changes in body weight. Physical activity level did not change during treatment. <b><i>Conclusion:</i></b> In this study, treatment of hyperthyroidism was associated with marked increase in body weight in the patients. This increase correlated to a decrease in REE and only to a negligible extent to changes in energy efficiency and not at all to changes in physical activity level of daily living.

scholarly journals Modifications in food-group consumption are related to long-term body-weight changes

2004 ◽  
Vol 80 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Vicky Drapeau ◽  
Jean-Pierre Després ◽  
Claude Bouchard ◽  
Lucie Allard ◽  
Guy Fournier ◽  
...  
Keyword(s):  
Body Weight ◽  
Food Group ◽  
Weight Changes ◽  
Body Weight Changes
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